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Results: 1 to 20 of 68

1.

Expression of hypoxia-inducible factor-1alpha: a novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer.

Aebersold DM, Burri P, Beer KT, Laissue J, Djonov V, Greiner RH, Semenza GL.

Cancer Res. 2001 Apr 1;61(7):2911-6.

PMID:
11306467
[PubMed - indexed for MEDLINE]
Free Article
2.

Levels of hypoxia-inducible factor-1 alpha during breast carcinogenesis.

Bos R, Zhong H, Hanrahan CF, Mommers EC, Semenza GL, Pinedo HM, Abeloff MD, Simons JW, van Diest PJ, van der Wall E.

J Natl Cancer Inst. 2001 Feb 21;93(4):309-14.

PMID:
11181778
[PubMed - indexed for MEDLINE]
Free Article
3.

Regulated translation initiation controls stress-induced gene expression in mammalian cells.

Harding HP, Novoa I, Zhang Y, Zeng H, Wek R, Schapira M, Ron D.

Mol Cell. 2000 Nov;6(5):1099-108.

PMID:
11106749
[PubMed - indexed for MEDLINE]
Free Article
4.

Suppression of tumor growth through disruption of hypoxia-inducible transcription.

Kung AL, Wang S, Klco JM, Kaelin WG, Livingston DM.

Nat Med. 2000 Dec;6(12):1335-40.

PMID:
11100117
[PubMed - indexed for MEDLINE]
5.

Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer.

Salnikow K, Costa M, Figg WD, Blagosklonny MV.

Cancer Res. 2000 Oct 15;60(20):5630-4.

PMID:
11059752
[PubMed - indexed for MEDLINE]
Free Article
6.

Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer.

Birner P, Schindl M, Obermair A, Plank C, Breitenecker G, Oberhuber G.

Cancer Res. 2000 Sep 1;60(17):4693-6.

PMID:
10987269
[PubMed - indexed for MEDLINE]
Free Article
7.

Vascular endothelial growth factor up-regulation via p21-activated kinase-1 signaling regulates heregulin-beta1-mediated angiogenesis.

Bagheri-Yarmand R, Vadlamudi RK, Wang RA, Mendelsohn J, Kumar R.

J Biol Chem. 2000 Dec 15;275(50):39451-7.

PMID:
10967114
[PubMed - indexed for MEDLINE]
Free Article
8.

Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth.

Ryan HE, Poloni M, McNulty W, Elson D, Gassmann M, Arbeit JM, Johnson RS.

Cancer Res. 2000 Aug 1;60(15):4010-5.

PMID:
10945599
[PubMed - indexed for MEDLINE]
Free Article
9.

Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein.

Tanimoto K, Makino Y, Pereira T, Poellinger L.

EMBO J. 2000 Aug 15;19(16):4298-309.

PMID:
10944113
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages.

Talks KL, Turley H, Gatter KC, Maxwell PH, Pugh CW, Ratcliffe PJ, Harris AL.

Am J Pathol. 2000 Aug;157(2):411-21.

PMID:
10934146
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis.

Yen L, You XL, Al Moustafa AE, Batist G, Hynes NE, Mader S, Meloche S, Alaoui-Jamali MA.

Oncogene. 2000 Jul 20;19(31):3460-9.

PMID:
10918604
[PubMed - indexed for MEDLINE]
Free Article
12.

Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression.

Zagzag D, Zhong H, Scalzitti JM, Laughner E, Simons JW, Semenza GL.

Cancer. 2000 Jun 1;88(11):2606-18.

PMID:
10861440
[PubMed - indexed for MEDLINE]
13.

Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells.

Richard DE, Berra E, Pouyssegur J.

J Biol Chem. 2000 Sep 1;275(35):26765-71.

PMID:
10837481
[PubMed - indexed for MEDLINE]
Free Article
14.

Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein.

Cockman ME, Masson N, Mole DR, Jaakkola P, Chang GW, Clifford SC, Maher ER, Pugh CW, Ratcliffe PJ, Maxwell PH.

J Biol Chem. 2000 Aug 18;275(33):25733-41.

PMID:
10823831
[PubMed - indexed for MEDLINE]
Free Article
15.

Hypoxia, clonal selection, and the role of HIF-1 in tumor progression.

Semenza GL.

Crit Rev Biochem Mol Biol. 2000;35(2):71-103. Review.

PMID:
10821478
[PubMed - indexed for MEDLINE]
16.

Hypoxia-inducible factor 1alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations.

Sutter CH, Laughner E, Semenza GL.

Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4748-53.

PMID:
10758161
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics.

Zhong H, Chiles K, Feldser D, Laughner E, Hanrahan C, Georgescu MM, Simons JW, Semenza GL.

Cancer Res. 2000 Mar 15;60(6):1541-5.

PMID:
10749120
[PubMed - indexed for MEDLINE]
Free Article
18.

Correlation of vascular endothelial growth factor content with recurrences, survival, and first relapse site in primary node-positive breast carcinoma after adjuvant treatment.

Linderholm B, Grankvist K, Wilking N, Johansson M, Tavelin B, Henriksson R.

J Clin Oncol. 2000 Apr;18(7):1423-31.

PMID:
10735889
[PubMed - indexed for MEDLINE]
19.

HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway.

Zhou BP, Hu MC, Miller SA, Yu Z, Xia W, Lin SY, Hung MC.

J Biol Chem. 2000 Mar 17;275(11):8027-31.

PMID:
10713122
[PubMed - indexed for MEDLINE]
Free Article
20.

Loss of PTEN facilitates HIF-1-mediated gene expression.

Zundel W, Schindler C, Haas-Kogan D, Koong A, Kaper F, Chen E, Gottschalk AR, Ryan HE, Johnson RS, Jefferson AB, Stokoe D, Giaccia AJ.

Genes Dev. 2000 Feb 15;14(4):391-6.

PMID:
10691731
[PubMed - indexed for MEDLINE]
Free PMC Article

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