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Items: 1 to 20 of 65

1.

On the Role of ATP-Gated P2X Receptors in Acute, Inflammatory and Neuropathic Pain.

Toulme E, Tsuda M, Khakh BS, Inoue K.

In: Kruger L, Light AR, editors. Translational Pain Research: From Mouse to Man. Boca Raton, FL: CRC Press/Taylor & Francis; 2010. Chapter 10.

2.
3.

Up-regulation of P2X4 receptors in spinal microglia after peripheral nerve injury mediates BDNF release and neuropathic pain.

Ulmann L, Hatcher JP, Hughes JP, Chaumont S, Green PJ, Conquet F, Buell GN, Reeve AJ, Chessell IP, Rassendren F.

J Neurosci. 2008 Oct 29;28(44):11263-8. doi: 10.1523/JNEUROSCI.2308-08.2008.

4.

Fibronectin/integrin system is involved in P2X(4) receptor upregulation in the spinal cord and neuropathic pain after nerve injury.

Tsuda M, Toyomitsu E, Komatsu T, Masuda T, Kunifusa E, Nasu-Tada K, Koizumi S, Yamamoto K, Ando J, Inoue K.

Glia. 2008 Apr;56(5):579-85. doi: 10.1002/glia.20641.

PMID:
18240312
5.

Regulation of P2X4 receptors by lysosomal targeting, glycan protection and exocytosis.

Qureshi OS, Paramasivam A, Yu JC, Murrell-Lagnado RD.

J Cell Sci. 2007 Nov 1;120(Pt 21):3838-49. Epub 2007 Oct 16.

6.

Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury.

Tsuda M, Tozaki-Saitoh H, Masuda T, Toyomitsu E, Tezuka T, Yamamoto T, Inoue K.

Glia. 2008 Jan 1;56(1):50-8.

PMID:
17918263
7.

Characterization of a selective and potent antagonist of human P2X(7) receptors, AZ11645373.

Stokes L, Jiang LH, Alcaraz L, Bent J, Bowers K, Fagura M, Furber M, Mortimore M, Lawson M, Theaker J, Laurent C, Braddock M, Surprenant A.

Br J Pharmacol. 2006 Dec;149(7):880-7. Epub 2006 Oct 9.

8.

A-740003 [N-(1-{[(cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a novel and selective P2X7 receptor antagonist, dose-dependently reduces neuropathic pain in the rat.

Honore P, Donnelly-Roberts D, Namovic MT, Hsieh G, Zhu CZ, Mikusa JP, Hernandez G, Zhong C, Gauvin DM, Chandran P, Harris R, Medrano AP, Carroll W, Marsh K, Sullivan JP, Faltynek CR, Jarvis MF.

J Pharmacol Exp Ther. 2006 Dec;319(3):1376-85. Epub 2006 Sep 18.

9.

Combinations of TLR and NOD2 ligands stimulate rat microglial P2X4R expression.

Guo LH, Guo KT, Wendel HP, Schluesener HJ.

Biochem Biophys Res Commun. 2006 Oct 27;349(3):1156-62. Epub 2006 Sep 1.

PMID:
16973131
10.

P2X receptors as cell-surface ATP sensors in health and disease.

Khakh BS, North RA.

Nature. 2006 Aug 3;442(7102):527-32. Review.

PMID:
16885977
12.

BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain.

Coull JA, Beggs S, Boudreau D, Boivin D, Tsuda M, Inoue K, Gravel C, Salter MW, De Koninck Y.

Nature. 2005 Dec 15;438(7070):1017-21.

PMID:
16355225
13.

Interleukin-1alphabeta gene-deficient mice show reduced nociceptive sensitivity in models of inflammatory and neuropathic pain but not post-operative pain.

Honore P, Wade CL, Zhong C, Harris RR, Wu C, Ghayur T, Iwakura Y, Decker MW, Faltynek C, Sullivan J, Jarvis MF.

Behav Brain Res. 2006 Feb 28;167(2):355-64. Epub 2005 Oct 26.

PMID:
16256210
14.

The function of microglia through purinergic receptors: neuropathic pain and cytokine release.

Inoue K.

Pharmacol Ther. 2006 Jan;109(1-2):210-26. Epub 2005 Sep 19. Review.

PMID:
16169595
15.

Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain.

Chessell IP, Hatcher JP, Bountra C, Michel AD, Hughes JP, Green P, Egerton J, Murfin M, Richardson J, Peck WL, Grahames CB, Casula MA, Yiangou Y, Birch R, Anand P, Buell GN.

Pain. 2005 Apr;114(3):386-96.

PMID:
15777864
16.

Interferon-gamma induces characteristics of central sensitization in spinal dorsal horn neurons in vitro.

Vikman KS, Hill RH, Backström E, Robertson B, Kristensson K.

Pain. 2003 Dec;106(3):241-51.

PMID:
14659507
17.

Interleukin-1beta enhances NMDA receptor-mediated intracellular calcium increase through activation of the Src family of kinases.

Viviani B, Bartesaghi S, Gardoni F, Vezzani A, Behrens MM, Bartfai T, Binaglia M, Corsini E, Di Luca M, Galli CL, Marinovich M.

J Neurosci. 2003 Sep 24;23(25):8692-700.

18.

Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain.

Coull JA, Boudreau D, Bachand K, Prescott SA, Nault F, Sík A, De Koninck P, De Koninck Y.

Nature. 2003 Aug 21;424(6951):938-42.

PMID:
12931188
19.

P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury.

Tsuda M, Shigemoto-Mogami Y, Koizumi S, Mizokoshi A, Kohsaka S, Salter MW, Inoue K.

Nature. 2003 Aug 14;424(6950):778-83.

20.

P2X3 receptors and peripheral pain mechanisms.

North RA.

J Physiol. 2004 Jan 15;554(Pt 2):301-8. Epub 2003 Jun 27. Review.

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