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Results: 1 to 20 of 45

1.

Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients.

Sakuraba H, Mizukami H, Yagihashi N, Wada R, Hanyu C, Yagihashi S.

Diabetologia. 2002 Jan;45(1):85-96.

PMID:
11845227
[PubMed - indexed for MEDLINE]
2.

Aging alters the apoptotic response to genotoxic stress.

Suh Y, Lee KA, Kim WH, Han BG, Vijg J, Park SC.

Nat Med. 2002 Jan;8(1):3-4. No abstract available.

PMID:
11786880
[PubMed - indexed for MEDLINE]
3.

Current and future treatment strategies for type 2 diabetes: the beta-cell as a therapeutic target.

Tyrberg B, Levine F.

Curr Opin Investig Drugs. 2001 Nov;2(11):1568-74. Review.

PMID:
11763159
[PubMed - indexed for MEDLINE]
5.

Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells.

Lakey JR, Suarez-Pinzon WL, Strynadka K, Korbutt GS, Rajotte RV, Mabley JG, Szabó C, Rabinovitch A.

Lab Invest. 2001 Dec;81(12):1683-92.

PMID:
11742038
[PubMed - indexed for MEDLINE]
6.

Age-related and tissue-specific accumulation of oxidative DNA base damage in 7,8-dihydro-8-oxoguanine-DNA glycosylase (Ogg1) deficient mice.

Osterod M, Hollenbach S, Hengstler JG, Barnes DE, Lindahl T, Epe B.

Carcinogenesis. 2001 Sep;22(9):1459-63.

PMID:
11532868
[PubMed - indexed for MEDLINE]
Free Article
7.

Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation.

Cnop M, Hannaert JC, Hoorens A, Eizirik DL, Pipeleers DG.

Diabetes. 2001 Aug;50(8):1771-7.

PMID:
11473037
[PubMed - indexed for MEDLINE]
Free Article
8.

Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets.

Maedler K, Spinas GA, Lehmann R, Sergeev P, Weber M, Fontana A, Kaiser N, Donath MY.

Diabetes. 2001 Aug;50(8):1683-90.

PMID:
11473025
[PubMed - indexed for MEDLINE]
Free Article
9.

Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice.

de Souza-Pinto NC, Eide L, Hogue BA, Thybo T, Stevnsner T, Seeberg E, Klungland A, Bohr VA.

Cancer Res. 2001 Jul 15;61(14):5378-81.

PMID:
11454679
[PubMed - indexed for MEDLINE]
Free Article
10.

Enhancement of OGG1 protein AP lyase activity by increase of APEX protein.

Saitoh T, Shinmura K, Yamaguchi S, Tani M, Seki S, Murakami H, Nojima Y, Yokota J.

Mutat Res. 2001 Jun 5;486(1):31-40.

PMID:
11356334
[PubMed - indexed for MEDLINE]
11.

Species differences in susceptibility of transplanted and cultured pancreatic islets to the beta-cell toxin alloxan.

Tyrberg B, Andersson A, Borg LA.

Gen Comp Endocrinol. 2001 Jun;122(3):238-51.

PMID:
11356036
[PubMed - indexed for MEDLINE]
12.

DNA repair and aging in mouse liver: 8-oxodG glycosylase activity increase in mitochondrial but not in nuclear extracts.

de Souza-Pinto NC, Hogue BA, Bohr VA.

Free Radic Biol Med. 2001 Apr 15;30(8):916-23.

PMID:
11295534
[PubMed - indexed for MEDLINE]
13.

Advanced glycation end-products: a review.

Singh R, Barden A, Mori T, Beilin L.

Diabetologia. 2001 Feb;44(2):129-46. Review. Erratum in: Diabetologia 2002 Feb;45(2):293.

PMID:
11270668
[PubMed - indexed for MEDLINE]
14.

Diabetes: statins, fibrates, or both?

Farnier M, Picard S.

Curr Atheroscler Rep. 2001 Jan;3(1):19-28. Review.

PMID:
11123844
[PubMed - indexed for MEDLINE]
15.

Leishmania antigen nonspecific binding to avidin in biotin-avidin immunoassays.

Agudelo S, Portús M.

Clin Diagn Lab Immunol. 2000 Jul;7(4):717-8. No abstract available.

PMID:
10991608
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Islet amyloid and type 2 diabetes mellitus.

Höppener JW, Ahrén B, Lips CJ.

N Engl J Med. 2000 Aug 10;343(6):411-9. Review. No abstract available.

PMID:
10933741
[PubMed - indexed for MEDLINE]
17.

Detection of 8-oxoG DNA glycosylase activity and OGG1 transcripts in the rat CNS.

Verjat T, Dhénaut A, Radicella JP, Araneda S.

Mutat Res. 2000 Jul 25;460(2):127-38.

PMID:
10882853
[PubMed - indexed for MEDLINE]
18.

Up-regulation of base excision repair activity for 8-hydroxy-2'-deoxyguanosine in the mouse brain after forebrain ischemia-reperfusion.

Lin LH, Cao S, Yu L, Cui J, Hamilton WJ, Liu PK.

J Neurochem. 2000 Mar;74(3):1098-105.

PMID:
10693941
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Somatic mutations and aging: a re-evaluation.

Vijg J.

Mutat Res. 2000 Jan 17;447(1):117-35. Review.

PMID:
10686308
[PubMed - indexed for MEDLINE]
20.

Regulation of energy metabolism in human cells in aging and diabetes: FoF(1), mtDNA, UCP, and ROS.

Kagawa Y, Cha SH, Hasegawa K, Hamamoto T, Endo H.

Biochem Biophys Res Commun. 1999 Dec 29;266(3):662-76. Review.

PMID:
10603304
[PubMed - indexed for MEDLINE]

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