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Results: 1 to 20 of 167

1.

Crystallization and preliminary X-ray diffraction studies of E. coli porphobilinogen synthase and its heavy-atom derivatives.

Shimoni-Livny L, Carrell HL, Wagner T, Kaufman Katz A, Afshar C, Mitchell LW, Volin M, Jaffe EK, Glusker JP.

Acta Crystallogr D Biol Crystallogr. 1998 May 1;54(Pt 3):438-40.

PMID:
9761921
[PubMed - indexed for MEDLINE]
2.

Mechanistic implications of mutations to the active site lysine of porphobilinogen synthase.

Mitchell LW, Volin M, Martins J, Jaffe EK.

J Biol Chem. 2001 Jan 12;276(2):1538-44.

PMID:
11032841
[PubMed - indexed for MEDLINE]
Free Article
3.

The phylogenetically conserved histidines of Escherichia coli porphobilinogen synthase are not required for catalysis.

Mitchell LW, Volin M, Jaffe EK.

J Biol Chem. 1995 Oct 13;270(41):24054-9.

PMID:
7592604
[PubMed - indexed for MEDLINE]
Free Article
4.

Mechanistic basis for suicide inactivation of porphobilinogen synthase by 4,7-dioxosebacic acid, an inhibitor that shows dramatic species selectivity.

Kervinen J, Jaffe EK, Stauffer F, Neier R, Wlodawer A, Zdanov A.

Biochemistry. 2001 Jul 27;40(28):8227-36.

PMID:
11444968
[PubMed - indexed for MEDLINE]
5.

Production, purification, and characterization of a Mg2+-responsive porphobilinogen synthase from Pseudomonas aeruginosa.

Frankenberg N, Heinz DW, Jahn D.

Biochemistry. 1999 Oct 19;38(42):13968-75.

PMID:
10529243
[PubMed - indexed for MEDLINE]
6.

Crystallization of 5-aminolaevulinic acid dehydratase from Escherichia coli and Saccharomyces cerevisiae and preliminary X-ray characterization of the crystals.

Erskine PT, Senior N, Maignan S, Cooper J, Lambert R, Lewis G, Spencer P, Awan S, Warren M, Tickle IJ, Thomas P, Wood SP, Shoolingin-Jordan PM.

Protein Sci. 1997 Aug;6(8):1774-6.

PMID:
9260292
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

High resolution crystal structure of a Mg2+-dependent porphobilinogen synthase.

Frankenberg N, Erskine PT, Cooper JB, Shoolingin-Jordan PM, Jahn D, Heinz DW.

J Mol Biol. 1999 Jun 11;289(3):591-602.

PMID:
10356331
[PubMed - indexed for MEDLINE]
8.

The porphobilinogen synthase catalyzed reaction mechanism.

Jaffe EK.

Bioorg Chem. 2004 Oct;32(5):316-25. Review.

PMID:
15381398
[PubMed - indexed for MEDLINE]
9.

5-Chloro[1,4-13C]levulinic acid modification of mammalian and bacterial porphobilinogen synthase suggests an active site containing two Zn(II).

Jaffe EK, Volin M, Myers CB, Abrams WR.

Biochemistry. 1994 Sep 27;33(38):11554-62.

PMID:
7918369
[PubMed - indexed for MEDLINE]
10.

Crystallization and preliminary X-ray diffraction studies of 5-chlorolevulinate-modified bovine porphobilinogen synthase and the Pb(II)-complexed enzyme.

Carrell HL, Glusker JP, Shimoni L, Keefe LJ, Afshar C, Volin M, Jaffe EK.

Acta Crystallogr D Biol Crystallogr. 1996 Mar 1;52(Pt 2):419-21.

PMID:
15299718
[PubMed]
11.

Porphobilinogen synthase from Escherichia coli is a Zn(II) metalloenzyme stimulated by Mg(II).

Mitchell LW, Jaffe EK.

Arch Biochem Biophys. 1993 Jan;300(1):169-77.

PMID:
8424649
[PubMed - indexed for MEDLINE]
12.

Species-specific inhibition of porphobilinogen synthase by 4-oxosebacic acid.

Jaffe EK, Kervinen J, Martins J, Stauffer F, Neier R, Wlodawer A, Zdanov A.

J Biol Chem. 2002 May 31;277(22):19792-9. Epub 2002 Mar 21.

PMID:
11909869
[PubMed - indexed for MEDLINE]
Free Article
13.

Crystallization and preliminary X-ray investigation of Escherichia coli porphobilinogen deaminase.

Jordan PM, Warren MJ, Mgbeje BI, Wood SP, Cooper JB, Louie G, Brownlie P, Lambert R, Blundell TL.

J Mol Biol. 1992 Mar 5;224(1):269-71.

PMID:
1548705
[PubMed - indexed for MEDLINE]
14.

5-Chlorolevulinate modification of porphobilinogen synthase identifies a potential role for the catalytic zinc.

Jaffe EK, Abrams WR, Kaempfen HX, Harris KA Jr.

Biochemistry. 1992 Feb 25;31(7):2113-23.

PMID:
1346974
[PubMed - indexed for MEDLINE]
15.

Crystallization and preliminary X-ray studies of glutathione synthetase from Escherichia coli B.

Kato H, Yamaguchi H, Hata Y, Nishioka T, Katsube Y, Oda J.

J Mol Biol. 1989 Oct 5;209(3):503-4.

PMID:
2685323
[PubMed - indexed for MEDLINE]
16.

Crystallization and preliminary X-ray diffraction studies of the cobalamin-binding domain of methionine synthase from Escherichia coli.

Luschinsky CL, Drummond JT, Matthews RG, Ludwig ML.

J Mol Biol. 1992 May 20;225(2):557-60.

PMID:
1593636
[PubMed - indexed for MEDLINE]
17.

X-ray structure of 5-aminolevulinic acid dehydratase from Escherichia coli complexed with the inhibitor levulinic acid at 2.0 A resolution.

Erskine PT, Norton E, Cooper JB, Lambert R, Coker A, Lewis G, Spencer P, Sarwar M, Wood SP, Warren MJ, Shoolingin-Jordan PM.

Biochemistry. 1999 Apr 6;38(14):4266-76.

PMID:
10194344
[PubMed - indexed for MEDLINE]
18.

Magnetic resonance studies on the active site and metal centers of Bradyrhizobium japonicum porphobilinogen synthase.

Petrovich RM, Jaffe EK.

Biochemistry. 1997 Oct 28;36(43):13421-7.

PMID:
9341235
[PubMed - indexed for MEDLINE]
19.

Characterization of the role of the stimulatory magnesium of Escherichia coli porphobilinogen synthase.

Jaffe EK, Ali S, Mitchell LW, Taylor KM, Volin M, Markham GD.

Biochemistry. 1995 Jan 10;34(1):244-51.

PMID:
7819203
[PubMed - indexed for MEDLINE]
20.

Porphobilinogen synthase from pea: expression from an artificial gene, kinetic characterization, and novel implications for subunit interactions.

Kervinen J, Dunbrack RL Jr, Litwin S, Martins J, Scarrow RC, Volin M, Yeung AT, Yoon E, Jaffe EK.

Biochemistry. 2000 Aug 1;39(30):9018-29.

PMID:
10913315
[PubMed - indexed for MEDLINE]
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