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Results: 1 to 20 of 62

1.

CARNITINE ACETYLTRANSFERASE. II. INHIBIITON BY CARNITINE ANALOGUES AND BY SULFHYDRYL REAGENTS.

FRITZ IB, SCHULTZ SK.

J Biol Chem. 1965 May;240:2188-92. No abstract available.

PMID:
14299645
[PubMed - indexed for MEDLINE]
Free Article
2.

Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites.

Liu J, Atamna H, Kuratsune H, Ames BN.

Ann N Y Acad Sci. 2002 Apr;959:133-66. Review.

PMID:
11976193
[PubMed - indexed for MEDLINE]
3.

Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid.

Liu J, Head E, Gharib AM, Yuan W, Ingersoll RT, Hagen TM, Cotman CW, Ames BN.

Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2356-61. Erratum in: Proc Natl Acad Sci U S A 2002 May 14;99(10):7184-5.

PMID:
11854529
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress.

Hagen TM, Liu J, Lykkesfeldt J, Wehr CM, Ingersoll RT, Vinarsky V, Bartholomew JC, Ames BN.

Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1870-5. Erratum in: Proc Natl Acad Sci U S A 2002 May 14;99(10):7184.

PMID:
11854487
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Alpha-lipoic acid and alpha-lipoamide prevent oxidant-induced lysosomal rupture and apoptosis.

Persson HL, Svensson AI, Brunk UT.

Redox Rep. 2001;6(5):327-34.

PMID:
11778851
[PubMed - indexed for MEDLINE]
6.

Proteasomes and proteasome inhibition in the central nervous system.

Ding Q, Keller JN.

Free Radic Biol Med. 2001 Sep 1;31(5):574-84. Review.

PMID:
11522442
[PubMed - indexed for MEDLINE]
7.

Garbage catastrophe theory of aging: imperfect removal of oxidative damage?

Terman A.

Redox Rep. 2001;6(1):15-26. Review.

PMID:
11333111
[PubMed - indexed for MEDLINE]
8.

Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid.

Suh JH, Shigeno ET, Morrow JD, Cox B, Rocha AE, Frei B, Hagen TM.

FASEB J. 2001 Mar;15(3):700-6.

PMID:
11259388
[PubMed - indexed for MEDLINE]
Free Article
9.

(R)-alpha-lipoic acid reverses the age-associated increase in susceptibility of hepatocytes to tert-butylhydroperoxide both in vitro and in vivo.

Hagen TM, Vinarsky V, Wehr CM, Ames BN.

Antioxid Redox Signal. 2000 Fall;2(3):473-83.

PMID:
11229361
[PubMed - indexed for MEDLINE]
10.

Age-related changes in LTP and antioxidant defenses are reversed by an alpha-lipoic acid-enriched diet.

McGahon BM, Martin DS, Horrobin DF, Lynch MA.

Neurobiol Aging. 1999 Nov-Dec;20(6):655-64.

PMID:
10674431
[PubMed - indexed for MEDLINE]
11.

Carnitine acyltransferases: functional significance of subcellular distribution and membrane topology.

Zammit VA.

Prog Lipid Res. 1999 May;38(3):199-224. Review. No abstract available.

PMID:
10664793
[PubMed - indexed for MEDLINE]
12.

Muscle carnitine acetyltransferase and carnitine deficiency in a case of mitochondrial encephalomyopathy.

Melegh B, Seress L, Bedekovics T, Kispál G, Sümegi B, Trombitás K, Méhes K.

J Inherit Metab Dis. 1999 Oct;22(7):827-38.

PMID:
10518284
[PubMed - indexed for MEDLINE]
13.

The effect of aging and acetyl-L-carnitine on the pyruvate transport and oxidation in rat heart mitochondria.

Paradies G, Petrosillo G, Gadaleta MN, Ruggiero FM.

FEBS Lett. 1999 Jul 9;454(3):207-9.

PMID:
10431808
[PubMed - indexed for MEDLINE]
Free Article
14.

Micronutrients prevent cancer and delay aging.

Ames BN.

Toxicol Lett. 1998 Dec 28;102-103:5-18. Review.

PMID:
10022226
[PubMed - indexed for MEDLINE]
15.

(R)-alpha-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate.

Hagen TM, Ingersoll RT, Lykkesfeldt J, Liu J, Wehr CM, Vinarsky V, Bartholomew JC, Ames AB.

FASEB J. 1999 Feb;13(2):411-8.

PMID:
9973329
[PubMed - indexed for MEDLINE]
Free Article
16.

Mitochondrial decay in aging. Reversal through supplementation of acetyl-L-carnitine and N-tert-butyl-alpha-phenyl-nitrone.

Hagen TM, Wehr CM, Ames BN.

Ann N Y Acad Sci. 1998 Nov 20;854:214-23.

PMID:
9928432
[PubMed - indexed for MEDLINE]
17.

The effects of dietary restriction on mitochondrial dysfunction in aging.

Feuers RJ.

Ann N Y Acad Sci. 1998 Nov 20;854:192-201.

PMID:
9928430
[PubMed - indexed for MEDLINE]
18.

Assay of malondialdehyde and other alkanals in biological fluids by gas chromatography-mass spectrometry.

Yeo HC, Liu J, Helbock HJ, Ames BN.

Methods Enzymol. 1999;300:70-8.

PMID:
9919511
[PubMed - indexed for MEDLINE]
19.

Selective inactivation of alpha-ketoglutarate dehydrogenase and pyruvate dehydrogenase: reaction of lipoic acid with 4-hydroxy-2-nonenal.

Humphries KM, Szweda LI.

Biochemistry. 1998 Nov 10;37(45):15835-41.

PMID:
9843389
[PubMed - indexed for MEDLINE]
20.

Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes--reversal with (R)-alpha-lipoic acid supplementation.

Lykkesfeldt J, Hagen TM, Vinarsky V, Ames BN.

FASEB J. 1998 Sep;12(12):1183-9.

PMID:
9737721
[PubMed - indexed for MEDLINE]
Free Article

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