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Items: 1 to 20 of 28


Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis.

Daugas E, Susin SA, Zamzami N, Ferri KF, Irinopoulou T, Larochette N, Prévost MC, Leber B, Andrews D, Penninger J, Kroemer G.

FASEB J. 2000 Apr;14(5):729-39.


Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation.

Sahara S, Aoto M, Eguchi Y, Imamoto N, Yoneda Y, Tsujimoto Y.

Nature. 1999 Sep 9;401(6749):168-73.


Apoptotic nuclear morphological change without DNA fragmentation.

Sakahira H, Enari M, Ohsawa Y, Uchiyama Y, Nagata S.

Curr Biol. 1999 May 20;9(10):543-6.


Molecular characterization of mitochondrial apoptosis-inducing factor.

Susin SA, Lorenzo HK, Zamzami N, Marzo I, Snow BE, Brothers GM, Mangion J, Jacotot E, Costantini P, Loeffler M, Larochette N, Goodlett DR, Aebersold R, Siderovski DP, Penninger JM, Kroemer G.

Nature. 1999 Feb 4;397(6718):441-6.


In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system.

Srinivasan A, Roth KA, Sayers RO, Shindler KS, Wong AM, Fritz LC, Tomaselli KJ.

Cell Death Differ. 1998 Dec;5(12):1004-16.


Mitochondrial release of caspase-2 and -9 during the apoptotic process.

Susin SA, Lorenzo HK, Zamzami N, Marzo I, Brenner C, Larochette N, Prévost MC, Alzari PM, Kroemer G.

J Exp Med. 1999 Jan 18;189(2):381-94.


Caspase-3 controls both cytoplasmic and nuclear events associated with Fas-mediated apoptosis in vivo.

Zheng TS, Schlosser SF, Dao T, Hingorani R, Crispe IN, Boyer JL, Flavell RA.

Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13618-23.


PML induces a novel caspase-independent death process.

Quignon F, De Bels F, Koken M, Feunteun J, Ameisen JC, de Thé H.

Nat Genet. 1998 Nov;20(3):259-65.


CXCR4 and CD4 mediate a rapid CD95-independent cell death in CD4(+) T cells.

Berndt C, Möpps B, Angermüller S, Gierschik P, Krammer PH.

Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12556-61.


Transition from caspase-dependent to caspase-independent mechanisms at the onset of apoptotic execution.

Samejima K, Toné S, Kottke TJ, Enari M, Sakahira H, Cooke CA, Durrieu F, Martins LM, Nagata S, Kaufmann SH, Earnshaw WC.

J Cell Biol. 1998 Oct 5;143(1):225-39.


Caspase-independent cell death induced by anti-CD2 or staurosporine in activated human peripheral T lymphocytes.

Déas O, Dumont C, MacFarlane M, Rouleau M, Hebib C, Harper F, Hirsch F, Charpentier B, Cohen GM, Senik A.

J Immunol. 1998 Oct 1;161(7):3375-83.


Apaf1 is required for mitochondrial pathways of apoptosis and brain development.

Yoshida H, Kong YY, Yoshida R, Elia AJ, Hakem A, Hakem R, Penninger JM, Mak TW.

Cell. 1998 Sep 18;94(6):739-50.


Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis.

Marzo I, Brenner C, Zamzami N, Jürgensmeier JM, Susin SA, Vieira HL, Prévost MC, Xie Z, Matsuyama S, Reed JC, Kroemer G.

Science. 1998 Sep 25;281(5385):2027-31.


The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis.

Liu X, Li P, Widlak P, Zou H, Luo X, Garrard WT, Wang X.

Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8461-6.


Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes.

Woo M, Hakem R, Soengas MS, Duncan GS, Shahinian A, Kägi D, Hakem A, McCurrach M, Khoo W, Kaufman SA, Senaldi G, Howard T, Lowe SW, Mak TW.

Genes Dev. 1998 Mar 15;12(6):806-19.


Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis.

Sakahira H, Enari M, Nagata S.

Nature. 1998 Jan 1;391(6662):96-9.


A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD.

Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S.

Nature. 1998 Jan 1;391(6662):43-50. Erratum in: Nature 1998 May 28;393(6683):396.


The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death.

Hirsch T, Marchetti P, Susin SA, Dallaporta B, Zamzami N, Marzo I, Geuskens M, Kroemer G.

Oncogene. 1997 Sep 25;15(13):1573-81.


The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis.

Susin SA, Zamzami N, Castedo M, Daugas E, Wang HG, Geley S, Fassy F, Reed JC, Kroemer G.

J Exp Med. 1997 Jul 7;186(1):25-37.

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