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Items: 1 to 20 of 63


The distribution of the numbers of mutants in bacterial populations.


J Genet. 1949 Dec;49(3):264-85. No abstract available.


Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint.

Majka J, Burgers PM.

Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2249-54. Epub 2003 Feb 25.


Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro.

Bermudez VP, Lindsey-Boltz LA, Cesare AJ, Maniwa Y, Griffith JD, Hurwitz J, Sancar A.

Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1633-8. Epub 2003 Feb 10.


A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage.

Chang M, Bellaoui M, Boone C, Brown GW.

Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16934-9. Epub 2002 Dec 13.


Alternate pathways involving Sgs1/Top3, Mus81/ Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication.

Fabre F, Chan A, Heyer WD, Gangloff S.

Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16887-92. Epub 2002 Dec 10. Erratum in: Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1462.


Checking on the fork: the DNA-replication stress-response pathway.

Osborn AJ, Elledge SJ, Zou L.

Trends Cell Biol. 2002 Nov;12(11):509-16. Review.


Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.

Ayyagari R, Gomes XV, Gordenin DA, Burgers PM.

J Biol Chem. 2003 Jan 17;278(3):1618-25. Epub 2002 Nov 6.


Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects.

Sogo JM, Lopes M, Foiani M.

Science. 2002 Jul 26;297(5581):599-602.


Mus81-Eme1 and Rqh1 involvement in processing stalled and collapsed replication forks.

Doe CL, Ahn JS, Dixon J, Whitby MC.

J Biol Chem. 2002 Sep 6;277(36):32753-9. Epub 2002 Jun 25.


Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry.

Ho Y, Gruhler A, Heilbut A, Bader GD, Moore L, Adams SL, Millar A, Taylor P, Bennett K, Boutilier K, Yang L, Wolting C, Donaldson I, Schandorff S, Shewnarane J, Vo M, Taggart J, Goudreault M, Muskat B, Alfarano C, Dewar D, Lin Z, Michalickova K, Willems AR, Sassi H, Nielsen PA, Rasmussen KJ, Andersen JR, Johansen LE, Hansen LH, Jespersen H, Podtelejnikov A, Nielsen E, Crawford J, Poulsen V, Sørensen BD, Matthiesen J, Hendrickson RC, Gleeson F, Pawson T, Moran MF, Durocher D, Mann M, Hogue CW, Figeys D, Tyers M.

Nature. 2002 Jan 10;415(6868):180-3.


Functional organization of the yeast proteome by systematic analysis of protein complexes.

Gavin AC, Bösche M, Krause R, Grandi P, Marzioch M, Bauer A, Schultz J, Rick JM, Michon AM, Cruciat CM, Remor M, Höfert C, Schelder M, Brajenovic M, Ruffner H, Merino A, Klein K, Hudak M, Dickson D, Rudi T, Gnau V, Bauch A, Bastuck S, Huhse B, Leutwein C, Heurtier MA, Copley RR, Edelmann A, Querfurth E, Rybin V, Drewes G, Raida M, Bouwmeester T, Bork P, Seraphin B, Kuster B, Neubauer G, Superti-Furga G.

Nature. 2002 Jan 10;415(6868):141-7.


Systematic genetic analysis with ordered arrays of yeast deletion mutants.

Tong AH, Evangelista M, Parsons AB, Xu H, Bader GD, Pagé N, Robinson M, Raghibizadeh S, Hogue CW, Bussey H, Andrews B, Tyers M, Boone C.

Science. 2001 Dec 14;294(5550):2364-8.


Human Mus81-associated endonuclease cleaves Holliday junctions in vitro.

Chen XB, Melchionna R, Denis CM, Gaillard PH, Blasina A, Van de Weyer I, Boddy MN, Russell P, Vialard J, McGowan CH.

Mol Cell. 2001 Nov;8(5):1117-27.


The fuss about Mus81.

Haber JE, Heyer WD.

Cell. 2001 Nov 30;107(5):551-4. Review.


Okazaki fragment processing: modulation of the strand displacement activity of DNA polymerase delta by the concerted action of replication protein A, proliferating cell nuclear antigen, and flap endonuclease-1.

Maga G, Villani G, Tillement V, Stucki M, Locatelli GA, Frouin I, Spadari S, Hübscher U.

Proc Natl Acad Sci U S A. 2001 Dec 4;98(25):14298-303. Epub 2001 Nov 27.


Mus81-Eme1 are essential components of a Holliday junction resolvase.

Boddy MN, Gaillard PH, McDonald WH, Shanahan P, Yates JR 3rd, Russell P.

Cell. 2001 Nov 16;107(4):537-48.

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