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Results: 1 to 20 of 36

1.

Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha.

Ferguson SS, Chen Y, LeCluyse EL, Negishi M, Goldstein JA.

Mol Pharmacol. 2005 Sep;68(3):747-57. Epub 2005 Jun 2.

PMID:
15933212
[PubMed - indexed for MEDLINE]
Free Article
2.

The nuclear receptors constitutive androstane receptor and pregnane X receptor cross-talk with hepatic nuclear factor 4alpha to synergistically activate the human CYP2C9 promoter.

Chen Y, Kissling G, Negishi M, Goldstein JA.

J Pharmacol Exp Ther. 2005 Sep;314(3):1125-33. Epub 2005 May 26.

PMID:
15919766
[PubMed - indexed for MEDLINE]
Free Article
3.

Hepatic expression of the UGT1A9 gene is governed by hepatocyte nuclear factor 4alpha.

Barbier O, Girard H, Inoue Y, Duez H, Villeneuve L, Kamiya A, Fruchart JC, Guillemette C, Gonzalez FJ, Staels B.

Mol Pharmacol. 2005 Jan;67(1):241-9. Epub 2004 Oct 6.

PMID:
15470081
[PubMed - indexed for MEDLINE]
Free Article
4.

Cytoplasmic localization of pregnane X receptor and ligand-dependent nuclear translocation in mouse liver.

Squires EJ, Sueyoshi T, Negishi M.

J Biol Chem. 2004 Nov 19;279(47):49307-14. Epub 2004 Sep 2.

PMID:
15347657
[PubMed - indexed for MEDLINE]
Free Article
5.

CAR, driving into the future.

Swales K, Negishi M.

Mol Endocrinol. 2004 Jul;18(7):1589-98. Epub 2004 Feb 26. Review.

PMID:
14988430
[PubMed - indexed for MEDLINE]
6.

Identification of the nuclear receptor CAR:HSP90 complex in mouse liver and recruitment of protein phosphatase 2A in response to phenobarbital.

Yoshinari K, Kobayashi K, Moore R, Kawamoto T, Negishi M.

FEBS Lett. 2003 Jul 31;548(1-3):17-20.

PMID:
12885400
[PubMed - indexed for MEDLINE]
Free Article
7.

Role of the hepatocyte nuclear factor 4alpha in control of the pregnane X receptor during fetal liver development.

Kamiya A, Inoue Y, Gonzalez FJ.

Hepatology. 2003 Jun;37(6):1375-84.

PMID:
12774017
[PubMed - indexed for MEDLINE]
8.

The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.

Tirona RG, Lee W, Leake BF, Lan LB, Cline CB, Lamba V, Parviz F, Duncan SA, Inoue Y, Gonzalez FJ, Schuetz EG, Kim RB.

Nat Med. 2003 Feb;9(2):220-4. Epub 2003 Jan 6.

PMID:
12514743
[PubMed - indexed for MEDLINE]
9.

Serine/threonine phosphorylation regulates HNF-4alpha-dependent redox-mediated iNOS expression in hepatocytes.

Guo H, Wei J, Inoue Y, Gonzalez FJ, Kuo PC.

Am J Physiol Cell Physiol. 2003 Apr;284(4):C1090-9. Epub 2002 Dec 4.

PMID:
12466152
[PubMed - indexed for MEDLINE]
Free Article
10.
11.

Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital.

Ueda A, Hamadeh HK, Webb HK, Yamamoto Y, Sueyoshi T, Afshari CA, Lehmann JM, Negishi M.

Mol Pharmacol. 2002 Jan;61(1):1-6.

PMID:
11752199
[PubMed - indexed for MEDLINE]
Free Article
12.

Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: a study using adenovirus-mediated antisense targeting.

Jover R, Bort R, Gómez-Lechón MJ, Castell JV.

Hepatology. 2001 Mar;33(3):668-75.

PMID:
11230748
[PubMed - indexed for MEDLINE]
13.

Regulation of phenobarbital-induction of CYP2B and CYP3A genes in rat cultured hepatocytes: involvement of several serine/threonine protein kinases and phosphatases.

Joannard F, Galisteo M, Corcos L, Guillouzo A, Lagadic-Gossmann D.

Cell Biol Toxicol. 2000;16(5):325-37.

PMID:
11201056
[PubMed - indexed for MEDLINE]
14.

Phenobarbital-elicited activation of nuclear receptor CAR in induction of cytochrome P450 genes.

Zelko I, Negishi M.

Biochem Biophys Res Commun. 2000 Oct 14;277(1):1-6. Review.

PMID:
11027630
[PubMed - indexed for MEDLINE]
15.

Acetylation regulates transcription factor activity at multiple levels.

Soutoglou E, Katrakili N, Talianidis I.

Mol Cell. 2000 Apr;5(4):745-51.

PMID:
10882110
[PubMed - indexed for MEDLINE]
Free Article
16.

Identification of phenobarbitone-modulated genes in mouse liver by differential display.

Garcia-Allan C, Lord PG, Loughlin JM, Orton TC, Sidaway JE.

J Biochem Mol Toxicol. 2000;14(2):65-72.

PMID:
10630419
[PubMed - indexed for MEDLINE]
17.

Involvement of cyclic nucleotide- and calcium-regulated pathways in phenobarbital-induced cytochrome P-450 3A expression in mouse primary hepatocytes.

Galisteo M, Marc N, Fautrel A, Guillouzo A, Corcos L, Lagadic-Gossmann D.

J Pharmacol Exp Ther. 1999 Sep;290(3):1270-7.

PMID:
10454503
[PubMed - indexed for MEDLINE]
Free Article
18.

Concise review of the cytochrome P450s and their roles in toxicology.

Omiecinski CJ, Remmel RP, Hosagrahara VP.

Toxicol Sci. 1999 Apr;48(2):151-6. Review. No abstract available.

PMID:
10353305
[PubMed - indexed for MEDLINE]
Free Article
19.

Dose-dependent biphasic effects of phenobarbital on growth and differentiation of primary culture rat hepatocytes.

Miyazaki M, Mars WM, Michalopoulos GK, Namba M.

J Gastroenterol Hepatol. 1998 Sep;13 Suppl:S78-82. Review.

PMID:
9792038
[PubMed - indexed for MEDLINE]
20.

The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene.

Honkakoski P, Zelko I, Sueyoshi T, Negishi M.

Mol Cell Biol. 1998 Oct;18(10):5652-8.

PMID:
9742082
[PubMed - indexed for MEDLINE]
Free PMC Article

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