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Items: 1 to 20 of 107

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The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death.

Yan B, Zemskova M, Holder S, Chin V, Kraft A, Koskinen PJ, Lilly M.

J Biol Chem. 2003 Nov 14;278(46):45358-67. Epub 2003 Sep 3.

5.

Pim-1 kinase protects hematopoietic FDC cells from genotoxin-induced death.

Pircher TJ, Zhao S, Geiger JN, Joneja B, Wojchowski DM.

Oncogene. 2000 Jul 27;19(32):3684-92.

6.

ETK2 receptor tyrosine kinase promotes survival of factor-dependent FDC-P1 progenitor cells.

Darby C, Giannola DM, Couzens MS, Emerson SG.

Exp Hematol. 2000 Jun;28(6):716-25.

PMID:
10880758
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Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site.

Aho TL, Sandholm J, Peltola KJ, Mankonen HP, Lilly M, Koskinen PJ.

FEBS Lett. 2004 Jul 30;571(1-3):43-9.

10.

STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells.

Nosaka T, Kawashima T, Misawa K, Ikuta K, Mui AL, Kitamura T.

EMBO J. 1999 Sep 1;18(17):4754-65.

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Phosphatidylinositol 3-kinase is essential for kit ligand-mediated survival, whereas interleukin-3 and flt3 ligand induce expression of antiapoptotic Bcl-2 family genes.

Karlsson R, Engström M, Jönsson M, Karlberg P, Pronk CJ, Richter J, Jönsson JI.

J Leukoc Biol. 2003 Nov;74(5):923-31. Epub 2003 Aug 1.

13.

Cooperative and redundant effects of STAT5 and Ras signaling in BCR/ABL transformed hematopoietic cells.

Hoover RR, Gerlach MJ, Koh EY, Daley GQ.

Oncogene. 2001 Sep 13;20(41):5826-35.

14.

Growth factor modulation of p53-mediated growth arrest versus apoptosis.

Canman CE, Gilmer TM, Coutts SB, Kastan MB.

Genes Dev. 1995 Mar 1;9(5):600-11.

15.

Pim-1 levels determine the size of early B lymphoid compartments in bone marrow.

Domen J, van der Lugt NM, Acton D, Laird PW, Linders K, Berns A.

J Exp Med. 1993 Nov 1;178(5):1665-73.

16.

Targeting PIM kinases impairs survival of hematopoietic cells transformed by kinase inhibitor-sensitive and kinase inhibitor-resistant forms of Fms-like tyrosine kinase 3 and BCR/ABL.

Adam M, Pogacic V, Bendit M, Chappuis R, Nawijn MC, Duyster J, Fox CJ, Thompson CB, Cools J, Schwaller J.

Cancer Res. 2006 Apr 1;66(7):3828-35.

17.

The serine/threonine kinase Pim-2 is a novel anti-apoptotic mediator in myeloma cells.

Asano J, Nakano A, Oda A, Amou H, Hiasa M, Takeuchi K, Miki H, Nakamura S, Harada T, Fujii S, Kagawa K, Endo I, Yata K, Sakai A, Ozaki S, Matsumoto T, Abe M.

Leukemia. 2011 Jul;25(7):1182-8. doi: 10.1038/leu.2011.60. Epub 2011 Apr 8.

PMID:
21475253
19.

Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival.

Hammerman PS, Fox CJ, Birnbaum MJ, Thompson CB.

Blood. 2005 Jun 1;105(11):4477-83. Epub 2005 Feb 10.

20.

CD40 signaling in B cells regulates the expression of the Pim-1 kinase via the NF-kappa B pathway.

Zhu N, Ramirez LM, Lee RL, Magnuson NS, Bishop GA, Gold MR.

J Immunol. 2002 Jan 15;168(2):744-54.

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