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Results: 1 to 20 of 92

1.

Therapies for Alzheimer's disease.

Melnikova I.

Nat Rev Drug Discov. 2007 May;6(5):341-2. No abstract available.

PMID:
17539055
[PubMed - indexed for MEDLINE]
2.

Imaging beta-amyloid burden in aging and dementia.

Rowe CC, Ng S, Ackermann U, Gong SJ, Pike K, Savage G, Cowie TF, Dickinson KL, Maruff P, Darby D, Smith C, Woodward M, Merory J, Tochon-Danguy H, O'Keefe G, Klunk WE, Mathis CA, Price JC, Masters CL, Villemagne VL.

Neurology. 2007 May 15;68(20):1718-25.

PMID:
17502554
[PubMed - indexed for MEDLINE]
3.

Cortical biochemistry in MCI and Alzheimer disease: lack of correlation with clinical diagnosis.

Forman MS, Mufson EJ, Leurgans S, Pratico D, Joyce S, Leight S, Lee VM, Trojanowski JQ.

Neurology. 2007 Mar 6;68(10):757-63.

PMID:
17339583
[PubMed - indexed for MEDLINE]
4.

PET of brain amyloid and tau in mild cognitive impairment.

Small GW, Kepe V, Ercoli LM, Siddarth P, Bookheimer SY, Miller KJ, Lavretsky H, Burggren AC, Cole GM, Vinters HV, Thompson PM, Huang SC, Satyamurthy N, Phelps ME, Barrio JR.

N Engl J Med. 2006 Dec 21;355(25):2652-63.

PMID:
17182990
[PubMed - indexed for MEDLINE]
Free Article
5.

Two-year follow-up of amyloid deposition in patients with Alzheimer's disease.

Klunk WE, Mathis CA, Price JC, Lopresti BJ, DeKosky ST.

Brain. 2006 Nov;129(Pt 11):2805-7. No abstract available.

PMID:
17071918
[PubMed - indexed for MEDLINE]
Free Article
6.

Therapeutic approaches to Alzheimer's disease.

Klafki HW, Staufenbiel M, Kornhuber J, Wiltfang J.

Brain. 2006 Nov;129(Pt 11):2840-55. Epub 2006 Oct 3. Review.

PMID:
17018549
[PubMed - indexed for MEDLINE]
Free Article
7.

[11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease.

Mintun MA, Larossa GN, Sheline YI, Dence CS, Lee SY, Mach RH, Klunk WE, Mathis CA, DeKosky ST, Morris JC.

Neurology. 2006 Aug 8;67(3):446-52.

PMID:
16894106
[PubMed - indexed for MEDLINE]
8.

The gamma-secretase complex: membrane-embedded proteolytic ensemble.

Wolfe MS.

Biochemistry. 2006 Jul 4;45(26):7931-9. Review.

PMID:
16800619
[PubMed - indexed for MEDLINE]
9.

Mild cognitive impairment.

Gauthier S, Reisberg B, Zaudig M, Petersen RC, Ritchie K, Broich K, Belleville S, Brodaty H, Bennett D, Chertkow H, Cummings JL, de Leon M, Feldman H, Ganguli M, Hampel H, Scheltens P, Tierney MC, Whitehouse P, Winblad B; International Psychogeriatric Association Expert Conference on mild cognitive impairment.

Lancet. 2006 Apr 15;367(9518):1262-70. Review.

PMID:
16631882
[PubMed - indexed for MEDLINE]
10.

Has the amyloid cascade hypothesis for Alzheimer's disease been proved?

Hardy J.

Curr Alzheimer Res. 2006 Feb;3(1):71-3. Review.

PMID:
16472206
[PubMed - indexed for MEDLINE]
11.

Novel Abeta peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease.

Zhou J, Fonseca MI, Kayed R, Hernandez I, Webster SD, Yazan O, Cribbs DH, Glabe CG, Tenner AJ.

J Neuroinflammation. 2005 Dec 7;2:28.

PMID:
16332263
[PubMed]
Free PMC Article
12.

Simplified quantification of Pittsburgh Compound B amyloid imaging PET studies: a comparative analysis.

Lopresti BJ, Klunk WE, Mathis CA, Hoge JA, Ziolko SK, Lu X, Meltzer CC, Schimmel K, Tsopelas ND, DeKosky ST, Price JC.

J Nucl Med. 2005 Dec;46(12):1959-72.

PMID:
16330558
[PubMed - indexed for MEDLINE]
Free Article
13.

gamma-Secretase substrate selectivity can be modulated directly via interaction with a nucleotide-binding site.

Fraering PC, Ye W, LaVoie MJ, Ostaszewski BL, Selkoe DJ, Wolfe MS.

J Biol Chem. 2005 Dec 23;280(51):41987-96. Epub 2005 Oct 19.

PMID:
16236717
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Amyloid: toward terminology clarification. Report from the Nomenclature Committee of the International Society of Amyloidosis.

Westermark P, Benson MD, Buxbaum JN, Cohen AS, Frangione B, Ikeda S, Masters CL, Merlini G, Saraiva MJ, Sipe JD; Nomenclature Committee of the International Society of Amyloidosis.

Amyloid. 2005 Mar;12(1):1-4. Review.

PMID:
16076605
[PubMed - indexed for MEDLINE]
15.

Safety, tolerability, and changes in amyloid beta concentrations after administration of a gamma-secretase inhibitor in volunteers.

Siemers E, Skinner M, Dean RA, Gonzales C, Satterwhite J, Farlow M, Ness D, May PC.

Clin Neuropharmacol. 2005 May-Jun;28(3):126-32.

PMID:
15965311
[PubMed - indexed for MEDLINE]
16.

Effects of Abeta immunization (AN1792) on MRI measures of cerebral volume in Alzheimer disease.

Fox NC, Black RS, Gilman S, Rossor MN, Griffith SG, Jenkins L, Koller M; AN1792(QS-21)-201 Study.

Neurology. 2005 May 10;64(9):1563-72.

PMID:
15883317
[PubMed - indexed for MEDLINE]
17.

Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial.

Gilman S, Koller M, Black RS, Jenkins L, Griffith SG, Fox NC, Eisner L, Kirby L, Rovira MB, Forette F, Orgogozo JM; AN1792(QS-21)-201 Study Team.

Neurology. 2005 May 10;64(9):1553-62.

PMID:
15883316
[PubMed - indexed for MEDLINE]
18.

Meningoencephalitis associated with passive immunization of a transgenic murine model of Alzheimer's amyloidosis.

Lee EB, Leng LZ, Lee VM, Trojanowski JQ.

FEBS Lett. 2005 May 9;579(12):2564-8. Epub 2005 Apr 7.

PMID:
15862291
[PubMed - indexed for MEDLINE]
Free Article
19.

Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo.

Klyubin I, Walsh DM, Lemere CA, Cullen WK, Shankar GM, Betts V, Spooner ET, Jiang L, Anwyl R, Selkoe DJ, Rowan MJ.

Nat Med. 2005 May;11(5):556-61. Epub 2005 Apr 17.

PMID:
15834427
[PubMed - indexed for MEDLINE]
20.

Emerging prospects for the disease-modifying treatment of Alzheimer's disease.

Walker LC, Ibegbu CC, Todd CW, Robinson HL, Jucker M, LeVine H 3rd, Gandy S.

Biochem Pharmacol. 2005 Apr 1;69(7):1001-8. Review.

PMID:
15763538
[PubMed - indexed for MEDLINE]

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