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Results: 1 to 20 of 182

2.

Analysis of fluoromethyl group chirality establishes a common stereochemical course for the enolpyruvyl transfers catalyzed by EPSP synthase and UDP-GlcNAc enolpyruvyl transferase.

Kim DH, Tucker-Kellogg GW, Lees WJ, Walsh CT.

Biochemistry. 1996 Apr 30;35(17):5435-40.

PMID:
8611533
[PubMed - indexed for MEDLINE]
3.
4.

Structure of UDP-N-acetylglucosamine enolpyruvyl transferase, an enzyme essential for the synthesis of bacterial peptidoglycan, complexed with substrate UDP-N-acetylglucosamine and the drug fosfomycin.

Skarzynski T, Mistry A, Wonacott A, Hutchinson SE, Kelly VA, Duncan K.

Structure. 1996 Dec 15;4(12):1465-74.

PMID:
8994972
[PubMed - indexed for MEDLINE]
5.

Evidence of kinetic control of ligand binding and staged product release in MurA (enolpyruvyl UDP-GlcNAc synthase)-catalyzed reactions .

Jackson SG, Zhang F, Chindemi P, Junop MS, Berti PJ.

Biochemistry. 2009 Dec 15;48(49):11715-23. doi: 10.1021/bi901524q.

PMID:
19899805
[PubMed - indexed for MEDLINE]
6.

Evidence that the fosfomycin target Cys115 in UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is essential for product release.

Eschenburg S, Priestman M, Schönbrunn E.

J Biol Chem. 2005 Feb 4;280(5):3757-63. Epub 2004 Nov 5.

PMID:
15531591
[PubMed - indexed for MEDLINE]
Free Article
7.

Detection and characterization of a phospholactoyl-enzyme adduct in the reaction catalyzed by UDP-N-acetylglucosamine enolpyruvoyl transferase, MurZ.

Brown ED, Marquardt JL, Lee JP, Walsh CT, Anderson KS.

Biochemistry. 1994 Sep 6;33(35):10638-45.

PMID:
8075064
[PubMed - indexed for MEDLINE]
8.

Asparagine 23 and aspartate 305 are essential residues in the active site of UDP-N-acetylglucosamine enolpyruvyl transferase from Enterobacter cloacae.

Samland AK, Etezady-Esfarjani T, Amrhein N, Macheroux P.

Biochemistry. 2001 Feb 13;40(6):1550-9.

PMID:
11327813
[PubMed - indexed for MEDLINE]
10.
11.

Role of the loop containing residue 115 in the induced-fit mechanism of the bacterial cell wall biosynthetic enzyme MurA.

Schönbrunn E, Eschenburg S, Krekel F, Luger K, Amrhein N.

Biochemistry. 2000 Mar 7;39(9):2164-73.

PMID:
10694381
[PubMed - indexed for MEDLINE]
12.

Detection of the covalent intermediate of UDP-N-acetylglucosamine enolpyruvyl transferase by solution-state and time-resolved solid-state NMR spectroscopy.

Ramilo C, Appleyard RJ, Wanke C, Krekel F, Amrhein N, Evans JN.

Biochemistry. 1994 Dec 20;33(50):15071-9.

PMID:
7999765
[PubMed - indexed for MEDLINE]
13.

Functional consequence of covalent reaction of phosphoenolpyruvate with UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA).

Zhu JY, Yang Y, Han H, Betzi S, Olesen SH, Marsilio F, Schönbrunn E.

J Biol Chem. 2012 Apr 13;287(16):12657-67. doi: 10.1074/jbc.M112.342725. Epub 2012 Feb 29.

PMID:
22378791
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A novel inhibitor that suspends the induced fit mechanism of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA).

Eschenburg S, Priestman MA, Abdul-Latif FA, Delachaume C, Fassy F, Schönbrunn E.

J Biol Chem. 2005 Apr 8;280(14):14070-5. Epub 2005 Feb 8.

PMID:
15701635
[PubMed - indexed for MEDLINE]
Free Article
15.

Studies on the conformational changes in the bacterial cell wall biosynthetic enzyme UDP-N-acetylglucosamine enolpyruvyltransferase (MurA).

Schönbrunn E, Svergun DI, Amrhein N, Koch MH.

Eur J Biochem. 1998 Apr 15;253(2):406-12.

PMID:
9654090
[PubMed - indexed for MEDLINE]
Free Article
16.
17.

MurA (MurZ), the enzyme that catalyzes the first committed step in peptidoglycan biosynthesis, is essential in Escherichia coli.

Brown ED, Vivas EI, Walsh CT, Kolter R.

J Bacteriol. 1995 Jul;177(14):4194-7.

PMID:
7608103
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enolpyruvyl transferase.

Thomas AM, Ginj C, Jelesarov I, Amrhein N, Macheroux P.

Eur J Biochem. 2004 Jul;271(13):2682-90.

PMID:
15206933
[PubMed - indexed for MEDLINE]
Free Article
19.

UDP-N-acetylmuramic acid (UDP-MurNAc) is a potent inhibitor of MurA (enolpyruvyl-UDP-GlcNAc synthase).

Mizyed S, Oddone A, Byczynski B, Hughes DW, Berti PJ.

Biochemistry. 2005 Mar 15;44(10):4011-7.

PMID:
15751977
[PubMed - indexed for MEDLINE]
20.

Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis.

Guo RT, Ko TP, Chen AP, Kuo CJ, Wang AH, Liang PH.

J Biol Chem. 2005 May 27;280(21):20762-74. Epub 2005 Mar 23.

PMID:
15788389
[PubMed - indexed for MEDLINE]
Free Article

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