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Differential regulation of baboon SP-A1 and SP-A2 genes: structural and functional analysis of 5'-flanking DNA.

Li J, Gao E, Seidner SR, Mendelson CR.

Am J Physiol. 1998 Dec;275(6 Pt 1):L1078-88.


14-3-3 isoforms bind directly Exon B of the 5'UTR of human surfactant Protein A2 mRNA.

Noutsios GT, Ghattas P, Bennett S, Floros J.

Am J Physiol Lung Cell Mol Physiol. 2015 May 22:ajplung.00088.2015. doi: 10.1152/ajplung.00088.2015. [Epub ahead of print]


The potential molecular basis of bursal-derived BSP-II on immune induction and antitumor.

Zhou GF, Liu QT, Zhou B, Qiu YF, Liu XD, Ma ZY, Feng XL, Cao RB, Chen PY.

J Vet Sci. 2015 Jan 30. [Epub ahead of print]


Regulation of translation by upstream translation initiation codons of surfactant protein A1 splice variants.

Tsotakos N, Silveyra P, Lin Z, Thomas N, Vaid M, Floros J.

Am J Physiol Lung Cell Mol Physiol. 2015 Jan 1;308(1):L58-75. doi: 10.1152/ajplung.00058.2014. Epub 2014 Oct 17.


Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome.

Phelps DS, Umstead TM, Floros J.

J Proteomics. 2014 Aug 28;108:427-44. doi: 10.1016/j.jprot.2014.06.007. Epub 2014 Jun 18.


Differences in the alveolar macrophage proteome in transgenic mice expressing human SP-A1 and SP-A2.

Phelps DS, Umstead TM, Silveyra P, Hu S, Wang G, Floros J.

J Proteom Genom Res. 2013 Apr 1;1(2):2-26.


Leptin promotes fetal lung maturity and upregulates SP-A expression in pulmonary alveoli type-II epithelial cells involving TTF-1 activation.

Chen H, Zhang JP, Huang H, Wang ZH, Cheng R, Cai WB.

PLoS One. 2013 Jul 22;8(7):e69297. doi: 10.1371/journal.pone.0069297. Print 2013.


ErbB4 is an upstream regulator of TTF-1 fetal mouse lung type II cell development in vitro.

Zscheppang K, Giese U, Hoenzke S, Wiegel D, Dammann CE.

Biochim Biophys Acta. 2013 Dec;1833(12):2690-702. doi: 10.1016/j.bbamcr.2013.06.030. Epub 2013 Jul 8.


Exon B of human surfactant protein A2 mRNA, alone or within its surrounding sequences, interacts with 14-3-3; role of cis-elements and secondary structure.

Noutsios GT, Silveyra P, Bhatti F, Floros J.

Am J Physiol Lung Cell Mol Physiol. 2013 Jun 1;304(11):L722-35. doi: 10.1152/ajplung.00324.2012. Epub 2013 Mar 22.


Lipopolysaccharide-induced expression of surfactant proteins A1 and A2 in human renal tubular epithelial cells.

Liu J, Hu F, Wang G, Zhou Q, Ding G.

J Inflamm (Lond). 2013 Jan 12;10(1):2. doi: 10.1186/1476-9255-10-2.


Genetic complexity of the human surfactant-associated proteins SP-A1 and SP-A2.

Silveyra P, Floros J.

Gene. 2013 Dec 1;531(2):126-32. doi: 10.1016/j.gene.2012.09.111. Epub 2012 Oct 12. Review.


[Differential gene expressions of polygonal cells and cuboidal cells in so-called pulmonary sclerosing hemangioma].

Wang Y, Dai S, Wang E.

Zhongguo Fei Ai Za Zhi. 2007 Dec 20;10(6):466-70. doi: 10.3779/j.issn.1009-3419.2007.06.04. Chinese.


The SP-C promoter facilitates alveolar type II epithelial cell-specific plasmid nuclear import and gene expression.

Degiulio JV, Kaufman CD, Dean DA.

Gene Ther. 2010 Apr;17(4):541-9. doi: 10.1038/gt.2009.166. Epub 2010 Jan 7.


Humanized SFTPA1 and SFTPA2 transgenic mice reveal functional divergence of SP-A1 and SP-A2: formation of tubular myelin in vivo requires both gene products.

Wang G, Guo X, Diangelo S, Thomas NJ, Floros J.

J Biol Chem. 2010 Apr 16;285(16):11998-2010. doi: 10.1074/jbc.M109.046243. Epub 2010 Jan 4.


NKX2-1 mutations leading to surfactant protein promoter dysregulation cause interstitial lung disease in "Brain-Lung-Thyroid Syndrome".

Guillot L, Carré A, Szinnai G, Castanet M, Tron E, Jaubert F, Broutin I, Counil F, Feldmann D, Clement A, Polak M, Epaud R.

Hum Mutat. 2010 Feb;31(2):E1146-62. doi: 10.1002/humu.21183.


Carcinoembryonic cell adhesion molecule 6 in human lung: regulated expression of a multifunctional type II cell protein.

Kolla V, Gonzales LW, Bailey NA, Wang P, Angampalli S, Godinez MH, Madesh M, Ballard PL.

Am J Physiol Lung Cell Mol Physiol. 2009 Jun;296(6):L1019-30. doi: 10.1152/ajplung.90596.2008. Epub 2009 Mar 27.


Regulation of surfactant protein B gene expression in bone marrow-derived cells.

Field-Corbett C, English K, O'Dea S.

Stem Cells. 2009 Mar;27(3):662-9. doi: 10.1634/stemcells.2008-0313.


Thyroid transcription factor-1 (TTF-1/Nkx2.1/TITF1) gene regulation in the lung.

Boggaram V.

Clin Sci (Lond). 2009 Jan;116(1):27-35. doi: 10.1042/CS20080068. Review.

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