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Results: 1 to 20 of 37

1.

Dietary phytochemicals regulate whole-body CYP1A1 expression through an arylhydrocarbon receptor nuclear translocator-dependent system in gut.

Ito S, Chen C, Satoh J, Yim S, Gonzalez FJ.

J Clin Invest. 2007 Jul;117(7):1940-50.

PMID:
17607366
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Generation of 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-) mouse line.

Dragin N, Uno S, Wang B, Dalton TP, Nebert DW.

Biochem Biophys Res Commun. 2007 Aug 3;359(3):635-42. Epub 2007 Jun 6.

PMID:
17560947
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis.

Nebert DW, Dalton TP.

Nat Rev Cancer. 2006 Dec;6(12):947-60. Review.

PMID:
17128211
[PubMed - indexed for MEDLINE]
4.

Selective induction of intestinal CYP3A23 by 1alpha,25-dihydroxyvitamin D3 in rats.

Xu Y, Iwanaga K, Zhou C, Cheesman MJ, Farin F, Thummel KE.

Biochem Pharmacol. 2006 Jul 28;72(3):385-92.

PMID:
16769037
[PubMed - indexed for MEDLINE]
5.

Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate.

Uno S, Dalton TP, Dragin N, Curran CP, Derkenne S, Miller ML, Shertzer HG, Gonzalez FJ, Nebert DW.

Mol Pharmacol. 2006 Apr;69(4):1103-14. Epub 2005 Dec 23.

PMID:
16377763
[PubMed - indexed for MEDLINE]
Free Article
6.

Cytochrome P450 expression and activities in human tongue cells and their modulation by green tea extract.

Yang SP, Raner GM.

Toxicol Appl Pharmacol. 2005 Jan 15;202(2):140-50.

PMID:
15629189
[PubMed - indexed for MEDLINE]
7.

The induction of cytochrome P450 3A5 (CYP3A5) in the human liver and intestine is mediated by the xenobiotic sensors pregnane X receptor (PXR) and constitutively activated receptor (CAR).

Burk O, Koch I, Raucy J, Hustert E, Eichelbaum M, Brockmöller J, Zanger UM, Wojnowski L.

J Biol Chem. 2004 Sep 10;279(37):38379-85. Epub 2004 Jul 12.

PMID:
15252010
[PubMed - indexed for MEDLINE]
Free Article
8.

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.

Nelson DR, Zeldin DC, Hoffman SM, Maltais LJ, Wain HM, Nebert DW.

Pharmacogenetics. 2004 Jan;14(1):1-18. Review.

PMID:
15128046
[PubMed - indexed for MEDLINE]
9.

Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation.

Uno S, Dalton TP, Derkenne S, Curran CP, Miller ML, Shertzer HG, Nebert DW.

Mol Pharmacol. 2004 May;65(5):1225-37.

PMID:
15102951
[PubMed - indexed for MEDLINE]
Free Article
10.

Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer.

Nebert DW, Dalton TP, Okey AB, Gonzalez FJ.

J Biol Chem. 2004 Jun 4;279(23):23847-50. Epub 2004 Mar 17. Review.

PMID:
15028720
[PubMed - indexed for MEDLINE]
Free Article
11.

Characterization of mouse small intestinal cytochrome P450 expression.

Zhang QY, Dunbar D, Kaminsky LS.

Drug Metab Dispos. 2003 Nov;31(11):1346-51.

PMID:
14570766
[PubMed - indexed for MEDLINE]
Free Article
12.

Benzpyrene hydroxylase activity in the gastrointestinal tract.

WATTENBERG LW, LEONG JL, STRAND PJ.

Cancer Res. 1962 Oct;22:1120-5. No abstract available.

PMID:
13999236
[PubMed - indexed for MEDLINE]
Free Article
13.

TNF-alpha -induced endothelial cell adhesion molecule expression is cytochrome P-450 monooxygenase dependent.

Sasaki M, Ostanin D, Elrod JW, Oshima T, Jordan P, Itoh M, Joh T, Minagar A, Alexander JS.

Am J Physiol Cell Physiol. 2003 Feb;284(2):C422-8. Epub 2002 Sep 4.

PMID:
12388057
[PubMed - indexed for MEDLINE]
Free Article
14.

Clinical importance of the cytochromes P450.

Nebert DW, Russell DW.

Lancet. 2002 Oct 12;360(9340):1155-62. Review.

PMID:
12387968
[PubMed - indexed for MEDLINE]
15.

Downregulation of intestinal cytochrome p450 in chronic renal failure.

Leblond FA, Petrucci M, Dubé P, Bernier G, Bonnardeaux A, Pichette V.

J Am Soc Nephrol. 2002 Jun;13(6):1579-85.

PMID:
12039987
[PubMed - indexed for MEDLINE]
Free Article
16.

"Gene-swap knock-in" cassette in mice to study allelic differences in human genes.

Nebert DW, Dalton TP, Stuart GW, Carvan MJ 3rd.

Ann N Y Acad Sci. 2000;919:148-70.

PMID:
11083106
[PubMed - indexed for MEDLINE]
17.

Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery.

Dalton TP, Dieter MZ, Matlib RS, Childs NL, Shertzer HG, Genter MB, Nebert DW.

Biochem Biophys Res Commun. 2000 Jan 7;267(1):184-9.

PMID:
10623596
[PubMed - indexed for MEDLINE]
18.

Effects of a chargrilled meat diet on expression of CYP3A, CYP1A, and P-glycoprotein levels in healthy volunteers.

Fontana RJ, Lown KS, Paine MF, Fortlage L, Santella RM, Felton JS, Knize MG, Greenberg A, Watkins PB.

Gastroenterology. 1999 Jul;117(1):89-98.

PMID:
10381914
[PubMed - indexed for MEDLINE]
19.

Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro.

Winer J, Jung CK, Shackel I, Williams PM.

Anal Biochem. 1999 May 15;270(1):41-9.

PMID:
10328763
[PubMed - indexed for MEDLINE]
20.

Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas.

Buters JT, Sakai S, Richter T, Pineau T, Alexander DL, Savas U, Doehmer J, Ward JM, Jefcoate CR, Gonzalez FJ.

Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):1977-82.

PMID:
10051580
[PubMed - indexed for MEDLINE]
Free PMC Article
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