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Results: 1 to 20 of 42

1.

Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse.

Collier LS, Carlson CM, Ravimohan S, Dupuy AJ, Largaespada DA.

Nature. 2005 Jul 14;436(7048):272-6.

PMID:
16015333
[PubMed - indexed for MEDLINE]
Free Article
2.

Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system.

Dupuy AJ, Akagi K, Largaespada DA, Copeland NG, Jenkins NA.

Nature. 2005 Jul 14;436(7048):221-6.

PMID:
16015321
[PubMed - indexed for MEDLINE]
Free Article
3.

Phenotypic correction and long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon system.

Ohlfest JR, Frandsen JL, Fritz S, Lobitz PD, Perkinson SG, Clark KJ, Nelsestuen G, Key NS, McIvor RS, Hackett PB, Largaespada DA.

Blood. 2005 Apr 1;105(7):2691-8. Epub 2004 Dec 2.

PMID:
15576475
[PubMed - indexed for MEDLINE]
Free Article
4.

Mutational analysis of the N-terminal DNA-binding domain of sleeping beauty transposase: critical residues for DNA binding and hyperactivity in mammalian cells.

Yant SR, Park J, Huang Y, Mikkelsen JG, Kay MA.

Mol Cell Biol. 2004 Oct;24(20):9239-47.

PMID:
15456893
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Species- and cell type-specific requirements for cellular transformation.

Rangarajan A, Hong SJ, Gifford A, Weinberg RA.

Cancer Cell. 2004 Aug;6(2):171-83. Erratum in: Cancer Cell. 2013 Sep 9;24(3):394-8.

PMID:
15324700
[PubMed - indexed for MEDLINE]
6.

Transposon-based RNAi delivery system for generating knockdown cell lines.

Heggestad AD, Notterpek L, Fletcher BS.

Biochem Biophys Res Commun. 2004 Apr 9;316(3):643-50.

PMID:
15033448
[PubMed - indexed for MEDLINE]
7.

Characterization of Sleeping Beauty transposition and its application to genetic screening in mice.

Horie K, Yusa K, Yae K, Odajima J, Fischer SE, Keng VW, Hayakawa T, Mizuno S, Kondoh G, Ijiri T, Matsuda Y, Plasterk RH, Takeda J.

Mol Cell Biol. 2003 Dec;23(24):9189-207.

PMID:
14645530
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Transposon mutagenesis of the mouse germline.

Carlson CM, Dupuy AJ, Fritz S, Roberg-Perez KJ, Fletcher CF, Largaespada DA.

Genetics. 2003 Sep;165(1):243-56.

PMID:
14504232
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Gene insertion and long-term expression in lung mediated by the Sleeping Beauty transposon system.

Belur LR, Frandsen JL, Dupuy AJ, Ingbar DH, Largaespada DA, Hackett PB, Scott McIvor R.

Mol Ther. 2003 Sep;8(3):501-7.

PMID:
12946324
[PubMed - indexed for MEDLINE]
10.

Gene transfer into genomes of human cells by the sleeping beauty transposon system.

Geurts AM, Yang Y, Clark KJ, Liu G, Cui Z, Dupuy AJ, Bell JB, Largaespada DA, Hackett PB.

Mol Ther. 2003 Jul;8(1):108-17.

PMID:
12842434
[PubMed - indexed for MEDLINE]
11.

Transcription start regions in the human genome are favored targets for MLV integration.

Wu X, Li Y, Crise B, Burgess SM.

Science. 2003 Jun 13;300(5626):1749-51.

PMID:
12805549
[PubMed - indexed for MEDLINE]
Free Article
12.

In vivo correction of murine tyrosinemia type I by DNA-mediated transposition.

Montini E, Held PK, Noll M, Morcinek N, Al-Dhalimy M, Finegold M, Yant SR, Kay MA, Grompe M.

Mol Ther. 2002 Dec;6(6):759-69.

PMID:
12498772
[PubMed - indexed for MEDLINE]
13.

Common physical properties of DNA affecting target site selection of sleeping beauty and other Tc1/mariner transposable elements.

Vigdal TJ, Kaufman CD, Izsvák Z, Voytas DF, Ivics Z.

J Mol Biol. 2002 Oct 25;323(3):441-52.

PMID:
12381300
[PubMed - indexed for MEDLINE]
14.

Distinct requirements for Ras oncogenesis in human versus mouse cells.

Hamad NM, Elconin JH, Karnoub AE, Bai W, Rich JN, Abraham RT, Der CJ, Counter CM.

Genes Dev. 2002 Aug 15;16(16):2045-57. Review.

PMID:
12183360
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Induction of ovarian cancer by defined multiple genetic changes in a mouse model system.

Orsulic S, Li Y, Soslow RA, Vitale-Cross LA, Gutkind JS, Varmus HE.

Cancer Cell. 2002 Feb;1(1):53-62.

PMID:
12086888
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression.

Pelengaris S, Khan M, Evan GI.

Cell. 2002 May 3;109(3):321-34.

PMID:
12015982
[PubMed - indexed for MEDLINE]
17.

Conditional mouse models of sporadic cancer.

Jonkers J, Berns A.

Nat Rev Cancer. 2002 Apr;2(4):251-65. Review.

PMID:
12001987
[PubMed - indexed for MEDLINE]
18.

Mammalian germ-line transgenesis by transposition.

Dupuy AJ, Clark K, Carlson CM, Fritz S, Davidson AE, Markley KM, Finley K, Fletcher CF, Ekker SC, Hackett PB, Horn S, Largaespada DA.

Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4495-9. Epub 2002 Mar 19.

PMID:
11904379
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Cancer modeling in the modern era: progress and challenges.

Van Dyke T, Jacks T.

Cell. 2002 Jan 25;108(2):135-44. Review.

PMID:
11832204
[PubMed - indexed for MEDLINE]
20.

Efficient chromosomal transposition of a Tc1/mariner- like transposon Sleeping Beauty in mice.

Horie K, Kuroiwa A, Ikawa M, Okabe M, Kondoh G, Matsuda Y, Takeda J.

Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9191-6.

PMID:
11481482
[PubMed - indexed for MEDLINE]
Free PMC Article

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