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Results: 1 to 20 of 53

1.

Critical nodes in signalling pathways: insights into insulin action.

Taniguchi CM, Emanuelli B, Kahn CR.

Nat Rev Mol Cell Biol. 2006 Feb;7(2):85-96. Review.

PMID:
16493415
[PubMed - indexed for MEDLINE]
2.

AMPK activation increases fatty acid oxidation in skeletal muscle by activating PPARalpha and PGC-1.

Lee WJ, Kim M, Park HS, Kim HS, Jeon MJ, Oh KS, Koh EH, Won JC, Kim MS, Oh GT, Yoon M, Lee KU, Park JY.

Biochem Biophys Res Commun. 2006 Feb 3;340(1):291-5. Epub 2005 Dec 12.

PMID:
16364253
[PubMed - indexed for MEDLINE]
3.

Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKalpha2 but not AMPKalpha1.

Sakamoto K, Zarrinpashneh E, Budas GR, Pouleur AC, Dutta A, Prescott AR, Vanoverschelde JL, Ashworth A, Jovanović A, Alessi DR, Bertrand L.

Am J Physiol Endocrinol Metab. 2006 May;290(5):E780-8. Epub 2005 Dec 6.

PMID:
16332922
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin.

Shaw RJ, Lamia KA, Vasquez D, Koo SH, Bardeesy N, Depinho RA, Montminy M, Cantley LC.

Science. 2005 Dec 9;310(5754):1642-6. Epub 2005 Nov 24.

PMID:
16308421
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

AMP-activated protein kinase alpha2 activity is not essential for contraction- and hyperosmolarity-induced glucose transport in skeletal muscle.

Fujii N, Hirshman MF, Kane EM, Ho RC, Peter LE, Seifert MM, Goodyear LJ.

J Biol Chem. 2005 Nov 25;280(47):39033-41. Epub 2005 Sep 26.

PMID:
16186119
[PubMed - indexed for MEDLINE]
Free Article
6.

Endurance training increases skeletal muscle LKB1 and PGC-1alpha protein abundance: effects of time and intensity.

Taylor EB, Lamb JD, Hurst RW, Chesser DG, Ellingson WJ, Greenwood LJ, Porter BB, Herway ST, Winder WW.

Am J Physiol Endocrinol Metab. 2005 Dec;289(6):E960-8. Epub 2005 Jul 12.

PMID:
16014350
[PubMed - indexed for MEDLINE]
Free Article
7.

Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction.

Sakamoto K, McCarthy A, Smith D, Green KA, Grahame Hardie D, Ashworth A, Alessi DR.

EMBO J. 2005 May 18;24(10):1810-20. Epub 2005 May 5.

PMID:
15889149
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Effects of alpha-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle.

Jørgensen SB, Wojtaszewski JF, Viollet B, Andreelli F, Birk JB, Hellsten Y, Schjerling P, Vaulont S, Neufer PD, Richter EA, Pilegaard H.

FASEB J. 2005 Jul;19(9):1146-8. Epub 2005 May 5.

PMID:
15878932
[PubMed - indexed for MEDLINE]
Free Article
9.

Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate.

Jaleel M, McBride A, Lizcano JM, Deak M, Toth R, Morrice NA, Alessi DR.

FEBS Lett. 2005 Feb 28;579(6):1417-23.

PMID:
15733851
[PubMed - indexed for MEDLINE]
Free Article
10.

Metabolic activation of AMP kinase in vascular smooth muscle.

Rubin LJ, Magliola L, Feng X, Jones AW, Hale CC.

J Appl Physiol (1985). 2005 Jan;98(1):296-306. Epub 2004 Sep 17.

PMID:
15377643
[PubMed - indexed for MEDLINE]
Free Article
11.

PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.

Koo SH, Satoh H, Herzig S, Lee CH, Hedrick S, Kulkarni R, Evans RM, Olefsky J, Montminy M.

Nat Med. 2004 May;10(5):530-4. Epub 2004 Apr 25. Erratum in: Nat Med. 2004 Jul;7(10):755.

PMID:
15107844
[PubMed - indexed for MEDLINE]
12.

Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR.

Sakamoto K, Göransson O, Hardie DG, Alessi DR.

Am J Physiol Endocrinol Metab. 2004 Aug;287(2):E310-7. Epub 2004 Apr 6.

PMID:
15068958
[PubMed - indexed for MEDLINE]
Free Article
13.

Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD.

Baas AF, Kuipers J, van der Wel NN, Batlle E, Koerten HK, Peters PJ, Clevers HC.

Cell. 2004 Feb 6;116(3):457-66.

PMID:
15016379
[PubMed - indexed for MEDLINE]
Free Article
14.

Overexpression or ablation of JNK in skeletal muscle has no effect on glycogen synthase activity.

Fujii N, Boppart MD, Dufresne SD, Crowley PF, Jozsi AC, Sakamoto K, Yu H, Aschenbach WG, Kim S, Miyazaki H, Rui L, White MF, Hirshman MF, Goodyear LJ.

Am J Physiol Cell Physiol. 2004 Jul;287(1):C200-8. Epub 2004 Mar 10.

PMID:
15013949
[PubMed - indexed for MEDLINE]
Free Article
15.

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.

Shaw RJ, Kosmatka M, Bardeesy N, Hurley RL, Witters LA, DePinho RA, Cantley LC.

Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3329-35. Epub 2004 Feb 25.

PMID:
14985505
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.

Lizcano JM, Göransson O, Toth R, Deak M, Morrice NA, Boudeau J, Hawley SA, Udd L, Mäkelä TP, Hardie DG, Alessi DR.

EMBO J. 2004 Feb 25;23(4):833-43. Epub 2004 Feb 19.

PMID:
14976552
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

LKB1 is the upstream kinase in the AMP-activated protein kinase cascade.

Woods A, Johnstone SR, Dickerson K, Leiper FC, Fryer LG, Neumann D, Schlattner U, Wallimann T, Carlson M, Carling D.

Curr Biol. 2003 Nov 11;13(22):2004-8.

PMID:
14614828
[PubMed - indexed for MEDLINE]
Free Article
18.

Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle.

Jørgensen SB, Viollet B, Andreelli F, Frøsig C, Birk JB, Schjerling P, Vaulont S, Richter EA, Wojtaszewski JF.

J Biol Chem. 2004 Jan 9;279(2):1070-9. Epub 2003 Oct 21.

PMID:
14573616
[PubMed - indexed for MEDLINE]
Free Article
19.

Cloning and characterization of mouse 5'-AMP-activated protein kinase gamma3 subunit.

Yu H, Fujii N, Hirshman MF, Pomerleau JM, Goodyear LJ.

Am J Physiol Cell Physiol. 2004 Feb;286(2):C283-92. Epub 2003 Sep 24.

PMID:
14512293
[PubMed - indexed for MEDLINE]
Free Article
20.

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade.

Hawley SA, Boudeau J, Reid JL, Mustard KJ, Udd L, Mäkelä TP, Alessi DR, Hardie DG.

J Biol. 2003;2(4):28. Epub 2003 Sep 24.

PMID:
14511394
[PubMed - indexed for MEDLINE]
Free PMC Article

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