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Similar articles for PubMed (Select 9659915)


PAK kinases are directly coupled to the PIX family of nucleotide exchange factors.

Manser E, Loo TH, Koh CG, Zhao ZS, Chen XQ, Tan L, Tan I, Leung T, Lim L.

Mol Cell. 1998 Jan;1(2):183-92.


Structural analysis of the SH3 domain of beta-PIX and its interaction with alpha-p21 activated kinase (PAK).

Mott HR, Nietlispach D, Evetts KA, Owen D.

Biochemistry. 2005 Aug 23;44(33):10977-83.


Regulation of the Cool/Pix proteins: key binding partners of the Cdc42/Rac targets, the p21-activated kinases.

Feng Q, Albeck JG, Cerione RA, Yang W.

J Biol Chem. 2002 Feb 15;277(7):5644-50. Epub 2001 Dec 10.


Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix.

ten Klooster JP, Jaffer ZM, Chernoff J, Hordijk PL.

J Cell Biol. 2006 Feb 27;172(5):759-69. Epub 2006 Feb 21.


The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42.

Park E, Na M, Choi J, Kim S, Lee JR, Yoon J, Park D, Sheng M, Kim E.

J Biol Chem. 2003 May 23;278(21):19220-9. Epub 2003 Mar 7.


Cryptic Rac-binding and p21(Cdc42Hs/Rac)-activated kinase phosphorylation sites of NADPH oxidase component p67(phox).

Ahmed S, Prigmore E, Govind S, Veryard C, Kozma R, Wientjes FB, Segal AW, Lim L.

J Biol Chem. 1998 Jun 19;273(25):15693-701.


Crystal structure of the SH3 domain of betaPIX in complex with a high affinity peptide from PAK2.

Hoelz A, Janz JM, Lawrie SD, Corwin B, Lee A, Sakmar TP.

J Mol Biol. 2006 Apr 28;358(2):509-22. Epub 2006 Feb 28.


Structural requirements for PAK activation by Rac GTPases.

Knaus UG, Wang Y, Reilly AM, Warnock D, Jackson JH.

J Biol Chem. 1998 Aug 21;273(34):21512-8.


Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling.

Turner CE, Brown MC, Perrotta JA, Riedy MC, Nikolopoulos SN, McDonald AR, Bagrodia S, Thomas S, Leventhal PS.

J Cell Biol. 1999 May 17;145(4):851-63.


Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes.

Manser E, Huang HY, Loo TH, Chen XQ, Dong JM, Leung T, Lim L.

Mol Cell Biol. 1997 Mar;17(3):1129-43.


Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family.

Manser E, Chong C, Zhao ZS, Leung T, Michael G, Hall C, Lim L.

J Biol Chem. 1995 Oct 20;270(42):25070-8.


BetaPix-enhanced p38 activation by Cdc42/Rac/PAK/MKK3/6-mediated pathway. Implication in the regulation of membrane ruffling.

Lee SH, Eom M, Lee SJ, Kim S, Park HJ, Park D.

J Biol Chem. 2001 Jul 6;276(27):25066-72. Epub 2001 Apr 17.


p85 beta-PIX is required for cell motility through phosphorylations of focal adhesion kinase and p38 MAP kinase.

Lee J, Jung ID, Chang WK, Park CG, Cho DY, Shin EY, Seo DW, Kim YK, Lee HW, Han JW, Lee HY.

Exp Cell Res. 2005 Jul 15;307(2):315-28.


A novel regulator of p21-activated kinases.

Bagrodia S, Taylor SJ, Jordon KA, Van Aelst L, Cerione RA.

J Biol Chem. 1998 Sep 11;273(37):23633-6.


PAK promotes morphological changes by acting upstream of Rac.

Obermeier A, Ahmed S, Manser E, Yen SC, Hall C, Lim L.

EMBO J. 1998 Aug 3;17(15):4328-39.


Coupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassembly.

Zhao ZS, Manser E, Loo TH, Lim L.

Mol Cell Biol. 2000 Sep;20(17):6354-63.

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