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References for PMC Articles for PubMed (Select 17607365)


STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo.

Pietrangelo A, Dierssen U, Valli L, Garuti C, Rump A, Corradini E, Ernst M, Klein C, Trautwein C.

Gastroenterology. 2007 Jan;132(1):294-300. Epub 2006 Oct 17. Erratum in: Gastroenterology. 2007 Mar;132(3):1208.


STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation.

Verga Falzacappa MV, Vujic Spasic M, Kessler R, Stolte J, Hentze MW, Muckenthaler MU.

Blood. 2007 Jan 1;109(1):353-8. Epub 2006 Aug 31.


Hereditary hemochromatosis.

Pietrangelo A.

Biochim Biophys Acta. 2006 Jul;1763(7):700-10. Epub 2006 May 27. Review.


Interleukin-6 induces hepcidin expression through STAT3.

Wrighting DM, Andrews NC.

Blood. 2006 Nov 1;108(9):3204-9. Epub 2006 Jul 11.


Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6.

Truksa J, Peng H, Lee P, Beutler E.

Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10289-93. Epub 2006 Jun 26.


Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression.

Babitt JL, Huang FW, Wrighting DM, Xia Y, Sidis Y, Samad TA, Campagna JA, Chung RT, Schneyer AL, Woolf CJ, Andrews NC, Lin HY.

Nat Genet. 2006 May;38(5):531-9. Epub 2006 Apr 9.


A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression.

Wang RH, Li C, Xu X, Zheng Y, Xiao C, Zerfas P, Cooperman S, Eckhaus M, Rouault T, Mishra L, Deng CX.

Cell Metab. 2005 Dec;2(6):399-409.


Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells.

Zhang AS, West AP Jr, Wyman AE, Bjorkman PJ, Enns CA.

J Biol Chem. 2005 Oct 7;280(40):33885-94. Epub 2005 Aug 15.


Comparative studies of duodenal and macrophage ferroportin proteins.

Canonne-Hergaux F, Donovan A, Delaby C, Wang HJ, Gros P.

Am J Physiol Gastrointest Liver Physiol. 2006 Jan;290(1):G156-63. Epub 2005 Aug 4.


A mouse model of juvenile hemochromatosis.

Huang FW, Pinkus JL, Pinkus GS, Fleming MD, Andrews NC.

J Clin Invest. 2005 Aug;115(8):2187-91.


Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload.

Niederkofler V, Salie R, Arber S.

J Clin Invest. 2005 Aug;115(8):2180-6.


Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin.

Lin L, Goldberg YP, Ganz T.

Blood. 2005 Oct 15;106(8):2884-9. Epub 2005 Jul 5.


Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor.

Babitt JL, Zhang Y, Samad TA, Xia Y, Tang J, Campagna JA, Schneyer AL, Woolf CJ, Lin HY.

J Biol Chem. 2005 Aug 19;280(33):29820-7. Epub 2005 Jun 23.


Anemia of chronic disease.

Weiss G, Goodnough LT.

N Engl J Med. 2005 Mar 10;352(10):1011-23. Review. No abstract available.


Regulation of hepcidin transcription by interleukin-1 and interleukin-6.

Lee P, Peng H, Gelbart T, Wang L, Beutler E.

Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):1906-10. Epub 2005 Jan 31.


DRAGON, a bone morphogenetic protein co-receptor.

Samad TA, Rebbapragada A, Bell E, Zhang Y, Sidis Y, Jeong SJ, Campagna JA, Perusini S, Fabrizio DA, Schneyer AL, Lin HY, Brivanlou AH, Attisano L, Woolf CJ.

J Biol Chem. 2005 Apr 8;280(14):14122-9. Epub 2005 Jan 25.


Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization.

Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, Kaplan J.

Science. 2004 Dec 17;306(5704):2090-3. Epub 2004 Oct 28.


Hepcidin is decreased in TFR2 hemochromatosis.

Nemeth E, Roetto A, Garozzo G, Ganz T, Camaschella C.

Blood. 2005 Feb 15;105(4):1803-6. Epub 2004 Oct 14.


Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis.

Kawabata H, Fleming RE, Gui D, Moon SY, Saitoh T, O'Kelly J, Umehara Y, Wano Y, Said JW, Koeffler HP.

Blood. 2005 Jan 1;105(1):376-81. Epub 2004 Sep 2.


IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin.

Nemeth E, Rivera S, Gabayan V, Keller C, Taudorf S, Pedersen BK, Ganz T.

J Clin Invest. 2004 May;113(9):1271-6.

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