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Items: 1 to 20 of 316

1.

TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis.

Oft M, Heider KH, Beug H.

Curr Biol. 1998 Nov 19;8(23):1243-52.

2.

Transforming growth factor-β suppresses metastasis in a subset of human colon carcinoma cells.

Simms NA, Rajput A, Sharratt EA, Ongchin M, Teggart CA, Wang J, Brattain MG.

BMC Cancer. 2012 Jun 6;12:221. doi: 10.1186/1471-2407-12-221.

3.

Restoring TGFbeta function in microsatellite unstable (MSI-H) colorectal cancer reduces tumourigenicity but increases metastasis formation.

Warusavitarne J, McDougall F, de Silva K, Barnetson R, Messina M, Robinson BG, Schnitzler M.

Int J Colorectal Dis. 2009 Feb;24(2):139-44. doi: 10.1007/s00384-008-0606-x. Epub 2008 Nov 5.

PMID:
18985362
4.

Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer.

Pardali K, Moustakas A.

Biochim Biophys Acta. 2007 Jan;1775(1):21-62. Epub 2006 Jul 8. Review.

PMID:
16904831
5.

Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro.

Brown KA, Aakre ME, Gorska AE, Price JO, Eltom SE, Pietenpol JA, Moses HL.

Breast Cancer Res. 2004;6(3):R215-31. Epub 2004 Mar 17.

6.

Growth inhibitory signalling by TGFbeta is blocked in Ras-transformed intestinal epithelial cells at a post-receptor locus.

Jiang B, Zhang JS, Du J, Urrutia R, Barnard J.

Cell Signal. 2003 Jul;15(7):699-708.

PMID:
12742230
7.

ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells.

Waerner T, Alacakaptan M, Tamir I, Oberauer R, Gal A, Brabletz T, Schreiber M, Jechlinger M, Beug H.

Cancer Cell. 2006 Sep;10(3):227-39.

8.

p38 mitogen-activated protein kinase is required for TGFbeta-mediated fibroblastic transdifferentiation and cell migration.

Bakin AV, Rinehart C, Tomlinson AK, Arteaga CL.

J Cell Sci. 2002 Aug 1;115(Pt 15):3193-206.

9.

Prostate cancer cells regulate growth and differentiation of bone marrow endothelial cells through TGFbeta and its receptor, TGFbetaRII.

Barrett JM, Rovedo MA, Tajuddin AM, Jilling T, Macoska JA, MacDonald J, Mangold KA, Kaul KL.

Prostate. 2006 May 1;66(6):632-50.

PMID:
16388503
10.

Inhibition of transforming growth factor beta signaling reduces pancreatic adenocarcinoma growth and invasiveness.

Gaspar NJ, Li L, Kapoun AM, Medicherla S, Reddy M, Li G, O'Young G, Quon D, Henson M, Damm DL, Muiru GT, Murphy A, Higgins LS, Chakravarty S, Wong DH.

Mol Pharmacol. 2007 Jul;72(1):152-61. Epub 2007 Mar 30.

11.

Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways.

Janda E, Lehmann K, Killisch I, Jechlinger M, Herzig M, Downward J, Beug H, Grünert S.

J Cell Biol. 2002 Jan 21;156(2):299-313. Epub 2002 Jan 14.

12.

NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression.

Huber MA, Azoitei N, Baumann B, Grünert S, Sommer A, Pehamberger H, Kraut N, Beug H, Wirth T.

J Clin Invest. 2004 Aug;114(4):569-81.

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14.

A novel dominant negative Smad2 mutation in a TGFbeta resistant human carcinoma cell line.

Tsang KJ, Tsang D, Brown TN, Crowe DL.

Anticancer Res. 2002 Jan-Feb;22(1A):13-9.

PMID:
12017275
15.

beta-Catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition.

Eger A, Stockinger A, Park J, Langkopf E, Mikula M, Gotzmann J, Mikulits W, Beug H, Foisner R.

Oncogene. 2004 Apr 8;23(15):2672-2680.

PMID:
14755243
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18.

Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis.

Gal A, Sjöblom T, Fedorova L, Imreh S, Beug H, Moustakas A.

Oncogene. 2008 Feb 21;27(9):1218-30. Epub 2007 Aug 27.

PMID:
17724470
19.

Inhibition of PI3 kinase/Akt pathway is required for BMP2-induced EMT and invasion.

Kang MH, Kang HN, Kim JL, Kim JS, Oh SC, Yoo YA.

Oncol Rep. 2009 Sep;22(3):525-34.

PMID:
19639199
20.

Ionizing radiation predisposes nonmalignant human mammary epithelial cells to undergo transforming growth factor beta induced epithelial to mesenchymal transition.

Andarawewa KL, Erickson AC, Chou WS, Costes SV, Gascard P, Mott JD, Bissell MJ, Barcellos-Hoff MH.

Cancer Res. 2007 Sep 15;67(18):8662-70.

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