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Results: 1 to 20 of 160

1.

Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis.

Davies MA, Lu Y, Sano T, Fang X, Tang P, LaPushin R, Koul D, Bookstein R, Stokoe D, Yung WK, Mills GB, Steck PA.

Cancer Res. 1998 Dec 1;58(23):5285-90. Erratum in: Cancer Res 1999 Mar 1;59(5):1167.

PMID:
9850049
[PubMed - indexed for MEDLINE]
Free Article
2.
3.

Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.

Haas-Kogan D, Shalev N, Wong M, Mills G, Yount G, Stokoe D.

Curr Biol. 1998 Oct 22;8(21):1195-8.

PMID:
9799739
[PubMed - indexed for MEDLINE]
Free Article
4.

MMAC1/PTEN inhibits cell growth and induces chemosensitivity to doxorubicin in human bladder cancer cells.

Tanaka M, Koul D, Davies MA, Liebert M, Steck PA, Grossman HB.

Oncogene. 2000 Nov 9;19(47):5406-12.

PMID:
11103942
[PubMed - indexed for MEDLINE]
Free Article
5.

Adenoviral-mediated expression of MMAC/PTEN inhibits proliferation and metastasis of human prostate cancer cells.

Davies MA, Kim SJ, Parikh NU, Dong Z, Bucana CD, Gallick GE.

Clin Cancer Res. 2002 Jun;8(6):1904-14.

PMID:
12060635
[PubMed - indexed for MEDLINE]
Free Article
6.

Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways.

Gu J, Tamura M, Yamada KM.

J Cell Biol. 1998 Nov 30;143(5):1375-83.

PMID:
9832564
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

MDA-7 regulates cell growth and radiosensitivity in vitro of primary (non-established) human glioma cells.

Yacoub A, Mitchell C, Hong Y, Gopalkrishnan RV, Su ZZ, Gupta P, Sauane M, Lebedeva IV, Curiel DT, Mahasreshti PJ, Rosenfeld MR, Broaddus WC, James CD, Grant S, Fisher PB, Dent P.

Cancer Biol Ther. 2004 Aug;3(8):739-51. Epub 2004 Aug 10.

PMID:
15197348
[PubMed - indexed for MEDLINE]
Free Article
8.

PTEN gene therapy induces growth inhibition and increases efficacy of chemotherapy in prostate cancer.

Tanaka M, Rosser CJ, Grossman HB.

Cancer Detect Prev. 2005;29(2):170-4. Epub 2004 Dec 10.

PMID:
15829377
[PubMed - indexed for MEDLINE]
9.

Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth.

Edwards LA, Thiessen B, Dragowska WH, Daynard T, Bally MB, Dedhar S.

Oncogene. 2005 May 19;24(22):3596-605.

PMID:
15782140
[PubMed - indexed for MEDLINE]
10.

Inhibition of vascular smooth muscle cell proliferation, migration, and survival by the tumor suppressor protein PTEN.

Huang J, Kontos CD.

Arterioscler Thromb Vasc Biol. 2002 May 1;22(5):745-51.

PMID:
12006385
[PubMed - indexed for MEDLINE]
Free Article
11.

PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells.

Choi Y, Zhang J, Murga C, Yu H, Koller E, Monia BP, Gutkind JS, Li W.

Oncogene. 2002 Aug 8;21(34):5289-300.

PMID:
12149650
[PubMed - indexed for MEDLINE]
Free Article
12.

PTEN gene transfer in human malignant glioma: sensitization to irradiation and CD95L-induced apoptosis.

Wick W, Furnari FB, Naumann U, Cavenee WK, Weller M.

Oncogene. 1999 Jul 8;18(27):3936-43.

PMID:
10435616
[PubMed - indexed for MEDLINE]
Free Article
13.

Adenoviral-mediated expression of a kinase-dead mutant of Akt induces apoptosis selectively in tumor cells and suppresses tumor growth in mice.

Jetzt A, Howe JA, Horn MT, Maxwell E, Yin Z, Johnson D, Kumar CC.

Cancer Res. 2003 Oct 15;63(20):6697-706.

PMID:
14583464
[PubMed - indexed for MEDLINE]
Free Article
14.

Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN.

Davies MA, Koul D, Dhesi H, Berman R, McDonnell TJ, McConkey D, Yung WK, Steck PA.

Cancer Res. 1999 Jun 1;59(11):2551-6.

PMID:
10363971
[PubMed - indexed for MEDLINE]
Free Article
15.

Adenovirus-mediated transfer of the PTEN gene inhibits human colorectal cancer growth in vitro and in vivo.

Saito Y, Swanson X, Mhashilkar AM, Oida Y, Schrock R, Branch CD, Chada S, Zumstein L, Ramesh R.

Gene Ther. 2003 Nov;10(23):1961-9.

PMID:
14528320
[PubMed - indexed for MEDLINE]
16.

The tumor suppressor PTEN regulates T cell survival and antigen receptor signaling by acting as a phosphatidylinositol 3-phosphatase.

Wang X, Gjörloff-Wingren A, Saxena M, Pathan N, Reed JC, Mustelin T.

J Immunol. 2000 Feb 15;164(4):1934-9.

PMID:
10657643
[PubMed - indexed for MEDLINE]
Free Article
17.

Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN.

Koul D, Parthasarathy R, Shen R, Davies MA, Jasser SA, Chintala SK, Rao JS, Sun Y, Benvenisite EN, Liu TJ, Yung WK.

Oncogene. 2001 Oct 11;20(46):6669-78.

PMID:
11709701
[PubMed - indexed for MEDLINE]
Free Article
18.

Role of PTEN and Akt in the regulation of growth and apoptosis in human osteoblastic cells.

Nielsen-Preiss SM, Silva SR, Gillette JM.

J Cell Biochem. 2003 Dec 1;90(5):964-75.

PMID:
14624456
[PubMed - indexed for MEDLINE]
19.

Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells.

Persad S, Attwell S, Gray V, Delcommenne M, Troussard A, Sanghera J, Dedhar S.

Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3207-12.

PMID:
10716737
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades.

Lu Y, Yu Q, Liu JH, Zhang J, Wang H, Koul D, McMurray JS, Fang X, Yung WK, Siminovitch KA, Mills GB.

J Biol Chem. 2003 Oct 10;278(41):40057-66. Epub 2003 Jul 17.

PMID:
12869565
[PubMed - indexed for MEDLINE]
Free Article
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