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Items: 1 to 20 of 79

1.

Leukemogenic AML1-ETO fusion protein upregulates expression of connexin 43: the role in AML 1-ETO-induced growth arrest in leukemic cells.

Li X, Xu YB, Wang Q, Lu Y, Zheng Y, Wang YC, Lübbert M, Zhao KW, Chen GQ.

J Cell Physiol. 2006 Sep;208(3):594-601.

PMID:
16741927
2.

The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity.

Liu Y, Cheney MD, Gaudet JJ, Chruszcz M, Lukasik SM, Sugiyama D, Lary J, Cole J, Dauter Z, Minor W, Speck NA, Bushweller JH.

Cancer Cell. 2006 Apr;9(4):249-60.

3.

AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1.

Nishida S, Hosen N, Shirakata T, Kanato K, Yanagihara M, Nakatsuka S, Hoshida Y, Nakazawa T, Harada Y, Tatsumi N, Tsuboi A, Kawakami M, Oka Y, Oji Y, Aozasa K, Kawase I, Sugiyama H.

Blood. 2006 Apr 15;107(8):3303-12. Epub 2005 Dec 27.

4.

A novel and cytogenetically cryptic t(7;21)(p22;q22) in acute myeloid leukemia results in fusion of RUNX1 with the ubiquitin-specific protease gene USP42.

Paulsson K, Békássy AN, Olofsson T, Mitelman F, Johansson B, Panagopoulos I.

Leukemia. 2006 Feb;20(2):224-9.

PMID:
16357831
5.

Epigenetic inactivation of the CIP/KIP cell-cycle control pathway in acute leukemias.

Chim CS, Wong AS, Kwong YL.

Am J Hematol. 2005 Dec;80(4):282-7.

6.

The hematopoietic transcription factor AML1 (RUNX1) is negatively regulated by the cell cycle protein cyclin D3.

Peterson LF, Boyapati A, Ranganathan V, Iwama A, Tenen DG, Tsai S, Zhang DE.

Mol Cell Biol. 2005 Dec;25(23):10205-19.

7.

Normal and transforming functions of RUNX1: a perspective.

Mikhail FM, Sinha KK, Saunthararajah Y, Nucifora G.

J Cell Physiol. 2006 Jun;207(3):582-93. Review.

PMID:
16250015
8.

p21WAF1/CIP1 regulates the p300 sumoylation motif CRD1 through a C-terminal domain independently of cyclin/CDK binding.

Garcia-Wilson E, Perkins ND.

Cell Cycle. 2005 Aug;4(8):1113-9. Epub 2005 Aug 1.

PMID:
16082198
9.

The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice.

Schessl C, Rawat VP, Cusan M, Deshpande A, Kohl TM, Rosten PM, Spiekermann K, Humphries RK, Schnittger S, Kern W, Hiddemann W, Quintanilla-Martinez L, Bohlander SK, Feuring-Buske M, Buske C.

J Clin Invest. 2005 Aug;115(8):2159-68. Epub 2005 Jul 14.

10.

Absence of p21(CIP 1), p27(KIP 1) and p 57(KIP 2) methylation in MDS and AML.

Brakensiek K, Länger F, Kreipe H, Lehmann U.

Leuk Res. 2005 Nov;29(11):1357-60.

PMID:
15936816
11.

Silencing p21(Waf1/Cip1/Sdi1) expression increases gene transduction efficiency in primitive human hematopoietic cells.

Zhang J, Attar E, Cohen K, Crumpacker C, Scadden D.

Gene Ther. 2005 Oct;12(19):1444-52.

PMID:
15877047
12.

p21WAF1/CIP1 selectively controls the transcriptional activity of estrogen receptor alpha.

Fritah A, Saucier C, Mester J, Redeuilh G, Sabbah M.

Mol Cell Biol. 2005 Mar;25(6):2419-30.

13.

AML1-FOG2 fusion protein in myelodysplasia.

Chan EM, Comer EM, Brown FC, Richkind KE, Holmes ML, Chong BH, Shiffman R, Zhang DE, Slovak ML, Willman CL, Noguchi CT, Li Y, Heiber DJ, Kwan L, Chan RJ, Vance GH, Ramsey HC, Hromas RA.

Blood. 2005 Jun 1;105(11):4523-6. Epub 2005 Feb 10.

14.

Deletion of an AML1-ETO C-terminal NcoR/SMRT-interacting region strongly induces leukemia development.

Yan M, Burel SA, Peterson LF, Kanbe E, Iwasaki H, Boyapati A, Hines R, Akashi K, Zhang DE.

Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):17186-91. Epub 2004 Nov 29.

15.

Stem cell expression of the AML1/ETO fusion protein induces a myeloproliferative disorder in mice.

Fenske TS, Pengue G, Mathews V, Hanson PT, Hamm SE, Riaz N, Graubert TA.

Proc Natl Acad Sci U S A. 2004 Oct 19;101(42):15184-9. Epub 2004 Oct 11.

16.

AML1-ETO decreases ETO-2 (MTG16) interactions with nuclear receptor corepressor, an effect that impairs granulocyte differentiation.

Ibañez V, Sharma A, Buonamici S, Verma A, Kalakonda S, Wang J, Kadkol S, Saunthararajah Y.

Cancer Res. 2004 Jul 1;64(13):4547-54.

17.

The 8;21 translocation in leukemogenesis.

Peterson LF, Zhang DE.

Oncogene. 2004 May 24;23(24):4255-62. Review.

PMID:
15156181
18.

Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.

Müller-Tidow C, Steffen B, Cauvet T, Tickenbrock L, Ji P, Diederichs S, Sargin B, Köhler G, Stelljes M, Puccetti E, Ruthardt M, deVos S, Hiebert SW, Koeffler HP, Berdel WE, Serve H.

Mol Cell Biol. 2004 Apr;24(7):2890-904.

19.

Flt3 mutation activates p21WAF1/CIP1 gene expression through the action of STAT5.

Takahashi S, Harigae H, Kaku M, Sasaki T, Licht JD.

Biochem Biophys Res Commun. 2004 Mar 26;316(1):85-92.

PMID:
15003515
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