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Results: 1 to 20 of 25

1.

Germline KRAS mutations cause Noonan syndrome.

Schubbert S, Zenker M, Rowe SL, Böll S, Klein C, Bollag G, van der Burgt I, Musante L, Kalscheuer V, Wehner LE, Nguyen H, West B, Zhang KY, Sistermans E, Rauch A, Niemeyer CM, Shannon K, Kratz CP.

Nat Genet. 2006 Mar;38(3):331-6. Epub 2006 Feb 12. Erratum in: Nat Genet. 2006 May;38(5):598.

PMID:
16474405
[PubMed - indexed for MEDLINE]
2.

Inherited predispositions and hyperactive Ras in myeloid leukemogenesis.

Lauchle JO, Braun BS, Loh ML, Shannon K.

Pediatr Blood Cancer. 2006 May 1;46(5):579-85. Review.

PMID:
16261595
[PubMed - indexed for MEDLINE]
3.

Focus on myeloproliferative diseases and myelodysplastic syndromes.

Van Etten RA, Shannon KM.

Cancer Cell. 2004 Dec;6(6):547-52. Review. No abstract available.

PMID:
15607959
[PubMed - indexed for MEDLINE]
4.

Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation.

Araki T, Mohi MG, Ismat FA, Bronson RT, Williams IR, Kutok JL, Yang W, Pao LI, Gilliland DG, Epstein JA, Neel BG.

Nat Med. 2004 Aug;10(8):849-57. Epub 2004 Jul 25.

PMID:
15273746
[PubMed - indexed for MEDLINE]
5.

Constitutive activation of the MEK/ERK pathway mediates all effects of oncogenic H-ras expression in primary erythroid progenitors.

Zhang J, Lodish HF.

Blood. 2004 Sep 15;104(6):1679-87. Epub 2004 May 27.

PMID:
15166036
[PubMed - indexed for MEDLINE]
Free Article
6.

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

Tuveson DA, Shaw AT, Willis NA, Silver DP, Jackson EL, Chang S, Mercer KL, Grochow R, Hock H, Crowley D, Hingorani SR, Zaks T, King C, Jacobetz MA, Wang L, Bronson RT, Orkin SH, DePinho RA, Jacks T.

Cancer Cell. 2004 Apr;5(4):375-87.

PMID:
15093544
[PubMed - indexed for MEDLINE]
7.

Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder.

Le DT, Kong N, Zhu Y, Lauchle JO, Aiyigari A, Braun BS, Wang E, Kogan SC, Le Beau MM, Parada L, Shannon KM.

Blood. 2004 Jun 1;103(11):4243-50. Epub 2004 Feb 24.

PMID:
14982883
[PubMed - indexed for MEDLINE]
Free Article
8.

Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease.

Chan IT, Kutok JL, Williams IR, Cohen S, Kelly L, Shigematsu H, Johnson L, Akashi K, Tuveson DA, Jacks T, Gilliland DG.

J Clin Invest. 2004 Feb;113(4):528-38.

PMID:
14966562
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder.

Braun BS, Tuveson DA, Kong N, Le DT, Kogan SC, Rozmus J, Le Beau MM, Jacks TE, Shannon KM.

Proc Natl Acad Sci U S A. 2004 Jan 13;101(2):597-602. Epub 2003 Dec 29.

PMID:
14699048
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis.

Loh ML, Vattikuti S, Schubbert S, Reynolds MG, Carlson E, Lieuw KH, Cheng JW, Lee CM, Stokoe D, Bonifas JM, Curtiss NP, Gotlib J, Meshinchi S, Le Beau MM, Emanuel PD, Shannon KM.

Blood. 2004 Mar 15;103(6):2325-31. Epub 2003 Nov 26.

PMID:
14644997
[PubMed - indexed for MEDLINE]
Free Article
11.

Role of Ras signaling in erythroid differentiation of mouse fetal liver cells: functional analysis by a flow cytometry-based novel culture system.

Zhang J, Socolovsky M, Gross AW, Lodish HF.

Blood. 2003 Dec 1;102(12):3938-46. Epub 2003 Aug 7.

PMID:
12907435
[PubMed - indexed for MEDLINE]
Free Article
12.
13.

Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia.

Tartaglia M, Niemeyer CM, Fragale A, Song X, Buechner J, Jung A, Hählen K, Hasle H, Licht JD, Gelb BD.

Nat Genet. 2003 Jun;34(2):148-50.

PMID:
12717436
[PubMed - indexed for MEDLINE]
14.

A validated decision model for treating the anaemia of myelodysplastic syndromes with erythropoietin + granulocyte colony-stimulating factor: significant effects on quality of life.

Hellström-Lindberg E, Gulbrandsen N, Lindberg G, Ahlgren T, Dahl IM, Dybedal I, Grimfors G, Hesse-Sundin E, Hjorth M, Kanter-Lewensohn L, Linder O, Luthman M, Löfvenberg E, Oberg G, Porwit-MacDonald A, Rådlund A, Samuelsson J, Tangen JM, Winquist I, Wisloff F; Scandinavian MDS Group.

Br J Haematol. 2003 Mar;120(6):1037-46.

PMID:
12648074
[PubMed - indexed for MEDLINE]
15.

The World Health Organization (WHO) classification of the myeloid neoplasms.

Vardiman JW, Harris NL, Brunning RD.

Blood. 2002 Oct 1;100(7):2292-302. Review.

PMID:
12239137
[PubMed - indexed for MEDLINE]
Free Article
16.

Role of the macrophage in erythropoiesis.

Sadahira Y, Mori M.

Pathol Int. 1999 Oct;49(10):841-8. Review.

PMID:
10571815
[PubMed - indexed for MEDLINE]
17.

Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction.

Socolovsky M, Fallon AE, Wang S, Brugnara C, Lodish HF.

Cell. 1999 Jul 23;98(2):181-91.

PMID:
10428030
[PubMed - indexed for MEDLINE]
Free Article
18.

Myelodysplastic syndrome, juvenile myelomonocytic leukemia, and acute myeloid leukemia associated with complete or partial monosomy 7. European Working Group on MDS in Childhood (EWOG-MDS).

Hasle H, Aricò M, Basso G, Biondi A, Cantù Rajnoldi A, Creutzig U, Fenu S, Fonatsch C, Haas OA, Harbott J, Kardos G, Kerndrup G, Mann G, Niemeyer CM, Ptoszkova H, Ritter J, Slater R, Starý J, Stollmann-Gibbels B, Testi AM, van Wering ER, Zimmermann M.

Leukemia. 1999 Mar;13(3):376-85.

PMID:
10086728
[PubMed - indexed for MEDLINE]
19.

Myelodysplastic and myeloproliferative disorders of childhood: a study of 167 patients.

Luna-Fineman S, Shannon KM, Atwater SK, Davis J, Masterson M, Ortega J, Sanders J, Steinherz P, Weinberg V, Lange BJ.

Blood. 1999 Jan 15;93(2):459-66.

PMID:
9885207
[PubMed - indexed for MEDLINE]
Free Article
20.

Mutant N-RAS induces erythroid lineage dysplasia in human CD34+ cells.

Darley RL, Hoy TG, Baines P, Padua RA, Burnett AK.

J Exp Med. 1997 Apr 7;185(7):1337-47.

PMID:
9104820
[PubMed - indexed for MEDLINE]
Free PMC Article

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