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Results: 1 to 20 of 42

1.

High-throughput phosphotyrosine profiling using SH2 domains.

Machida K, Thompson CM, Dierck K, Jablonowski K, Kärkkäinen S, Liu B, Zhang H, Nash PD, Newman DK, Nollau P, Pawson T, Renkema GH, Saksela K, Schiller MR, Shin DG, Mayer BJ.

Mol Cell. 2007 Jun 22;26(6):899-915.

PMID:
17588523
[PubMed - indexed for MEDLINE]
Free Article
2.

The ARP2/3 complex: an actin nucleator comes of age.

Goley ED, Welch MD.

Nat Rev Mol Cell Biol. 2006 Oct;7(10):713-26. Review.

PMID:
16990851
[PubMed - indexed for MEDLINE]
3.

Circumventing resistance to kinase-inhibitor therapy.

Druker BJ.

N Engl J Med. 2006 Jun 15;354(24):2594-6. No abstract available.

PMID:
16775240
[PubMed - indexed for MEDLINE]
4.

Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase.

Nagar B, Hantschel O, Seeliger M, Davies JM, Weis WI, Superti-Furga G, Kuriyan J.

Mol Cell. 2006 Mar 17;21(6):787-98.

PMID:
16543148
[PubMed - indexed for MEDLINE]
Free Article
5.

A common phosphotyrosine signature for the Bcr-Abl kinase.

Goss VL, Lee KA, Moritz A, Nardone J, Spek EJ, MacNeill J, Rush J, Comb MJ, Polakiewicz RD.

Blood. 2006 Jun 15;107(12):4888-97. Epub 2006 Feb 23.

PMID:
16497976
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Allosteric inhibitors of Bcr-abl-dependent cell proliferation.

Adrián FJ, Ding Q, Sim T, Velentza A, Sloan C, Liu Y, Zhang G, Hur W, Ding S, Manley P, Mestan J, Fabbro D, Gray NS.

Nat Chem Biol. 2006 Feb;2(2):95-102. Epub 2006 Jan 15.

PMID:
16415863
[PubMed - indexed for MEDLINE]
7.

The crystal structure of a c-Src complex in an active conformation suggests possible steps in c-Src activation.

Cowan-Jacob SW, Fendrich G, Manley PW, Jahnke W, Fabbro D, Liebetanz J, Meyer T.

Structure. 2005 Jun;13(6):861-71.

PMID:
15939018
[PubMed - indexed for MEDLINE]
Free Article
8.

Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation.

Leng Y, Zhang J, Badour K, Arpaia E, Freeman S, Cheung P, Siu M, Siminovitch K.

Proc Natl Acad Sci U S A. 2005 Jan 25;102(4):1098-103. Epub 2005 Jan 18.

PMID:
15657136
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Regulation of the c-Abl and Bcr-Abl tyrosine kinases.

Hantschel O, Superti-Furga G.

Nat Rev Mol Cell Biol. 2004 Jan;5(1):33-44. Review.

PMID:
14708008
[PubMed - indexed for MEDLINE]
10.

Controlling Abl: auto-inhibition and co-inhibition?

Wang JY.

Nat Cell Biol. 2004 Jan;6(1):3-7. Review.

PMID:
14704671
[PubMed - indexed for MEDLINE]
11.

Chronic myeloid leukemia--advances in biology and new approaches to treatment.

Goldman JM, Melo JV.

N Engl J Med. 2003 Oct 9;349(15):1451-64. Review. No abstract available.

PMID:
14534339
[PubMed - indexed for MEDLINE]
12.

Regulation of F-actin-dependent processes by the Abl family of tyrosine kinases.

Woodring PJ, Hunter T, Wang JY.

J Cell Sci. 2003 Jul 1;116(Pt 13):2613-26. Review.

PMID:
12775773
[PubMed - indexed for MEDLINE]
Free Article
13.

Two distinct phosphorylation pathways have additive effects on Abl family kinase activation.

Tanis KQ, Veach D, Duewel HS, Bornmann WG, Koleske AJ.

Mol Cell Biol. 2003 Jun;23(11):3884-96.

PMID:
12748290
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Cancer: Escape from inhibition.

Courtneidge SA.

Nature. 2003 Apr 24;422(6934):827-8. No abstract available.

PMID:
12712187
[PubMed - indexed for MEDLINE]
15.

Structural basis for the autoinhibition of c-Abl tyrosine kinase.

Nagar B, Hantschel O, Young MA, Scheffzek K, Veach D, Bornmann W, Clarkson B, Superti-Furga G, Kuriyan J.

Cell. 2003 Mar 21;112(6):859-71.

PMID:
12654251
[PubMed - indexed for MEDLINE]
16.

A myristoyl/phosphotyrosine switch regulates c-Abl.

Hantschel O, Nagar B, Guettler S, Kretzschmar J, Dorey K, Kuriyan J, Superti-Furga G.

Cell. 2003 Mar 21;112(6):845-57.

PMID:
12654250
[PubMed - indexed for MEDLINE]
17.

Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL.

Azam M, Latek RR, Daley GQ.

Cell. 2003 Mar 21;112(6):831-43.

PMID:
12654249
[PubMed - indexed for MEDLINE]
18.

c-Src binds alpha II spectrin's Src homology 3 (SH3) domain and blocks calpain susceptibility by phosphorylating Tyr1176.

Nedrelow JH, Cianci CD, Morrow JS.

J Biol Chem. 2003 Feb 28;278(9):7735-41. Epub 2002 Nov 20.

PMID:
12446661
[PubMed - indexed for MEDLINE]
Free Article
19.

BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to STI571: a prospective study.

von Bubnoff N, Schneller F, Peschel C, Duyster J.

Lancet. 2002 Feb 9;359(9305):487-91.

PMID:
11853795
[PubMed - indexed for MEDLINE]
20.

Autoinhibition of c-Abl.

Pluk H, Dorey K, Superti-Furga G.

Cell. 2002 Jan 25;108(2):247-59.

PMID:
11832214
[PubMed - indexed for MEDLINE]

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