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Results: 1 to 20 of 177

1.

Inhibition of the epithelial Na+ channel by interaction of Nedd4 with a PY motif deleted in Liddle's syndrome.

Goulet CC, Volk KA, Adams CM, Prince LS, Stokes JB, Snyder PM.

J Biol Chem. 1998 Nov 6;273(45):30012-7.

PMID:
9792722
[PubMed - indexed for MEDLINE]
Free Article
2.

Multiple WW domains, but not the C2 domain, are required for inhibition of the epithelial Na+ channel by human Nedd4.

Snyder PM, Olson DR, McDonald FJ, Bucher DB.

J Biol Chem. 2001 Jul 27;276(30):28321-6. Epub 2001 May 18.

PMID:
11359767
[PubMed - indexed for MEDLINE]
Free Article
3.

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome.

Staub O, Dho S, Henry P, Correa J, Ishikawa T, McGlade J, Rotin D.

EMBO J. 1996 May 15;15(10):2371-80.

PMID:
8665844
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination.

Staub O, Abriel H, Plant P, Ishikawa T, Kanelis V, Saleki R, Horisberger JD, Schild L, Rotin D.

Kidney Int. 2000 Mar;57(3):809-15. Review.

PMID:
10720933
[PubMed - indexed for MEDLINE]
Free Article
5.

Liddle's syndrome: a novel mouse Nedd4 isoform regulates the activity of the epithelial Na(+) channel.

Kamynina E, Debonneville C, Hirt RP, Staub O.

Kidney Int. 2001 Aug;60(2):466-71. Review.

PMID:
11473628
[PubMed - indexed for MEDLINE]
Free Article
6.

Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome.

Abriel H, Loffing J, Rebhun JF, Pratt JH, Schild L, Horisberger JD, Rotin D, Staub O.

J Clin Invest. 1999 Mar;103(5):667-73.

PMID:
10074483
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Regulation of the epithelial sodium channel by N4WBP5A, a novel Nedd4/Nedd4-2-interacting protein.

Konstas AA, Shearwin-Whyatt LM, Fotia AB, Degger B, Riccardi D, Cook DI, Korbmacher C, Kumar S.

J Biol Chem. 2002 Aug 16;277(33):29406-16. Epub 2002 Jun 5.

PMID:
12050153
[PubMed - indexed for MEDLINE]
Free Article
8.

Cystic fibrosis transmembrane conductance regulator inhibits epithelial Na+ channels carrying Liddle's syndrome mutations.

Hopf A, Schreiber R, Mall M, Greger R, Kunzelmann K.

J Biol Chem. 1999 May 14;274(20):13894-9.

PMID:
10318798
[PubMed - indexed for MEDLINE]
Free Article
9.

A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel.

Kamynina E, Debonneville C, Bens M, Vandewalle A, Staub O.

FASEB J. 2001 Jan;15(1):204-214.

PMID:
11149908
[PubMed - indexed for MEDLINE]
Free Article
10.

Ubiquitin-protein ligase WWP2 binds to and downregulates the epithelial Na(+) channel.

McDonald FJ, Western AH, McNeil JD, Thomas BC, Olson DR, Snyder PM.

Am J Physiol Renal Physiol. 2002 Sep;283(3):F431-6.

PMID:
12167593
[PubMed - indexed for MEDLINE]
Free Article
11.

A single WW domain is the predominant mediator of the interaction between the human ubiquitin-protein ligase Nedd4 and the human epithelial sodium channel.

Lott JS, Coddington-Lawson SJ, Teesdale-Spittle PH, McDonald FJ.

Biochem J. 2002 Feb 1;361(Pt 3):481-8.

PMID:
11802777
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Liddle's syndrome mutations increase Na+ transport through dual effects on epithelial Na+ channel surface expression and proteolytic cleavage.

Knight KK, Olson DR, Zhou R, Snyder PM.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2805-8. Epub 2006 Feb 13.

PMID:
16477034
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

All three WW domains of murine Nedd4 are involved in the regulation of epithelial sodium channels by intracellular Na+.

Harvey KF, Dinudom A, Komwatana P, Jolliffe CN, Day ML, Parasivam G, Cook DI, Kumar S.

J Biol Chem. 1999 Apr 30;274(18):12525-30.

PMID:
10212229
[PubMed - indexed for MEDLINE]
Free Article
14.

The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel.

Harvey KF, Dinudom A, Cook DI, Kumar S.

J Biol Chem. 2001 Mar 16;276(11):8597-601. Epub 2001 Jan 17.

PMID:
11244092
[PubMed - indexed for MEDLINE]
Free Article
15.

Affinity and specificity of interactions between Nedd4 isoforms and the epithelial Na+ channel.

Henry PC, Kanelis V, O'Brien MC, Kim B, Gautschi I, Forman-Kay J, Schild L, Rotin D.

J Biol Chem. 2003 May 30;278(22):20019-28. Epub 2003 Mar 22.

PMID:
12654927
[PubMed - indexed for MEDLINE]
Free Article
16.

Immunolocalization of the ubiquitin-protein ligase Nedd4 in tissues expressing the epithelial Na+ channel (ENaC).

Staub O, Yeger H, Plant PJ, Kim H, Ernst SA, Rotin D.

Am J Physiol. 1997 Jun;272(6 Pt 1):C1871-80.

PMID:
9227416
[PubMed - indexed for MEDLINE]
17.

Solution structure of a Nedd4 WW domain-ENaC peptide complex.

Kanelis V, Rotin D, Forman-Kay JD.

Nat Struct Biol. 2001 May;8(5):407-12.

PMID:
11323714
[PubMed - indexed for MEDLINE]
18.

The PY motif of ENaC, mutated in Liddle syndrome, regulates channel internalization, sorting and mobilization from subapical pool.

Lu C, Pribanic S, Debonneville A, Jiang C, Rotin D.

Traffic. 2007 Sep;8(9):1246-64. Epub 2007 Jul 1.

PMID:
17605762
[PubMed - indexed for MEDLINE]
19.

Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination.

Staub O, Gautschi I, Ishikawa T, Breitschopf K, Ciechanover A, Schild L, Rotin D.

EMBO J. 1997 Nov 3;16(21):6325-36.

PMID:
9351815
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Nedd4 mediates control of an epithelial Na+ channel in salivary duct cells by cytosolic Na+.

Dinudom A, Harvey KF, Komwatana P, Young JA, Kumar S, Cook DI.

Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):7169-73.

PMID:
9618557
[PubMed - indexed for MEDLINE]
Free PMC Article

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