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Items: 1 to 20 of 91


Stimulation of p53-mediated transcriptional activation by the p53-binding proteins, 53BP1 and 53BP2.

Iwabuchi K, Li B, Massa HF, Trask BJ, Date T, Fields S.

J Biol Chem. 1998 Oct 2;273(40):26061-8.


Two cellular proteins that bind to wild-type but not mutant p53.

Iwabuchi K, Bartel PL, Li B, Marraccino R, Fields S.

Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):6098-102.


The 8-kDa dynein light chain binds to p53-binding protein 1 and mediates DNA damage-induced p53 nuclear accumulation.

Lo KW, Kan HM, Chan LN, Xu WG, Wang KP, Wu Z, Sheng M, Zhang M.

J Biol Chem. 2005 Mar 4;280(9):8172-9. Epub 2004 Dec 20.


Comparison of BRCT domains of BRCA1 and 53BP1: a biophysical analysis.

Ekblad CM, Friedler A, Veprintsev D, Weinberg RL, Itzhaki LS.

Protein Sci. 2004 Mar;13(3):617-25.


Hepatitis C virus core protein interacts with p53-binding protein, 53BP2/Bbp/ASPP2, and inhibits p53-mediated apoptosis.

Cao Y, Hamada T, Matsui T, Date T, Iwabuchi K.

Biochem Biophys Res Commun. 2004 Mar 19;315(4):788-95.


Binding of Rad51 and other peptide sequences to a promiscuous, highly electrostatic binding site in p53.

Friedler A, Veprintsev DB, Rutherford T, von Glos KI, Fersht AR.

J Biol Chem. 2005 Mar 4;280(9):8051-9. Epub 2004 Dec 20.


Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2.

Gorina S, Pavletich NP.

Science. 1996 Nov 8;274(5289):1001-5.


ASPP proteins specifically stimulate the apoptotic function of p53.

Samuels-Lev Y, O'Connor DJ, Bergamaschi D, Trigiante G, Hsieh JK, Zhong S, Campargue I, Naumovski L, Crook T, Lu X.

Mol Cell. 2001 Oct;8(4):781-94.


iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.

Bergamaschi D, Samuels Y, O'Neil NJ, Trigiante G, Crook T, Hsieh JK, O'Connor DJ, Zhong S, Campargue I, Tomlinson ML, Kuwabara PE, Lu X.

Nat Genet. 2003 Feb;33(2):162-7. Epub 2003 Jan 13.


ING1 represses transcription by direct DNA binding and through effects on p53.

Kataoka H, Bonnefin P, Vieyra D, Feng X, Hara Y, Miura Y, Joh T, Nakabayashi H, Vaziri H, Harris CC, Riabowol K.

Cancer Res. 2003 Sep 15;63(18):5785-92.


Potential role for 53BP1 in DNA end-joining repair through direct interaction with DNA.

Iwabuchi K, Basu BP, Kysela B, Kurihara T, Shibata M, Guan D, Cao Y, Hamada T, Imamura K, Jeggo PA, Date T, Doherty AJ.

J Biol Chem. 2003 Sep 19;278(38):36487-95. Epub 2003 Jun 24.


Regulation of the p53 homolog p73 by adenoviral oncogene E1A.

Das S, El-Deiry WS, Somasundaram K.

J Biol Chem. 2003 May 16;278(20):18313-20. Epub 2003 Mar 13.


Identification and characterization of HIPK2 interacting with p73 and modulating functions of the p53 family in vivo.

Kim EJ, Park JS, Um SJ.

J Biol Chem. 2002 Aug 30;277(35):32020-8. Epub 2002 Mar 29.


Functional interaction between p53 and the interferon-inducible nucleoprotein IFI 16.

Johnstone RW, Wei W, Greenway A, Trapani JA.

Oncogene. 2000 Dec 7;19(52):6033-42.


p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53.

Davison TS, Vagner C, Kaghad M, Ayed A, Caput D, Arrowsmith CH.

J Biol Chem. 1999 Jun 25;274(26):18709-14.


Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations.

Suad O, Rozenberg H, Brosh R, Diskin-Posner Y, Kessler N, Shimon LJ, Frolow F, Liran A, Rotter V, Shakked Z.

J Mol Biol. 2009 Jan 9;385(1):249-65. doi: 10.1016/j.jmb.2008.10.063. Epub 2008 Oct 30.

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