Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 239

1.

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway.

Wu X, Senechal K, Neshat MS, Whang YE, Sawyers CL.

Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15587-91.

PMID:
9861013
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway.

Ramaswamy S, Nakamura N, Vazquez F, Batt DB, Perera S, Roberts TM, Sellers WR.

Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2110-5.

PMID:
10051603
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN.

Pianetti S, Arsura M, Romieu-Mourez R, Coffey RJ, Sonenshein GE.

Oncogene. 2001 Mar 15;20(11):1287-99.

PMID:
11313873
[PubMed - indexed for MEDLINE]
Free Article
4.

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells.

Li DM, Sun H.

Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15406-11.

PMID:
9860981
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

PTEN tumour suppressor is linked to the cell cycle control through the retinoblastoma protein.

Paramio JM, Navarro M, Segrelles C, Gómez-Casero E, Jorcano JL.

Oncogene. 1999 Dec 9;18(52):7462-8.

PMID:
10602505
[PubMed - indexed for MEDLINE]
Free Article
6.

Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades.

Lu Y, Yu Q, Liu JH, Zhang J, Wang H, Koul D, McMurray JS, Fang X, Yung WK, Siminovitch KA, Mills GB.

J Biol Chem. 2003 Oct 10;278(41):40057-66. Epub 2003 Jul 17.

PMID:
12869565
[PubMed - indexed for MEDLINE]
Free Article
7.

Akt regulates COX-2 mRNA and protein expression in mutated-PTEN human endometrial cancer cells.

St-Germain ME, Gagnon V, Mathieu I, Parent S, Asselin E.

Int J Oncol. 2004 May;24(5):1311-24.

PMID:
15067356
[PubMed - indexed for MEDLINE]
8.

Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.

Haas-Kogan D, Shalev N, Wong M, Mills G, Yount G, Stokoe D.

Curr Biol. 1998 Oct 22;8(21):1195-8.

PMID:
9799739
[PubMed - indexed for MEDLINE]
Free Article
9.

Loss of PTEN expression leading to high Akt activation in human multiple myelomas.

Hyun T, Yam A, Pece S, Xie X, Zhang J, Miki T, Gutkind JS, Li W.

Blood. 2000 Nov 15;96(10):3560-8.

PMID:
11071655
[PubMed - indexed for MEDLINE]
Free Article
10.

PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells.

Choi Y, Zhang J, Murga C, Yu H, Koller E, Monia BP, Gutkind JS, Li W.

Oncogene. 2002 Aug 8;21(34):5289-300.

PMID:
12149650
[PubMed - indexed for MEDLINE]
Free Article
11.

Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells.

Persad S, Attwell S, Gray V, Delcommenne M, Troussard A, Sanghera J, Dedhar S.

Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3207-12.

PMID:
10716737
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

MMAC1/PTEN inhibits cell growth and induces chemosensitivity to doxorubicin in human bladder cancer cells.

Tanaka M, Koul D, Davies MA, Liebert M, Steck PA, Grossman HB.

Oncogene. 2000 Nov 9;19(47):5406-12.

PMID:
11103942
[PubMed - indexed for MEDLINE]
Free Article
13.

PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death.

Weng LP, Smith WM, Dahia PL, Ziebold U, Gil E, Lees JA, Eng C.

Cancer Res. 1999 Nov 15;59(22):5808-14.

PMID:
10582703
[PubMed - indexed for MEDLINE]
Free Article
14.

PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kappaB-dependent pathway.

Kim S, Domon-Dell C, Wang Q, Chung DH, Di Cristofano A, Pandolfi PP, Freund JN, Evers BM.

Gastroenterology. 2002 Oct;123(4):1163-78.

PMID:
12360479
[PubMed - indexed for MEDLINE]
15.

Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIK3CA amplification in gastric carcinoma.

Byun DS, Cho K, Ryu BK, Lee MG, Park JI, Chae KS, Kim HJ, Chi SG.

Int J Cancer. 2003 Apr 10;104(3):318-27.

PMID:
12569555
[PubMed - indexed for MEDLINE]
16.

Overexpression of PTEN/MMAC1 and decreased activation of Akt in human papillomavirus-infected laryngeal papillomas.

Zhang P, Steinberg BM.

Cancer Res. 2000 Mar 1;60(5):1457-62.

PMID:
10728713
[PubMed - indexed for MEDLINE]
Free Article
17.

Pharmacogenomic profiling of the PI3K/PTEN-AKT-mTOR pathway in common human tumors.

Xu G, Zhang W, Bertram P, Zheng XF, McLeod H.

Int J Oncol. 2004 Apr;24(4):893-900.

PMID:
15010827
[PubMed - indexed for MEDLINE]
18.

Indole-3-carbinol inhibits protein kinase B/Akt and induces apoptosis in the human breast tumor cell line MDA MB468 but not in the nontumorigenic HBL100 line.

Howells LM, Gallacher-Horley B, Houghton CE, Manson MM, Hudson EA.

Mol Cancer Ther. 2002 Nov;1(13):1161-72.

PMID:
12479697
[PubMed - indexed for MEDLINE]
Free Article
19.

Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functions.

Leslie NR, Bennett D, Gray A, Pass I, Hoang-Xuan K, Downes CP.

Biochem J. 2001 Jul 15;357(Pt 2):427-35.

PMID:
11439092
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways.

Gu J, Tamura M, Yamada KM.

J Cell Biol. 1998 Nov 30;143(5):1375-83.

PMID:
9832564
[PubMed - indexed for MEDLINE]
Free PMC Article
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk