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Results: 1 to 20 of 45

1.

Induction of human endometrial cancer cell senescence through modulation of HIF-1alpha activity by EGLN1.

Kato H, Inoue T, Asanoma K, Nishimura C, Matsuda T, Wake N.

Int J Cancer. 2006 Mar 1;118(5):1144-53.

PMID:
16161047
[PubMed - indexed for MEDLINE]
2.

Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice.

Rankin EB, Higgins DF, Walisser JA, Johnson RS, Bradfield CA, Haase VH.

Mol Cell Biol. 2005 Apr;25(8):3163-72.

PMID:
15798202
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

VHL protein-interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF-1alpha.

Li Z, Wang D, Messing EM, Wu G.

EMBO Rep. 2005 Apr;6(4):373-8.

PMID:
15776016
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Congenital polycythemias/erythrocytoses.

Gordeuk VR, Stockton DW, Prchal JT.

Haematologica. 2005 Jan;90(1):109-16. Review.

PMID:
15642677
[PubMed - indexed for MEDLINE]
Free Article
5.

Mutations in the von Hippel-Lindau (VHL) tumor suppressor gene and VHL-haplotype analysis in patients with presumable congenital erythrocytosis.

Cario H, Schwarz K, Jorch N, Kyank U, Petrides PE, Schneider DT, Uhle R, Debatin KM, Kohne E.

Haematologica. 2005 Jan;90(1):19-24.

PMID:
15642664
[PubMed - indexed for MEDLINE]
Free Article
6.

HIF-2alpha regulates murine hematopoietic development in an erythropoietin-dependent manner.

Scortegagna M, Ding K, Zhang Q, Oktay Y, Bennett MJ, Bennett M, Shelton JM, Richardson JA, Moe O, Garcia JA.

Blood. 2005 Apr 15;105(8):3133-40. Epub 2004 Dec 30.

PMID:
15626745
[PubMed - indexed for MEDLINE]
Free Article
7.

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor.

Appelhoff RJ, Tian YM, Raval RR, Turley H, Harris AL, Pugh CW, Ratcliffe PJ, Gleadle JM.

J Biol Chem. 2004 Sep 10;279(37):38458-65. Epub 2004 Jul 7.

PMID:
15247232
[PubMed - indexed for MEDLINE]
Free Article
8.

Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells.

Warnecke C, Zaborowska Z, Kurreck J, Erdmann VA, Frei U, Wiesener M, Eckardt KU.

FASEB J. 2004 Sep;18(12):1462-4. Epub 2004 Jul 1.

PMID:
15240563
[PubMed - indexed for MEDLINE]
Free Article
9.

Congenital disorder of oxygen sensing: association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors.

Gordeuk VR, Sergueeva AI, Miasnikova GY, Okhotin D, Voloshin Y, Choyke PL, Butman JA, Jedlickova K, Prchal JT, Polyakova LA.

Blood. 2004 May 15;103(10):3924-32. Epub 2004 Jan 15.

PMID:
14726398
[PubMed - indexed for MEDLINE]
Free Article
10.

Tat-binding protein-1, a component of the 26S proteasome, contributes to the E3 ubiquitin ligase function of the von Hippel-Lindau protein.

Corn PG, McDonald ER 3rd, Herman JG, El-Deiry WS.

Nat Genet. 2003 Nov;35(3):229-37. Epub 2003 Oct 12.

PMID:
14556007
[PubMed - indexed for MEDLINE]
11.

Erythrocytosis and the Chuvash von Hippel-Lindau mutation.

Percy MJ, Beard ME, Carter C, Thein SL.

Br J Haematol. 2003 Oct;123(2):371-2. No abstract available.

PMID:
14531927
[PubMed - indexed for MEDLINE]
12.

A common polymorphism in the oxygen-dependent degradation (ODD) domain of hypoxia inducible factor-1alpha (HIF-1alpha) does not impair Pro-564 hydroxylation.

Percy MJ, Mooney SM, McMullin MF, Flores A, Lappin TR, Lee FS.

Mol Cancer. 2003 Sep 9;2:31.

PMID:
14521712
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Targeting HIF-1 for cancer therapy.

Semenza GL.

Nat Rev Cancer. 2003 Oct;3(10):721-32. Review.

PMID:
13130303
[PubMed - indexed for MEDLINE]
14.

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia.

Berra E, Benizri E, Ginouvès A, Volmat V, Roux D, Pouysségur J.

EMBO J. 2003 Aug 15;22(16):4082-90.

PMID:
12912907
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury.

Cai Z, Manalo DJ, Wei G, Rodriguez ER, Fox-Talbot K, Lu H, Zweier JL, Semenza GL.

Circulation. 2003 Jul 8;108(1):79-85. Epub 2003 Jun 9.

PMID:
12796124
[PubMed - indexed for MEDLINE]
Free Article
16.

Regulation of angiogenesis by hypoxia: role of the HIF system.

Pugh CW, Ratcliffe PJ.

Nat Med. 2003 Jun;9(6):677-84. Review.

PMID:
12778166
[PubMed - indexed for MEDLINE]
17.

The HIF family member EPAS1/HIF-2alpha is required for normal hematopoiesis in mice.

Scortegagna M, Morris MA, Oktay Y, Bennett M, Garcia JA.

Blood. 2003 Sep 1;102(5):1634-40. Epub 2003 May 15.

PMID:
12750163
[PubMed - indexed for MEDLINE]
Free Article
18.

Chuvash-type congenital polycythemia in 4 families of Asian and Western European ancestry.

Percy MJ, McMullin MF, Jowitt SN, Potter M, Treacy M, Watson WH, Lappin TR.

Blood. 2003 Aug 1;102(3):1097-9. Epub 2003 Apr 17.

PMID:
12702509
[PubMed - indexed for MEDLINE]
Free Article
19.

The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1alpha transcriptional activity.

Li Z, Wang D, Na X, Schoen SR, Messing EM, Wu G.

EMBO J. 2003 Apr 15;22(8):1857-67.

PMID:
12682018
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The transcriptional activity of the APP intracellular domain-Fe65 complex is inhibited by activation of the NF-kappaB pathway.

Zhao Q, Lee FS.

Biochemistry. 2003 Apr 1;42(12):3627-34.

PMID:
12653567
[PubMed - indexed for MEDLINE]

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