Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 62

1.

Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model.

Tong KI, Katoh Y, Kusunoki H, Itoh K, Tanaka T, Yamamoto M.

Mol Cell Biol. 2006 Apr;26(8):2887-900.

PMID:
16581765
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer.

Padmanabhan B, Tong KI, Ohta T, Nakamura Y, Scharlock M, Ohtsuji M, Kang MI, Kobayashi A, Yokoyama S, Yamamoto M.

Mol Cell. 2006 Mar 3;21(5):689-700.

PMID:
16507366
[PubMed - indexed for MEDLINE]
Free Article
3.

CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1.

Lo SC, Hannink M.

Mol Cell Biol. 2006 Feb;26(4):1235-44.

PMID:
16449638
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Identification of sensor cysteines in human Keap1 modified by the cancer chemopreventive agent sulforaphane.

Hong F, Freeman ML, Liebler DC.

Chem Res Toxicol. 2005 Dec;18(12):1917-26.

PMID:
16359182
[PubMed - indexed for MEDLINE]
5.

Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1.

Kobayashi A, Kang MI, Watai Y, Tong KI, Shibata T, Uchida K, Yamamoto M.

Mol Cell Biol. 2006 Jan;26(1):221-9.

PMID:
16354693
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Gigaxonin interacts with tubulin folding cofactor B and controls its degradation through the ubiquitin-proteasome pathway.

Wang W, Ding J, Allen E, Zhu P, Zhang L, Vogel H, Yang Y.

Curr Biol. 2005 Nov 22;15(22):2050-5.

PMID:
16303566
[PubMed - indexed for MEDLINE]
Free Article
7.

Sequence and structural analysis of BTB domain proteins.

Stogios PJ, Downs GS, Jauhal JJ, Nandra SK, Privé GG.

Genome Biol. 2005;6(10):R82. Epub 2005 Sep 15.

PMID:
16207353
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Nrf2 as a target for cancer chemoprevention.

Yu X, Kensler T.

Mutat Res. 2005 Dec 11;591(1-2):93-102. Epub 2005 Jul 28. Review.

PMID:
16054659
[PubMed - indexed for MEDLINE]
9.

Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2.

Eggler AL, Liu G, Pezzuto JM, van Breemen RB, Mesecar AD.

Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10070-5. Epub 2005 Jul 8.

PMID:
16006525
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Specific patterns of electrophile adduction trigger Keap1 ubiquitination and Nrf2 activation.

Hong F, Sekhar KR, Freeman ML, Liebler DC.

J Biol Chem. 2005 Sep 9;280(36):31768-75. Epub 2005 Jun 28.

PMID:
15985429
[PubMed - indexed for MEDLINE]
Free Article
11.

Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway.

Zhang DD, Lo SC, Sun Z, Habib GM, Lieberman MW, Hannink M.

J Biol Chem. 2005 Aug 26;280(34):30091-9. Epub 2005 Jun 27.

PMID:
15983046
[PubMed - indexed for MEDLINE]
Free Article
12.

Nrf2 Possesses a redox-insensitive nuclear export signal overlapping with the leucine zipper motif.

Li W, Jain MR, Chen C, Yue X, Hebbar V, Zhou R, Kong AN.

J Biol Chem. 2005 Aug 5;280(31):28430-8. Epub 2005 May 23.

PMID:
15917227
[PubMed - indexed for MEDLINE]
Free Article
13.

Antioxidant and cytoprotective responses to redox stress.

Mathers J, Fraser JA, McMahon M, Saunders RD, Hayes JD, McLellan LI.

Biochem Soc Symp. 2004;(71):157-76. Review.

PMID:
15777020
[PubMed - indexed for MEDLINE]
14.

BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase.

Furukawa M, Xiong Y.

Mol Cell Biol. 2005 Jan;25(1):162-71.

PMID:
15601839
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome.

Katoh Y, Iida K, Kang MI, Kobayashi A, Mizukami M, Tong KI, McMahon M, Hayes JD, Itoh K, Yamamoto M.

Arch Biochem Biophys. 2005 Jan 15;433(2):342-50. Review.

PMID:
15581590
[PubMed - indexed for MEDLINE]
16.

Coot: model-building tools for molecular graphics.

Emsley P, Cowtan K.

Acta Crystallogr D Biol Crystallogr. 2004 Dec;60(Pt 12 Pt 1):2126-32. Epub 2004 Nov 26.

PMID:
15572765
[PubMed - indexed for MEDLINE]
17.

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.

Zhang DD, Lo SC, Cross JV, Templeton DJ, Hannink M.

Mol Cell Biol. 2004 Dec;24(24):10941-53.

PMID:
15572695
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Crystal structure of the Kelch domain of human Keap1.

Li X, Zhang D, Hannink M, Beamer LJ.

J Biol Chem. 2004 Dec 24;279(52):54750-8. Epub 2004 Oct 8.

PMID:
15475350
[PubMed - indexed for MEDLINE]
Free Article
19.

The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase.

Cullinan SB, Gordan JD, Jin J, Harper JW, Diehl JA.

Mol Cell Biol. 2004 Oct;24(19):8477-86.

PMID:
15367669
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Refinement of macromolecular structures by the maximum-likelihood method.

Murshudov GN, Vagin AA, Dodson EJ.

Acta Crystallogr D Biol Crystallogr. 1997 May 1;53(Pt 3):240-55.

PMID:
15299926
[PubMed]

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk