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Items: 1 to 20 of 107


An induced proximity model for caspase-8 activation.

Muzio M, Stockwell BR, Stennicke HR, Salvesen GS, Dixit VM.

J Biol Chem. 1998 Jan 30;273(5):2926-30.


FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

Medema JP, Scaffidi C, Kischkel FC, Shevchenko A, Mann M, Krammer PH, Peter ME.

EMBO J. 1997 May 15;16(10):2794-804.


Protein kinase C regulates FADD recruitment and death-inducing signaling complex formation in Fas/CD95-induced apoptosis.

Gómez-Angelats M, Cidlowski JA.

J Biol Chem. 2001 Nov 30;276(48):44944-52. Epub 2001 Oct 1.


FLICE induced apoptosis in a cell-free system. Cleavage of caspase zymogens.

Muzio M, Salvesen GS, Dixit VM.

J Biol Chem. 1997 Jan 31;272(5):2952-6.


Apoptosis induced by a chimeric Fas/FLICE receptor: lack of requirement for Fas- or FADD-binding proteins.

Memon SA, Hou J, Moreno MB, Zacharchuk CM.

J Immunol. 1998 Mar 1;160(5):2046-9.


Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex.

Rasper DM, Vaillancourt JP, Hadano S, Houtzager VM, Seiden I, Keen SL, Tawa P, Xanthoudakis S, Nasir J, Martindale D, Koop BF, Peterson EP, Thornberry NA, Huang J, MacPherson DP, Black SC, Hornung F, Lenardo MJ, Hayden MR, Roy S, Nicholson DW.

Cell Death Differ. 1998 Apr;5(4):271-88.


NMR structure and mutagenesis of the FADD (Mort1) death-effector domain.

Eberstadt M, Huang B, Chen Z, Meadows RP, Ng SC, Zheng L, Lenardo MJ, Fesik SW.

Nature. 1998 Apr 30;392(6679):941-5.


Fas-associated death domain protein (FADD) and caspase-8 mediate up-regulation of c-Fos by Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) via a FLICE inhibitory protein (FLIP)-regulated pathway.

Siegmund D, Mauri D, Peters N, Juo P, Thome M, Reichwein M, Blenis J, Scheurich P, Tschopp J, Wajant H.

J Biol Chem. 2001 Aug 31;276(35):32585-90. Epub 2001 May 30.


FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.

Muzio M, Chinnaiyan AM, Kischkel FC, O'Rourke K, Shevchenko A, Ni J, Scaffidi C, Bretz JD, Zhang M, Gentz R, Mann M, Krammer PH, Peter ME, Dixit VM.

Cell. 1996 Jun 14;85(6):817-27.


The role of c-FLIP in modulation of CD95-induced apoptosis.

Scaffidi C, Schmitz I, Krammer PH, Peter ME.

J Biol Chem. 1999 Jan 15;274(3):1541-8.


Fas-associated death domain protein is a Fas-mediated apoptosis modulator in synoviocytes.

Okamoto K, Kobayashi T, Kobata T, Hasunuma T, Kato T, Sumida T, Nishioka K.

Rheumatology (Oxford). 2000 May;39(5):471-80.


Two CD95 (APO-1/Fas) signaling pathways.

Scaffidi C, Fulda S, Srinivasan A, Friesen C, Li F, Tomaselli KJ, Debatin KM, Krammer PH, Peter ME.

EMBO J. 1998 Mar 16;17(6):1675-87.


Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

Wieder T, Essmann F, Prokop A, Schmelz K, Schulze-Osthoff K, Beyaert R, Dörken B, Daniel PT.

Blood. 2001 Mar 1;97(5):1378-87.


The recruitment of Fas-associated death domain/caspase-8 in Ras-induced apoptosis.

Chen CY, Juo P, Liou JS, Li CQ, Yu Q, Blenis J, Faller DV.

Cell Growth Differ. 2001 Jun;12(6):297-306.

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