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Results: 1 to 20 of 40

1.

Thioredoxin-interacting protein (Txnip) is a critical regulator of hepatic glucose production.

Chutkow WA, Patwari P, Yoshioka J, Lee RT.

J Biol Chem. 2008 Jan 25;283(4):2397-406. Epub 2007 Nov 12.

PMID:
17998203
[PubMed - indexed for MEDLINE]
Free Article
2.

TXNIP regulates peripheral glucose metabolism in humans.

Parikh H, Carlsson E, Chutkow WA, Johansson LE, Storgaard H, Poulsen P, Saxena R, Ladd C, Schulze PC, Mazzini MJ, Jensen CB, Krook A, Björnholm M, Tornqvist H, Zierath JR, Ridderstråle M, Altshuler D, Lee RT, Vaag A, Groop LC, Mootha VK.

PLoS Med. 2007 May;4(5):e158.

PMID:
17472435
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Glucotoxicity in the INS-1 rat insulinoma cell line is mediated by the orphan nuclear receptor small heterodimer partner.

Park KG, Lee KM, Seo HY, Suh JH, Kim HS, Wang L, Won KC, Lee HW, Park JY, Lee KU, Kim JG, Kim BW, Choi HS, Lee IK.

Diabetes. 2007 Feb;56(2):431-7.

PMID:
17259388
[PubMed - indexed for MEDLINE]
Free Article
4.

Exenatide inhibits beta-cell apoptosis by decreasing thioredoxin-interacting protein.

Chen J, Couto FM, Minn AH, Shalev A.

Biochem Biophys Res Commun. 2006 Aug 4;346(3):1067-74. Epub 2006 Jun 13.

PMID:
16782054
[PubMed - indexed for MEDLINE]
5.

The interaction of thioredoxin with Txnip. Evidence for formation of a mixed disulfide by disulfide exchange.

Patwari P, Higgins LJ, Chutkow WA, Yoshioka J, Lee RT.

J Biol Chem. 2006 Aug 4;281(31):21884-91. Epub 2006 Jun 9.

PMID:
16766796
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities.

Cnop M, Welsh N, Jonas JC, Jörns A, Lenzen S, Eizirik DL.

Diabetes. 2005 Dec;54 Suppl 2:S97-107. Review.

PMID:
16306347
[PubMed - indexed for MEDLINE]
Free Article
7.

Gene expression profiling in INS-1 cells overexpressing thioredoxin-interacting protein.

Minn AH, Pise-Masison CA, Radonovich M, Brady JN, Wang P, Kendziorski C, Shalev A.

Biochem Biophys Res Commun. 2005 Oct 28;336(3):770-8.

PMID:
16143294
[PubMed - indexed for MEDLINE]
8.

ERK1/2-dependent activation of transcription factors required for acute and chronic effects of glucose on the insulin gene promoter.

Lawrence MC, McGlynn K, Park BH, Cobb MH.

J Biol Chem. 2005 Jul 22;280(29):26751-9. Epub 2005 May 16.

PMID:
15899886
[PubMed - indexed for MEDLINE]
Free Article
9.

Functional and molecular defects of pancreatic islets in human type 2 diabetes.

Del Guerra S, Lupi R, Marselli L, Masini M, Bugliani M, Sbrana S, Torri S, Pollera M, Boggi U, Mosca F, Del Prato S, Marchetti P.

Diabetes. 2005 Mar;54(3):727-35.

PMID:
15734849
[PubMed - indexed for MEDLINE]
Free Article
10.

Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces beta-cell apoptosis.

Minn AH, Hafele C, Shalev A.

Endocrinology. 2005 May;146(5):2397-405. Epub 2005 Feb 10.

PMID:
15705778
[PubMed - indexed for MEDLINE]
11.

Type 2 diabetes-a matter of beta-cell life and death?

Rhodes CJ.

Science. 2005 Jan 21;307(5708):380-4.

PMID:
15662003
[PubMed - indexed for MEDLINE]
12.

Increased insulin translation from an insulin splice-variant overexpressed in diabetes, obesity, and insulin resistance.

Minn AH, Lan H, Rabaglia ME, Harlan DM, Peculis BA, Attie AD, Shalev A.

Mol Endocrinol. 2005 Mar;19(3):794-803. Epub 2004 Nov 18.

PMID:
15550470
[PubMed - indexed for MEDLINE]
13.

Thioredoxin-interacting protein deficiency disrupts the fasting-feeding metabolic transition.

Sheth SS, Castellani LW, Chari S, Wagg C, Thipphavong CK, Bodnar JS, Tontonoz P, Attie AD, Lopaschuk GD, Lusis AJ.

J Lipid Res. 2005 Jan;46(1):123-34. Epub 2004 Nov 1.

PMID:
15520447
[PubMed - indexed for MEDLINE]
Free Article
14.

MAP kinases and their roles in pancreatic beta-cells.

Khoo S, Gibson TB, Arnette D, Lawrence M, January B, McGlynn K, Vanderbilt CA, Griffen SC, German MS, Cobb MH.

Cell Biochem Biophys. 2004;40(3 Suppl):191-200. Review.

PMID:
15289654
[PubMed - indexed for MEDLINE]
15.

D-Glyceraldehyde causes production of intracellular peroxide in pancreatic islets, oxidative stress, and defective beta cell function via non-mitochondrial pathways.

Takahashi H, Tran PO, LeRoy E, Harmon JS, Tanaka Y, Robertson RP.

J Biol Chem. 2004 Sep 3;279(36):37316-23. Epub 2004 Jun 22.

PMID:
15213233
[PubMed - indexed for MEDLINE]
Free Article
16.

Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein.

Schulze PC, Yoshioka J, Takahashi T, He Z, King GL, Lee RT.

J Biol Chem. 2004 Jul 16;279(29):30369-74. Epub 2004 May 5.

PMID:
15128745
[PubMed - indexed for MEDLINE]
Free Article
17.

Role of oxidative stress in pancreatic beta-cell dysfunction.

Kajimoto Y, Kaneto H.

Ann N Y Acad Sci. 2004 Apr;1011:168-76.

PMID:
15126294
[PubMed - indexed for MEDLINE]
18.

Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals.

Hui TY, Sheth SS, Diffley JM, Potter DW, Lusis AJ, Attie AD, Davis RA.

J Biol Chem. 2004 Jun 4;279(23):24387-93. Epub 2004 Mar 26.

PMID:
15047687
[PubMed - indexed for MEDLINE]
Free Article
19.

Gene and protein kinase expression profiling of reactive oxygen species-associated lipotoxicity in the pancreatic beta-cell line MIN6.

Wang X, Li H, De Leo D, Guo W, Koshkin V, Fantus IG, Giacca A, Chan CB, Der S, Wheeler MB.

Diabetes. 2004 Jan;53(1):129-40.

PMID:
14693707
[PubMed - indexed for MEDLINE]
Free Article
20.

Oxidative stress is a mediator of glucose toxicity in insulin-secreting pancreatic islet cell lines.

Wu L, Nicholson W, Knobel SM, Steffner RJ, May JM, Piston DW, Powers AC.

J Biol Chem. 2004 Mar 26;279(13):12126-34. Epub 2003 Dec 19.

PMID:
14688272
[PubMed - indexed for MEDLINE]
Free Article

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