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Results: 1 to 20 of 32

1.

Exploring protein aggregation and self-propagation using lattice models: phase diagram and kinetics.

Dima RI, Thirumalai D.

Protein Sci. 2002 May;11(5):1036-49.

PMID:
11967361
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Identification and characterization of key kinetic intermediates in amyloid beta-protein fibrillogenesis.

Kirkitadze MD, Condron MM, Teplow DB.

J Mol Biol. 2001 Oct 5;312(5):1103-19.

PMID:
11580253
[PubMed - indexed for MEDLINE]
3.

Probing the origins of increased activity of the E22Q "Dutch" mutant Alzheimer's beta-amyloid peptide.

Massi F, Straub JE.

Biophys J. 2001 Aug;81(2):697-709.

PMID:
11463618
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Conformational propagation with prion-like characteristics in a simple model of protein folding.

Harrison PM, Chan HS, Prusiner SB, Cohen FE.

Protein Sci. 2001 Apr;10(4):819-35.

PMID:
11274473
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Simulation study of the structure and dynamics of the Alzheimer's amyloid peptide congener in solution.

Massi F, Peng JW, Lee JP, Straub JE.

Biophys J. 2001 Jan;80(1):31-44.

PMID:
11159381
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Energy landscape theory for Alzheimer's amyloid beta-peptide fibril elongation.

Massi F, Straub JE.

Proteins. 2001 Feb 1;42(2):217-29.

PMID:
11119646
[PubMed - indexed for MEDLINE]
7.

Activation barriers to structural transition determine deposition rates of Alzheimer's disease a beta amyloid.

Esler WP, Felix AM, Stimson ER, Lachenmann MJ, Ghilardi JR, Lu YA, Vinters HV, Mantyh PW, Lee JP, Maggio JE.

J Struct Biol. 2000 Jun;130(2-3):174-83.

PMID:
10940224
[PubMed - indexed for MEDLINE]
8.

The Alzheimer's peptide a beta adopts a collapsed coil structure in water.

Zhang S, Iwata K, Lachenmann MJ, Peng JW, Li S, Stimson ER, Lu Y, Felix AM, Maggio JE, Lee JP.

J Struct Biol. 2000 Jun;130(2-3):130-41.

PMID:
10940221
[PubMed - indexed for MEDLINE]
9.

Oligomerization of beta-amyloid of the Alzheimer's and the Dutch-cerebral-haemorrhage types.

Sian AK, Frears ER, El-Agnaf OM, Patel BP, Manca MF, Siligardi G, Hussain R, Austen BM.

Biochem J. 2000 Jul 1;349(Pt 1):299-308.

PMID:
10861242
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Alzheimer's disease amyloid propagation by a template-dependent dock-lock mechanism.

Esler WP, Stimson ER, Jennings JM, Vinters HV, Ghilardi JR, Lee JP, Mantyh PW, Maggio JE.

Biochemistry. 2000 May 30;39(21):6288-95.

PMID:
10828941
[PubMed - indexed for MEDLINE]
11.

Substitutions at codon 22 of Alzheimer's abeta peptide induce diverse conformational changes and apoptotic effects in human cerebral endothelial cells.

Miravalle L, Tokuda T, Chiarle R, Giaccone G, Bugiani O, Tagliavini F, Frangione B, Ghiso J.

J Biol Chem. 2000 Sep 1;275(35):27110-6.

PMID:
10821838
[PubMed - indexed for MEDLINE]
Free Article
12.

Charge alterations of E22 enhance the pathogenic properties of the amyloid beta-protein.

Melchor JP, McVoy L, Van Nostrand WE.

J Neurochem. 2000 May;74(5):2209-12.

PMID:
10800967
[PubMed - indexed for MEDLINE]
13.

Unit-vector RMS (URMS) as a tool to analyze molecular dynamics trajectories.

Kedem K, Chew LP, Elber R.

Proteins. 1999 Dec 1;37(4):554-64.

PMID:
10651271
[PubMed - indexed for MEDLINE]
14.

Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates.

Walsh DM, Hartley DM, Kusumoto Y, Fezoui Y, Condron MM, Lomakin A, Benedek GB, Selkoe DJ, Teplow DB.

J Biol Chem. 1999 Sep 3;274(36):25945-52.

PMID:
10464339
[PubMed - indexed for MEDLINE]
Free Article
15.

Effects of the amyloid precursor protein Glu693-->Gln 'Dutch' mutation on the production and stability of amyloid beta-protein.

Watson DJ, Selkoe DJ, Teplow DB.

Biochem J. 1999 Jun 15;340 ( Pt 3):703-9.

PMID:
10359654
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Evolution of amyloid: what normal protein folding may tell us about fibrillogenesis and disease.

Lansbury PT Jr.

Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3342-4. Review. No abstract available.

PMID:
10097040
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Hydrophobic hydration of amphipathic peptides.

Cheng YK, Sheu WS, Rossky PJ.

Biophys J. 1999 Apr;76(4):1734-43.

PMID:
10096874
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Residual structure in the Alzheimer's disease peptide: probing the origin of a central hydrophobic cluster.

Zhang S, Casey N, Lee JP.

Fold Des. 1998;3(5):413-22.

PMID:
9806943
[PubMed - indexed for MEDLINE]
19.

Lattice models for proteins reveal multiple folding nuclei for nucleation-collapse mechanism.

Klimov DK, Thirumalai D.

J Mol Biol. 1998 Sep 18;282(2):471-92.

PMID:
9735420
[PubMed - indexed for MEDLINE]
20.

Structural and kinetic features of amyloid beta-protein fibrillogenesis.

Teplow DB.

Amyloid. 1998 Jun;5(2):121-42. Review.

PMID:
9686307
[PubMed - indexed for MEDLINE]

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