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Items: 1 to 20 of 56

1.

Identification of Raf-1 S471 as a novel phosphorylation site critical for Raf-1 and B-Raf kinase activities and for MEK binding.

Zhu J, Balan V, Bronisz A, Balan K, Sun H, Leicht DT, Luo Z, Qin J, Avruch J, Tzivion G.

Mol Biol Cell. 2005 Oct;16(10):4733-44. Epub 2005 Aug 10.

2.

Regulation of Raf-1 by direct feedback phosphorylation.

Dougherty MK, Müller J, Ritt DA, Zhou M, Zhou XZ, Copeland TD, Conrads TP, Veenstra TD, Lu KP, Morrison DK.

Mol Cell. 2005 Jan 21;17(2):215-24.

3.

Raf phosphorylation: one step forward and two steps back.

Dumaz N, Marais R.

Mol Cell. 2005 Jan 21;17(2):164-6.

4.

Novel C-Raf phosphorylation sites: serine 296 and 301 participate in Raf regulation.

Hekman M, Fischer A, Wennogle LP, Wang YK, Campbell SL, Rapp UR.

FEBS Lett. 2005 Jan 17;579(2):464-8.

5.

The RAF proteins take centre stage.

Wellbrock C, Karasarides M, Marais R.

Nat Rev Mol Cell Biol. 2004 Nov;5(11):875-85. Review.

PMID:
15520807
6.

V599EB-RAF is an oncogene in melanocytes.

Wellbrock C, Ogilvie L, Hedley D, Karasarides M, Martin J, Niculescu-Duvaz D, Springer CJ, Marais R.

Cancer Res. 2004 Apr 1;64(7):2338-42.

7.

Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF.

Wan PT, Garnett MJ, Roe SM, Lee S, Niculescu-Duvaz D, Good VM, Jones CM, Marshall CJ, Springer CJ, Barford D, Marais R; Cancer Genome Project.

Cell. 2004 Mar 19;116(6):855-67.

8.

Significance of 14-3-3 self-dimerization for phosphorylation-dependent target binding.

Shen YH, Godlewski J, Bronisz A, Zhu J, Comb MJ, Avruch J, Tzivion G.

Mol Biol Cell. 2003 Nov;14(11):4721-33. Epub 2003 Aug 7.

9.

Raf proteins and cancer: B-Raf is identified as a mutational target.

Mercer KE, Pritchard CA.

Biochim Biophys Acta. 2003 Jun 5;1653(1):25-40. Review.

PMID:
12781369
10.

Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors.

Shen YH, Godlewski J, Zhu J, Sathyanarayana P, Leaner V, Birrer MJ, Rana A, Tzivion G.

J Biol Chem. 2003 Jul 18;278(29):26715-21. Epub 2003 May 8.

11.

Mechanisms of regulating the Raf kinase family.

Chong H, Vikis HG, Guan KL.

Cell Signal. 2003 May;15(5):463-9. Review.

PMID:
12639709
12.

Untying the regulation of the Raf-1 kinase.

Dhillon AS, Kolch W.

Arch Biochem Biophys. 2002 Aug 1;404(1):3-9. Review.

PMID:
12127063
13.

Mutations of the BRAF gene in human cancer.

Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, Hall S, Hawes R, Hughes J, Kosmidou V, Menzies A, Mould C, Parker A, Stevens C, Watt S, Hooper S, Wilson R, Jayatilake H, Gusterson BA, Cooper C, Shipley J, Hargrave D, Pritchard-Jones K, Maitland N, Chenevix-Trench G, Riggins GJ, Bigner DD, Palmieri G, Cossu A, Flanagan A, Nicholson A, Ho JW, Leung SY, Yuen ST, Weber BL, Seigler HF, Darrow TL, Paterson H, Marais R, Marshall CJ, Wooster R, Stratton MR, Futreal PA.

Nature. 2002 Jun 27;417(6892):949-54. Epub 2002 Jun 9.

PMID:
12068308
14.

Identification of in vivo protein phosphorylation sites with mass spectrometry.

Qin J, Zhang X.

Methods Mol Biol. 2002;194:211-21. No abstract available.

PMID:
12029836
15.

Unraveling the complexities of the Raf/MAP kinase pathway for pharmacological intervention.

Herrera R, Sebolt-Leopold JS.

Trends Mol Med. 2002;8(4 Suppl):S27-31. Review. Erratum in: Trends Mol Med 2002 May;8(5):243.

PMID:
11927284
16.

Regulation of Raf-1 activation and signalling by dephosphorylation.

Dhillon AS, Meikle S, Yazici Z, Eulitz M, Kolch W.

EMBO J. 2002 Jan 15;21(1-2):64-71.

17.

14-3-3 proteins: active cofactors in cellular regulation by serine/threonine phosphorylation.

Tzivion G, Avruch J.

J Biol Chem. 2002 Feb 1;277(5):3061-4. Epub 2001 Nov 14. Review. No abstract available.

18.

14-3-3 proteins; bringing new definitions to scaffolding.

Tzivion G, Shen YH, Zhu J.

Oncogene. 2001 Oct 1;20(44):6331-8. Review.

19.
20.

Raf-1 without MEK?

Murakami MS, Morrison DK.

Sci STKE. 2001 Sep 11;2001(99):pe30.

PMID:
11579234
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