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Results: 1 to 20 of 109

1.

Inhibition of the Mr 70,000 S6 kinase pathway by rapamycin results in chromosome malsegregation in yeast and mammalian cells.

Bonatti S, Simili M, Galli A, Bagnato P, Pigullo S, Schiestl RH, Abbondandolo A.

Chromosoma. 1998 Dec;107(6-7):498-506.

PMID:
9914383
[PubMed - indexed for MEDLINE]
2.

Altered centrosomes in ataxia-telangiectasia cells and rapamycin-treated Chinese hamster cells.

Bonatti S, Simili M, Benedetti PA, Morandi F, Menichini P, Del Carratore R, Barale R, Abbondandolo A.

Environ Mol Mutagen. 2005 Oct;46(3):164-73.

PMID:
15920752
[PubMed - indexed for MEDLINE]
3.

p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes.

Brennan P, Babbage JW, Thomas G, Cantrell D.

Mol Cell Biol. 1999 Jul;19(7):4729-38.

PMID:
10373522
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase.

Kuo CJ, Chung J, Fiorentino DF, Flanagan WM, Blenis J, Crabtree GR.

Nature. 1992 Jul 2;358(6381):70-3.

PMID:
1614535
[PubMed - indexed for MEDLINE]
5.

Effects of rapamycin on cell proliferation and phosphorylation of mTOR and p70(S6K) in HepG2 and HepG2 cells overexpressing constitutively active Akt/PKB.

Varma S, Khandelwal RL.

Biochim Biophys Acta. 2007 Jan;1770(1):71-8. Epub 2006 Aug 1.

PMID:
16952420
[PubMed - indexed for MEDLINE]
Free Article
6.

TOR action in mammalian cells and in Caenorhabditis elegans.

Long X, Müller F, Avruch J.

Curr Top Microbiol Immunol. 2004;279:115-38. Review.

PMID:
14560955
[PubMed - indexed for MEDLINE]
7.

Induction of apoptosis and inhibition of signalling pathways by alkylated purines.

Bonatti S, Pigullo S, Simili M, Abbondandolo A.

Mutagenesis. 2000 Jul;15(4):361-6.

PMID:
10887217
[PubMed - indexed for MEDLINE]
Free Article
9.

Activation of the p70 S6 kinase and phosphorylation of the 4E-BP1 repressor of mRNA translation by type I interferons.

Lekmine F, Uddin S, Sassano A, Parmar S, Brachmann SM, Majchrzak B, Sonenberg N, Hay N, Fish EN, Platanias LC.

J Biol Chem. 2003 Jul 25;278(30):27772-80. Epub 2003 May 20.

PMID:
12759354
[PubMed - indexed for MEDLINE]
Free Article
10.

Acetaldehyde promotes rapamycin-dependent activation of p70(S6K) and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells.

Fang CX, Yang X, Sreejayan N, Ren J.

Exp Neurol. 2007 Jan;203(1):196-204. Epub 2006 Sep 7.

PMID:
16962100
[PubMed - indexed for MEDLINE]
11.

Rapamycin-resistant phosphorylation of the initiation factor-4E-binding protein (4E-BP1) in v-SRC-transformed hamster fibroblasts.

Tuhácková Z, Sovová V, Sloncová E, Proud CG.

Int J Cancer. 1999 Jun 11;81(6):963-9.

PMID:
10362146
[PubMed - indexed for MEDLINE]
12.

The rapamycin-sensitive signal transduction pathway as a target for cancer therapy.

Hidalgo M, Rowinsky EK.

Oncogene. 2000 Dec 27;19(56):6680-6. Review.

PMID:
11426655
[PubMed - indexed for MEDLINE]
Free Article
13.

Rapamycin-insensitive regulation of 4e-BP1 in regenerating rat liver.

Jiang YP, Ballou LM, Lin RZ.

J Biol Chem. 2001 Apr 6;276(14):10943-51. Epub 2001 Jan 25.

PMID:
11278364
[PubMed - indexed for MEDLINE]
Free Article
14.

Assessment of cell-signaling pathways in the regulation of mammalian target of rapamycin (mTOR) by amino acids in rat adipocytes.

Pham PT, Heydrick SJ, Fox HL, Kimball SR, Jefferson LS Jr, Lynch CJ.

J Cell Biochem. 2000 Sep 7;79(3):427-41.

PMID:
10972980
[PubMed - indexed for MEDLINE]
15.

Pharmacodynamic Evaluation of CCI-779, an Inhibitor of mTOR, in Cancer Patients.

Peralba JM, DeGraffenried L, Friedrichs W, Fulcher L, Grünwald V, Weiss G, Hidalgo M.

Clin Cancer Res. 2003 Aug 1;9(8):2887-92.

PMID:
12912932
[PubMed - indexed for MEDLINE]
Free Article
16.

Uncoupling p70(s6) kinase activation and proliferation: rapamycin-resistant proliferation of human CD8(+) T lymphocytes.

Slavik JM, Lim DG, Burakoff SJ, Hafler DA.

J Immunol. 2001 Mar 1;166(5):3201-9.

PMID:
11207273
[PubMed - indexed for MEDLINE]
Free Article
18.

Ionizing radiation enhances double-strand-break repair in rapamycin-treated ataxia telangiectasia lymphoblasts.

Sikpi MO, Wang Y.

Int J Radiat Biol. 2000 Feb;76(2):177-87.

PMID:
10716639
[PubMed - indexed for MEDLINE]
19.

L-Asparaginase inhibits the rapamycin-targeted signaling pathway.

Iiboshi Y, Papst PJ, Hunger SP, Terada N.

Biochem Biophys Res Commun. 1999 Jul 5;260(2):534-9.

PMID:
10403802
[PubMed - indexed for MEDLINE]
20.

Myogenic differentiation is dependent on both the kinase function and the N-terminal sequence of mammalian target of rapamycin.

Shu L, Zhang X, Houghton PJ.

J Biol Chem. 2002 May 10;277(19):16726-32. Epub 2002 Mar 1.

PMID:
11875068
[PubMed - indexed for MEDLINE]
Free Article

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