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Results: 1 to 20 of 56

1.

Caffeine metabolites are inhibitors of the nuclear enzyme poly(ADP-ribose)polymerase-1 at physiological concentrations.

Geraets L, Moonen HJ, Wouters EF, Bast A, Hageman GJ.

Biochem Pharmacol. 2006 Sep 28;72(7):902-10. Epub 2006 Jul 25.

PMID:
16870158
[PubMed - indexed for MEDLINE]
2.

Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.

Alano CC, Kauppinen TM, Valls AV, Swanson RA.

Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9685-90. Epub 2006 Jun 12.

PMID:
16769901
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The parp-1 inhibitor ino-1001 facilitates hemodynamic stabilization without affecting DNA repair in porcine thoracic aortic cross-clamping-induced ischemia/reperfusion.

Hauser B, Gröger M, Ehrmann U, Albicini M, Brückner UB, Schelzig H, Venkatesh B, Li H, Szabó C, Speit G, Radermacher P, Kick J.

Shock. 2006 Jun;25(6):633-40.

PMID:
16721272
[PubMed - indexed for MEDLINE]
4.

Poly(ADP-ribose) polymerase-1-deficient mice are protected from angiotensin II-induced cardiac hypertrophy.

Pillai JB, Gupta M, Rajamohan SB, Lang R, Raman J, Gupta MP.

Am J Physiol Heart Circ Physiol. 2006 Oct;291(4):H1545-53. Epub 2006 Apr 21.

PMID:
16632544
[PubMed - indexed for MEDLINE]
Free Article
5.

KIF4 motor regulates activity-dependent neuronal survival by suppressing PARP-1 enzymatic activity.

Midorikawa R, Takei Y, Hirokawa N.

Cell. 2006 Apr 21;125(2):371-83.

PMID:
16630823
[PubMed - indexed for MEDLINE]
Free Article
6.

Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damage.

Kolthur-Seetharam U, Dantzer F, McBurney MW, de Murcia G, Sassone-Corsi P.

Cell Cycle. 2006 Apr;5(8):873-7. Epub 2006 Apr 17.

PMID:
16628003
[PubMed - indexed for MEDLINE]
Free Article
7.

Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2.

Kauppinen TM, Chan WY, Suh SW, Wiggins AK, Huang EJ, Swanson RA.

Proc Natl Acad Sci U S A. 2006 May 2;103(18):7136-41. Epub 2006 Apr 20.

PMID:
16627622
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Minocycline for short-term neuroprotection.

Elewa HF, Hilali H, Hess DC, Machado LS, Fagan SC.

Pharmacotherapy. 2006 Apr;26(4):515-21. Review.

PMID:
16553511
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation.

Xu Y, Huang S, Liu ZG, Han J.

J Biol Chem. 2006 Mar 31;281(13):8788-95. Epub 2006 Jan 30.

PMID:
16446354
[PubMed - indexed for MEDLINE]
Free Article
10.

Role of poly(ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: endothelial dysfunction, as a common underlying theme.

Pacher P, Szabó C.

Antioxid Redox Signal. 2005 Nov-Dec;7(11-12):1568-80. Review.

PMID:
16356120
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Theophylline prevents NAD+ depletion via PARP-1 inhibition in human pulmonary epithelial cells.

Moonen HJ, Geraets L, Vaarhorst A, Bast A, Wouters EF, Hageman GJ.

Biochem Biophys Res Commun. 2005 Dec 30;338(4):1805-10. Epub 2005 Nov 2.

PMID:
16289039
[PubMed - indexed for MEDLINE]
12.

Vitamin D receptor modulators for inflammation and cancer.

Yee YK, Chintalacharuvu SR, Lu J, Nagpal S.

Mini Rev Med Chem. 2005 Aug;5(8):761-78. Review.

PMID:
16101412
[PubMed - indexed for MEDLINE]
13.

Gender differences in the endotoxin-induced inflammatory and vascular responses: potential role of poly(ADP-ribose) polymerase activation.

Mabley JG, Horváth EM, Murthy KG, Zsengellér Z, Vaslin A, Benko R, Kollai M, Szabó C.

J Pharmacol Exp Ther. 2005 Nov;315(2):812-20. Epub 2005 Aug 3.

PMID:
16079296
[PubMed - indexed for MEDLINE]
Free Article
14.

Antioxidant properties of minocycline: neuroprotection in an oxidative stress assay and direct radical-scavenging activity.

Kraus RL, Pasieczny R, Lariosa-Willingham K, Turner MS, Jiang A, Trauger JW.

J Neurochem. 2005 Aug;94(3):819-27.

PMID:
16033424
[PubMed - indexed for MEDLINE]
15.

The influence of ATP on poly(ADP-ribose) metabolism.

Bauer PI, Kenesi E, Mendeleyev J, Kun E.

Int J Mol Med. 2005 Aug;16(2):321-4.

PMID:
16012769
[PubMed - indexed for MEDLINE]
16.

Clinical perspectives of PARP inhibitors.

Graziani G, Szabó C.

Pharmacol Res. 2005 Jul;52(1):109-18. Review.

PMID:
15911339
[PubMed - indexed for MEDLINE]
17.

PARP-1 inhibition to treat cancer, ischemia, inflammation.

Graziani G, Battaini F, Zhang J.

Pharmacol Res. 2005 Jul;52(1):1-4. No abstract available.

PMID:
15911328
[PubMed - indexed for MEDLINE]
18.

Minocycline confers early but transient protection in the immature brain following focal cerebral ischemia-reperfusion.

Fox C, Dingman A, Derugin N, Wendland MF, Manabat C, Ji S, Ferriero DM, Vexler ZS.

J Cereb Blood Flow Metab. 2005 Sep;25(9):1138-49. Erratum in: J Cereb Blood Flow Metab. 2006 Mar;26(3):446.

PMID:
15874975
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors.

Jagtap P, Szabó C.

Nat Rev Drug Discov. 2005 May;4(5):421-40. Review.

PMID:
15864271
[PubMed - indexed for MEDLINE]
20.

Minocycline inhibits oxidative stress and decreases in vitro and in vivo ischemic neuronal damage.

Morimoto N, Shimazawa M, Yamashima T, Nagai H, Hara H.

Brain Res. 2005 May 17;1044(1):8-15. Epub 2005 Apr 13.

PMID:
15862784
[PubMed - indexed for MEDLINE]

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