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Items: 1 to 20 of 50

1.

Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase.

Feng J, Park J, Cron P, Hess D, Hemmings BA.

J Biol Chem. 2004 Sep 24;279(39):41189-96. Epub 2004 Jul 15.

2.

Unlocking the code of 14-3-3.

Dougherty MK, Morrison DK.

J Cell Sci. 2004 Apr 15;117(Pt 10):1875-84. Review.

3.

M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP.

Watanabe N, Arai H, Nishihara Y, Taniguchi M, Watanabe N, Hunter T, Osada H.

Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4419-24. Epub 2004 Mar 22.

4.

14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1).

Sekimoto T, Fukumoto M, Yoneda Y.

EMBO J. 2004 May 5;23(9):1934-42. Epub 2004 Apr 1.

5.

The 14-3-3 cancer connection.

Hermeking H.

Nat Rev Cancer. 2003 Dec;3(12):931-43. Review. No abstract available.

PMID:
14737123
6.

The decision to enter mitosis.

Dunphy WG.

Trends Cell Biol. 1994 Jun;4(6):202-7.

PMID:
14731678
7.

Molecular identification of Aggrus/T1alpha as a platelet aggregation-inducing factor expressed in colorectal tumors.

Kato Y, Fujita N, Kunita A, Sato S, Kaneko M, Osawa M, Tsuruo T.

J Biol Chem. 2003 Dec 19;278(51):51599-605. Epub 2003 Oct 1.

8.
9.

Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal.

Tsuruo T, Naito M, Tomida A, Fujita N, Mashima T, Sakamoto H, Haga N.

Cancer Sci. 2003 Jan;94(1):15-21. Review.

10.

Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy.

Chang F, Lee JT, Navolanic PM, Steelman LS, Shelton JG, Blalock WL, Franklin RA, McCubrey JA.

Leukemia. 2003 Mar;17(3):590-603. Review.

PMID:
12646949
11.

Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.

Rokudai S, Fujita N, Kitahara O, Nakamura Y, Tsuruo T.

Mol Cell Biol. 2002 Dec;22(24):8695-708.

12.

Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage.

Kandel ES, Skeen J, Majewski N, Di Cristofano A, Pandolfi PP, Feliciano CS, Gartel A, Hay N.

Mol Cell Biol. 2002 Nov;22(22):7831-41.

13.

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer.

Viglietto G, Motti ML, Bruni P, Melillo RM, D'Alessio A, Califano D, Vinci F, Chiappetta G, Tsichlis P, Bellacosa A, Fusco A, Santoro M.

Nat Med. 2002 Oct;8(10):1136-44. Epub 2002 Sep 16.

PMID:
12244303
14.

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest.

Liang J, Zubovitz J, Petrocelli T, Kotchetkov R, Connor MK, Han K, Lee JH, Ciarallo S, Catzavelos C, Beniston R, Franssen E, Slingerland JM.

Nat Med. 2002 Oct;8(10):1153-60. Epub 2002 Sep 16.

PMID:
12244302
15.

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization.

Shin I, Yakes FM, Rojo F, Shin NY, Bakin AV, Baselga J, Arteaga CL.

Nat Med. 2002 Oct;8(10):1145-52. Epub 2002 Sep 16.

PMID:
12244301
16.

Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function.

Basso AD, Solit DB, Chiosis G, Giri B, Tsichlis P, Rosen N.

J Biol Chem. 2002 Oct 18;277(42):39858-66. Epub 2002 Aug 9.

17.

Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization.

Fujita N, Sato S, Katayama K, Tsuruo T.

J Biol Chem. 2002 Aug 9;277(32):28706-13. Epub 2002 May 31.

18.

Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine).

Sato S, Fujita N, Tsuruo T.

Oncogene. 2002 Mar 7;21(11):1727-38.

19.

The PX domain: a new phosphoinositide-binding module.

Ellson CD, Andrews S, Stephens LR, Hawkins PT.

J Cell Sci. 2002 Mar 15;115(Pt 6):1099-105. Review. Erratum in: J Cell Sci 2002 May 1;115(Pt 9):1995.

20.

Apoptotic regulation by the Crk adapter protein mediated by interactions with Wee1 and Crm1/exportin.

Smith JJ, Richardson DA, Kopf J, Yoshida M, Hollingsworth RE, Kornbluth S.

Mol Cell Biol. 2002 Mar;22(5):1412-23.

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