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Results: 1 to 20 of 43

1.

NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN.

Wang X, Trotman LC, Koppie T, Alimonti A, Chen Z, Gao Z, Wang J, Erdjument-Bromage H, Tempst P, Cordon-Cardo C, Pandolfi PP, Jiang X.

Cell. 2007 Jan 12;128(1):129-39.

PMID:
17218260
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Ubiquitin and ubiquitin-like proteins in cancer pathogenesis.

Hoeller D, Hecker CM, Dikic I.

Nat Rev Cancer. 2006 Oct;6(10):776-88. Review.

PMID:
16990855
[PubMed - indexed for MEDLINE]
3.

Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling.

Massoumi R, Chmielarska K, Hennecke K, Pfeifer A, Fässler R.

Cell. 2006 May 19;125(4):665-77.

PMID:
16713561
[PubMed - indexed for MEDLINE]
Free Article
4.

Identification of a tumour suppressor network opposing nuclear Akt function.

Trotman LC, Alimonti A, Scaglioni PP, Koutcher JA, Cordon-Cardo C, Pandolfi PP.

Nature. 2006 May 25;441(7092):523-7. Epub 2006 May 7.

PMID:
16680151
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Class reunion: PTEN joins the nuclear crew.

Lian Z, Di Cristofano A.

Oncogene. 2005 Nov 14;24(50):7394-400. Review.

PMID:
16288286
[PubMed - indexed for MEDLINE]
6.

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis.

Chen Z, Trotman LC, Shaffer D, Lin HK, Dotan ZA, Niki M, Koutcher JA, Scher HI, Ludwig T, Gerald W, Cordon-Cardo C, Pandolfi PP.

Nature. 2005 Aug 4;436(7051):725-30.

PMID:
16079851
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor suppression.

Ma L, Teruya-Feldstein J, Behrendt N, Chen Z, Noda T, Hino O, Cordon-Cardo C, Pandolfi PP.

Genes Dev. 2005 Aug 1;19(15):1779-86. Epub 2005 Jul 18.

PMID:
16027168
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Proteolysis: from the lysosome to ubiquitin and the proteasome.

Ciechanover A.

Nat Rev Mol Cell Biol. 2005 Jan;6(1):79-87.

PMID:
15688069
[PubMed - indexed for MEDLINE]
9.

Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import.

Plafker SM, Plafker KS, Weissman AM, Macara IG.

J Cell Biol. 2004 Nov 22;167(4):649-59. Epub 2004 Nov 15.

PMID:
15545318
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Highly penetrant hereditary cancer syndromes.

Nagy R, Sweet K, Eng C.

Oncogene. 2004 Aug 23;23(38):6445-70. Review.

PMID:
15322516
[PubMed - indexed for MEDLINE]
11.

The biology and clinical relevance of the PTEN tumor suppressor pathway.

Sansal I, Sellers WR.

J Clin Oncol. 2004 Jul 15;22(14):2954-63. Review.

PMID:
15254063
[PubMed - indexed for MEDLINE]
12.

PTEN function: how normal cells control it and tumour cells lose it.

Leslie NR, Downes CP.

Biochem J. 2004 Aug 15;382(Pt 1):1-11. Review.

PMID:
15193142
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Principles of tumor suppression.

Sherr CJ.

Cell. 2004 Jan 23;116(2):235-46. Review.

PMID:
14744434
[PubMed - indexed for MEDLINE]
14.

The tumour-suppressor function of PTEN requires an N-terminal lipid-binding motif.

Walker SM, Leslie NR, Perera NM, Batty IH, Downes CP.

Biochem J. 2004 Apr 15;379(Pt 2):301-7.

PMID:
14711368
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Pten dose dictates cancer progression in the prostate.

Trotman LC, Niki M, Dotan ZA, Koutcher JA, Di Cristofano A, Xiao A, Khoo AS, Roy-Burman P, Greenberg NM, Van Dyke T, Cordon-Cardo C, Pandolfi PP.

PLoS Biol. 2003 Dec;1(3):E59. Epub 2003 Oct 27.

PMID:
14691534
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Mono- versus polyubiquitination: differential control of p53 fate by Mdm2.

Li M, Brooks CL, Wu-Baer F, Chen D, Baer R, Gu W.

Science. 2003 Dec 12;302(5652):1972-5.

PMID:
14671306
[PubMed - indexed for MEDLINE]
Free Article
17.

PTEN: one gene, many syndromes.

Eng C.

Hum Mutat. 2003 Sep;22(3):183-98. Review.

PMID:
12938083
[PubMed - indexed for MEDLINE]
18.

PTEN and p53: who will get the upper hand?

Trotman LC, Pandolfi PP.

Cancer Cell. 2003 Feb;3(2):97-9. No abstract available.

PMID:
12620402
[PubMed - indexed for MEDLINE]
19.

The p53-Mdm2 module and the ubiquitin system.

Michael D, Oren M.

Semin Cancer Biol. 2003 Feb;13(1):49-58. Review.

PMID:
12507556
[PubMed - indexed for MEDLINE]
20.

PTEN mutational spectra, expression levels, and subcellular localization in microsatellite stable and unstable colorectal cancers.

Zhou XP, Loukola A, Salovaara R, Nystrom-Lahti M, Peltomäki P, de la Chapelle A, Aaltonen LA, Eng C.

Am J Pathol. 2002 Aug;161(2):439-47.

PMID:
12163369
[PubMed - indexed for MEDLINE]
Free PMC Article

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