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Results: 19

1.

The CCP4 suite: programs for protein crystallography.

Collaborative Computational Project, Number 4.

Acta Crystallogr D Biol Crystallogr. 1994 Sep 1;50(Pt 5):760-3.

PMID:
15299374
[PubMed]
2.

Calcineurin: from structure to function.

Aramburu J, Rao A, Klee CB.

Curr Top Cell Regul. 2000;36:237-95. Review. No abstract available.

PMID:
10842755
[PubMed - indexed for MEDLINE]
3.

Crystallography & NMR system: A new software suite for macromolecular structure determination.

Brünger AT, Adams PD, Clore GM, DeLano WL, Gros P, Grosse-Kunstleve RW, Jiang JS, Kuszewski J, Nilges M, Pannu NS, Read RJ, Rice LM, Simonson T, Warren GL.

Acta Crystallogr D Biol Crystallogr. 1998 Sep 1;54(Pt 5):905-21.

PMID:
9757107
[PubMed - indexed for MEDLINE]
4.

Overexpression and purification of human calcineurin alpha from Escherichia coli and assessment of catalytic functions of residues surrounding the binuclear metal center.

Mondragon A, Griffith EC, Sun L, Xiong F, Armstrong C, Liu JO.

Biochemistry. 1997 Apr 22;36(16):4934-42.

PMID:
9125515
[PubMed - indexed for MEDLINE]
5.

Calcineurin mutants render T lymphocytes resistant to cyclosporin A.

Zhu D, Cardenas ME, Heitman J.

Mol Pharmacol. 1996 Sep;50(3):506-11.

PMID:
8794888
[PubMed - indexed for MEDLINE]
6.

Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex.

Kissinger CR, Parge HE, Knighton DR, Lewis CT, Pelletier LA, Tempczyk A, Kalish VJ, Tucker KD, Showalter RE, Moomaw EW, et al.

Nature. 1995 Dec 7;378(6557):641-4.

PMID:
8524402
[PubMed - indexed for MEDLINE]
7.

X-ray structure of a decameric cyclophilin-cyclosporin crystal complex.

Pflügl G, Kallen J, Schirmer T, Jansonius JN, Zurini MG, Walkinshaw MD.

Nature. 1993 Jan 7;361(6407):91-4.

PMID:
8421501
[PubMed - indexed for MEDLINE]
8.

Solution structure of the cyclosporin A/cyclophilin complex by NMR.

Thériault Y, Logan TM, Meadows R, Yu L, Olejniczak ET, Holzman TF, Simmer RL, Fesik SW.

Nature. 1993 Jan 7;361(6407):88-91.

PMID:
8421500
[PubMed - indexed for MEDLINE]
9.

X-ray structure of a monomeric cyclophilin A-cyclosporin A crystal complex at 2.1 A resolution.

Mikol V, Kallen J, Pflügl G, Walkinshaw MD.

J Mol Biol. 1993 Dec 20;234(4):1119-30.

PMID:
8263916
[PubMed - indexed for MEDLINE]
10.

Structure-based design of a cyclophilin-calcineurin bridging ligand.

Alberg DG, Schreiber SL.

Science. 1993 Oct 8;262(5131):248-50.

PMID:
8211144
[PubMed - indexed for MEDLINE]
11.

Cyclophilin residues that affect noncompetitive inhibition of the protein serine phosphatase activity of calcineurin by the cyclophilin.cyclosporin A complex.

Etzkorn FA, Chang ZY, Stolz LA, Walsh CT.

Biochemistry. 1994 Mar 8;33(9):2380-8.

PMID:
8117697
[PubMed - indexed for MEDLINE]
12.

Cyclosporins. Structure-activity relationships.

Fliri H, Baumann G, Enz A, Kallen J, Luyten M, Mikol V, Movva R, Quesniaux V, Schreier M, Walkinshaw M, et al.

Ann N Y Acad Sci. 1993 Nov 30;696:47-53. Review.

PMID:
8109856
[PubMed - indexed for MEDLINE]
13.

Improved binding affinity for cyclophilin A by a cyclosporin derivative singly modified at its effector domain.

Papageorgiou C, Florineth A, Mikol V.

J Med Chem. 1994 Oct 28;37(22):3674-6. No abstract available.

PMID:
7966126
[PubMed - indexed for MEDLINE]
14.

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex.

Griffith JP, Kim JL, Kim EE, Sintchak MD, Thomson JA, Fitzgibbon MJ, Fleming MA, Caron PR, Hsiao K, Navia MA.

Cell. 1995 Aug 11;82(3):507-22.

PMID:
7543369
[PubMed - indexed for MEDLINE]
Free Article
15.

The latch region of calcineurin B is involved in both immunosuppressant-immunophilin complex docking and phosphatase activation.

Milan D, Griffith J, Su M, Price ER, McKeon F.

Cell. 1994 Nov 4;79(3):437-47.

PMID:
7525078
[PubMed - indexed for MEDLINE]
16.

Cloning, expression, and purification of human cyclophilin in Escherichia coli and assessment of the catalytic role of cysteines by site-directed mutagenesis.

Liu J, Albers MW, Chen CM, Schreiber SL, Walsh CT.

Proc Natl Acad Sci U S A. 1990 Mar;87(6):2304-8.

PMID:
2179953
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Improved methods for building protein models in electron density maps and the location of errors in these models.

Jones TA, Zou JY, Cowan SW, Kjeldgaard M.

Acta Crystallogr A. 1991 Mar 1;47 ( Pt 2):110-9.

PMID:
2025413
[PubMed - indexed for MEDLINE]
18.

Active site mutants of human cyclophilin A separate peptidyl-prolyl isomerase activity from cyclosporin A binding and calcineurin inhibition.

Zydowsky LD, Etzkorn FA, Chang HY, Ferguson SB, Stolz LA, Ho SI, Walsh CT.

Protein Sci. 1992 Sep;1(9):1092-9.

PMID:
1338979
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Cyclosporin-mediated inhibition of bovine calcineurin by cyclophilins A and B.

Swanson SK, Born T, Zydowsky LD, Cho H, Chang HY, Walsh CT, Rusnak F.

Proc Natl Acad Sci U S A. 1992 May 1;89(9):3741-5.

PMID:
1315036
[PubMed - indexed for MEDLINE]
Free PMC Article

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