Format
Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 99

1.
2.

Geldanamycin induces cell cycle arrest in K562 erythroleukemic cells.

Kim HR, Lee CH, Choi YH, Kang HS, Kim HD.

IUBMB Life. 1999 Oct;48(4):425-8.

3.

The stabilization mechanism of mutant-type p53 by impaired ubiquitination: the loss of wild-type p53 function and the hsp90 association.

Nagata Y, Anan T, Yoshida T, Mizukami T, Taya Y, Fujiwara T, Kato H, Saya H, Nakao M.

Oncogene. 1999 Oct 28;18(44):6037-49.

4.

A novel chaperone-activity-reducing mechanism of the 90-kDa molecular chaperone HSP90.

Itoh H, Ogura M, Komatsuda A, Wakui H, Miura AB, Tashima Y.

Biochem J. 1999 Nov 1;343 Pt 3:697-703.

5.

Interaction of radicicol with members of the heat shock protein 90 family of molecular chaperones.

Schulte TW, Akinaga S, Murakata T, Agatsuma T, Sugimoto S, Nakano H, Lee YS, Simen BB, Argon Y, Felts S, Toft DO, Neckers LM, Sharma SV.

Mol Endocrinol. 1999 Sep;13(9):1435-48.

PMID:
10478836
6.
7.

KF25706, a novel oxime derivative of radicicol, exhibits in vivo antitumor activity via selective depletion of Hsp90 binding signaling molecules.

Soga S, Neckers LM, Schulte TW, Shiotsu Y, Akasaka K, Narumi H, Agatsuma T, Ikuina Y, Murakata C, Tamaoki T, Akinaga S.

Cancer Res. 1999 Jun 15;59(12):2931-8.

8.

Heat shock protein 90 mediates macrophage activation by Taxol and bacterial lipopolysaccharide.

Byrd CA, Bornmann W, Erdjument-Bromage H, Tempst P, Pavletich N, Rosen N, Nathan CF, Ding A.

Proc Natl Acad Sci U S A. 1999 May 11;96(10):5645-50.

9.

Functional requirement of p23 and Hsp90 in telomerase complexes.

Holt SE, Aisner DL, Baur J, Tesmer VM, Dy M, Ouellette M, Trager JB, Morin GB, Toft DO, Shay JW, Wright WE, White MA.

Genes Dev. 1999 Apr 1;13(7):817-26.

10.

The charged region of Hsp90 modulates the function of the N-terminal domain.

Scheibel T, Siegmund HI, Jaenicke R, Ganz P, Lilie H, Buchner J.

Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1297-302.

11.

The benzoquinone ansamycin geldanamycin stimulates proteolytic degradation of focal adhesion kinase.

Ochel HJ, Schulte TW, Nguyen P, Trepel J, Neckers L.

Mol Genet Metab. 1999 Jan;66(1):24-30.

PMID:
9973544
12.

Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin.

Roe SM, Prodromou C, O'Brien R, Ladbury JE, Piper PW, Pearl LH.

J Med Chem. 1999 Jan 28;42(2):260-6.

PMID:
9925731
13.

Hsp90 as a capacitor for morphological evolution.

Rutherford SL, Lindquist S.

Nature. 1998 Nov 26;396(6709):336-42.

PMID:
9845070
15.

In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis.

Obermann WM, Sondermann H, Russo AA, Pavletich NP, Hartl FU.

J Cell Biol. 1998 Nov 16;143(4):901-10.

16.
17.

ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo.

Panaretou B, Prodromou C, Roe SM, O'Brien R, Ladbury JE, Piper PW, Pearl LH.

EMBO J. 1998 Aug 17;17(16):4829-36.

18.

Antibiotic radicicol binds to the N-terminal domain of Hsp90 and shares important biologic activities with geldanamycin.

Schulte TW, Akinaga S, Soga S, Sullivan W, Stensgard B, Toft D, Neckers LM.

Cell Stress Chaperones. 1998 Jun;3(2):100-8.

19.

The physical association of multiple molecular chaperone proteins with mutant p53 is altered by geldanamycin, an hsp90-binding agent.

Whitesell L, Sutphin PD, Pulcini EJ, Martinez JD, Cook PH.

Mol Cell Biol. 1998 Mar;18(3):1517-24.

20.

Geldanamycin prevents nuclear translocation of mutant p53.

Dasgupta G, Momand J.

Exp Cell Res. 1997 Nov 25;237(1):29-37.

PMID:
9417863
Items per page

Supplemental Content

Write to the Help Desk