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Results: 1 to 20 of 95

1.

The mechanism of action of T7 DNA polymerase.

Doublié S, Ellenberger T.

Curr Opin Struct Biol. 1998 Dec;8(6):704-12. Review.

PMID:
9914251
[PubMed - indexed for MEDLINE]
2.

Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution.

Doublié S, Tabor S, Long AM, Richardson CC, Ellenberger T.

Nature. 1998 Jan 15;391(6664):251-8.

PMID:
9440688
[PubMed - indexed for MEDLINE]
3.

Evading the proofreading machinery of a replicative DNA polymerase: induction of a mutation by an environmental carcinogen.

Perlow RA, Broyde S.

J Mol Biol. 2001 Jun 1;309(2):519-36.

PMID:
11371169
[PubMed - indexed for MEDLINE]
4.

Conformational changes during normal and error-prone incorporation of nucleotides by a Y-family DNA polymerase detected by 2-aminopurine fluorescence.

DeLucia AM, Grindley ND, Joyce CM.

Biochemistry. 2007 Sep 25;46(38):10790-803. Epub 2007 Aug 29.

PMID:
17725324
[PubMed - indexed for MEDLINE]
5.

Mismatch-induced conformational distortions in polymerase beta support an induced-fit mechanism for fidelity.

Arora K, Beard WA, Wilson SH, Schlick T.

Biochemistry. 2005 Oct 11;44(40):13328-41.

PMID:
16201758
[PubMed - indexed for MEDLINE]
6.

Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7.

Li Y, Dutta S, Doublié S, Bdour HM, Taylor JS, Ellenberger T.

Nat Struct Mol Biol. 2004 Aug;11(8):784-90. Epub 2004 Jul 4.

PMID:
15235589
[PubMed - indexed for MEDLINE]
7.

Altering DNA polymerase incorporation fidelity by distorting the dNTP binding pocket with a bulky carcinogen-damaged template.

Yan SF, Wu M, Geacintov NE, Broyde S.

Biochemistry. 2004 Jun 22;43(24):7750-65.

PMID:
15196018
[PubMed - indexed for MEDLINE]
8.

Extending the understanding of mutagenicity: structural insights into primer-extension past a benzo[a]pyrene diol epoxide-DNA adduct.

Perlow RA, Broyde S.

J Mol Biol. 2003 Apr 4;327(4):797-818.

PMID:
12654264
[PubMed - indexed for MEDLINE]
9.

Toward understanding the mutagenicity of an environmental carcinogen: structural insights into nucleotide incorporation preferences.

Perlow RA, Broyde S.

J Mol Biol. 2002 Sep 13;322(2):291-309.

PMID:
12217692
[PubMed - indexed for MEDLINE]
10.

DNA-thumb interactions and processivity of T7 DNA polymerase in comparison to yeast polymerase eta.

Cannistraro VJ, Taylor JS.

J Biol Chem. 2004 Apr 30;279(18):18288-95. Epub 2004 Feb 10.

PMID:
14871898
[PubMed - indexed for MEDLINE]
Free Article
11.

Crystal structure of a pol alpha family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9 degrees N-7.

Rodriguez AC, Park HW, Mao C, Beese LS.

J Mol Biol. 2000 Jun 2;299(2):447-62.

PMID:
10860752
[PubMed - indexed for MEDLINE]
12.

Role of the C-terminal residue of the DNA polymerase of bacteriophage T7.

Kumar JK, Tabor S, Richardson CC.

J Biol Chem. 2001 Sep 14;276(37):34905-12. Epub 2001 Jul 13.

PMID:
11454860
[PubMed - indexed for MEDLINE]
Free Article
13.

Computer simulation of the chemical catalysis of DNA polymerases: discriminating between alternative nucleotide insertion mechanisms for T7 DNA polymerase.

Florián J, Goodman MF, Warshel A.

J Am Chem Soc. 2003 Jul 9;125(27):8163-77.

PMID:
12837086
[PubMed - indexed for MEDLINE]
14.

Polymerase-tailored variations in the water-mediated and substrate-assisted mechanism for nucleotidyl transfer: insights from a study of T7 DNA polymerase.

Wang L, Broyde S, Zhang Y.

J Mol Biol. 2009 Jun 19;389(4):787-96. doi: 10.1016/j.jmb.2009.04.029. Epub 2009 Apr 21.

PMID:
19389406
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Fluorescence of 2-aminopurine reveals rapid conformational changes in the RB69 DNA polymerase-primer/template complexes upon binding and incorporation of matched deoxynucleoside triphosphates.

Zhang H, Cao W, Zakharova E, Konigsberg W, De La Cruz EM.

Nucleic Acids Res. 2007;35(18):6052-62. Epub 2007 Aug 30.

PMID:
17766250
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Processivity of DNA polymerases: two mechanisms, one goal.

Kelman Z, Hurwitz J, O'Donnell M.

Structure. 1998 Feb 15;6(2):121-5. Review.

PMID:
9519403
[PubMed - indexed for MEDLINE]
17.

Functional hydrogen-bonding map of the minor groove binding tracks of six DNA polymerases.

Morales JC, Kool ET.

Biochemistry. 2000 Oct 24;39(42):12979-88.

PMID:
11041863
[PubMed - indexed for MEDLINE]
18.

Accuracy, lesion bypass, strand displacement and translocation by DNA polymerases.

Steitz TA, Yin YW.

Philos Trans R Soc Lond B Biol Sci. 2004 Jan 29;359(1441):17-23. Review.

PMID:
15065652
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Functional evidence for a small and rigid active site in a high fidelity DNA polymerase: probing T7 DNA polymerase with variably sized base pairs.

Kim TW, Brieba LG, Ellenberger T, Kool ET.

J Biol Chem. 2006 Jan 27;281(4):2289-95. Epub 2005 Nov 27.

PMID:
16311403
[PubMed - indexed for MEDLINE]
Free Article
20.

Structure of a transcribing T7 RNA polymerase initiation complex.

Cheetham GM, Steitz TA.

Science. 1999 Dec 17;286(5448):2305-9.

PMID:
10600732
[PubMed - indexed for MEDLINE]
Free Article

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