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Results: 1 to 20 of 25

1.

Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1.

Bruey JM, Bruey-Sedano N, Luciano F, Zhai D, Balpai R, Xu C, Kress CL, Bailly-Maitre B, Li X, Osterman A, Matsuzawa S, Terskikh AV, Faustin B, Reed JC.

Cell. 2007 Apr 6;129(1):45-56.

PMID:
17418785
[PubMed - indexed for MEDLINE]
Free Article
2.

Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma.

Luciano F, Krajewska M, Ortiz-Rubio P, Krajewski S, Zhai D, Faustin B, Bruey JM, Bailly-Maitre B, Lichtenstein A, Kolluri SK, Satterthwait AC, Zhang XK, Reed JC.

Blood. 2007 May 1;109(9):3849-55. Epub 2007 Jan 16. Erratum in: Blood. 2009 Feb 12;113(7):1613.

PMID:
17227826
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities.

Reed JC.

Cell Death Differ. 2006 Aug;13(8):1378-86. Epub 2006 Jun 2. Review.

PMID:
16729025
[PubMed - indexed for MEDLINE]
Free Article
4.

Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members.

Certo M, Del Gaizo Moore V, Nishino M, Wei G, Korsmeyer S, Armstrong SA, Letai A.

Cancer Cell. 2006 May;9(5):351-65.

PMID:
16697956
[PubMed - indexed for MEDLINE]
Free Article
5.

Comparison of chemical inhibitors of antiapoptotic Bcl-2-family proteins.

Zhai D, Jin C, Satterthwait AC, Reed JC.

Cell Death Differ. 2006 Aug;13(8):1419-21. Epub 2006 Apr 28. No abstract available.

PMID:
16645636
[PubMed - indexed for MEDLINE]
Free Article
6.

BH3-only proteins in cell death initiation, malignant disease and anticancer therapy.

Labi V, Erlacher M, Kiessling S, Villunger A.

Cell Death Differ. 2006 Aug;13(8):1325-38. Epub 2006 Apr 28. Review.

PMID:
16645634
[PubMed - indexed for MEDLINE]
Free Article
7.

Life in the balance: how BH3-only proteins induce apoptosis.

Willis SN, Adams JM.

Curr Opin Cell Biol. 2005 Dec;17(6):617-25. Epub 2005 Oct 21. Review.

PMID:
16243507
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.

Willis SN, Chen L, Dewson G, Wei A, Naik E, Fletcher JI, Adams JM, Huang DC.

Genes Dev. 2005 Jun 1;19(11):1294-305. Epub 2005 May 18.

PMID:
15901672
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.

Kuwana T, Bouchier-Hayes L, Chipuk JE, Bonzon C, Sullivan BA, Green DR, Newmeyer DD.

Mol Cell. 2005 Feb 18;17(4):525-35.

PMID:
15721256
[PubMed - indexed for MEDLINE]
Free Article
10.

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function.

Chen L, Willis SN, Wei A, Smith BJ, Fletcher JI, Hinds MG, Colman PM, Day CL, Adams JM, Huang DC.

Mol Cell. 2005 Feb 4;17(3):393-403.

PMID:
15694340
[PubMed - indexed for MEDLINE]
Free Article
11.

Humanin binds and nullifies Bid activity by blocking its activation of Bax and Bak.

Zhai D, Luciano F, Zhu X, Guo B, Satterthwait AC, Reed JC.

J Biol Chem. 2005 Apr 22;280(16):15815-24. Epub 2005 Jan 20.

PMID:
15661737
[PubMed - indexed for MEDLINE]
Free Article
12.

The domains of apoptosis: a genomics perspective.

Reed JC, Doctor KS, Godzik A.

Sci STKE. 2004 Jun 22;2004(239):re9. Review.

PMID:
15226512
[PubMed - indexed for MEDLINE]
13.

Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3.

Lin B, Kolluri SK, Lin F, Liu W, Han YH, Cao X, Dawson MI, Reed JC, Zhang XK.

Cell. 2004 Feb 20;116(4):527-40.

PMID:
14980220
[PubMed - indexed for MEDLINE]
Free Article
14.

Characterization of the anti-apoptotic mechanism of Bcl-B.

Zhai D, Ke N, Zhang H, Ladror U, Joseph M, Eichinger A, Godzik A, Ng SC, Reed JC.

Biochem J. 2003 Nov 15;376(Pt 1):229-36.

PMID:
12921534
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics.

Letai A, Bassik MC, Walensky LD, Sorcinelli MD, Weiler S, Korsmeyer SJ.

Cancer Cell. 2002 Sep;2(3):183-92.

PMID:
12242151
[PubMed - indexed for MEDLINE]
Free Article
16.

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death.

Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB, Korsmeyer SJ.

Science. 2001 Apr 27;292(5517):727-30.

PMID:
11326099
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

BH3-Only proteins-essential initiators of apoptotic cell death.

Huang DC, Strasser A.

Cell. 2000 Dec 8;103(6):839-42. Review. No abstract available.

PMID:
11136969
[PubMed - indexed for MEDLINE]
Free Article
18.

Structure of Bax: coregulation of dimer formation and intracellular localization.

Suzuki M, Youle RJ, Tjandra N.

Cell. 2000 Nov 10;103(4):645-54.

PMID:
11106734
[PubMed - indexed for MEDLINE]
Free Article
19.

Mechanisms of apoptosis.

Reed JC.

Am J Pathol. 2000 Nov;157(5):1415-30.

PMID:
11073801
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Mitochondrial control of cell death.

Kroemer G, Reed JC.

Nat Med. 2000 May;6(5):513-9. Review.

PMID:
10802706
[PubMed - indexed for MEDLINE]

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