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Items: 1 to 20 of 236

1.

Transgenic knockout mice with exclusively human sickle hemoglobin and sickle cell disease.

Pászty C, Brion CM, Manci E, Witkowska HE, Stevens ME, Mohandas N, Rubin EM.

Science. 1997 Oct 31;278(5339):876-8.

2.

Knockout-transgenic mouse model of sickle cell disease.

Ryan TM, Ciavatta DJ, Townes TM.

Science. 1997 Oct 31;278(5339):873-6.

3.

Transgenic knockout mice exclusively expressing human hemoglobin S after transfer of a 240-kb betas-globin yeast artificial chromosome: A mouse model of sickle cell anemia.

Chang JC, Lu R, Lin C, Xu SM, Kan YW, Porcu S, Carlson E, Kitamura M, Yang S, Flebbe-Rehwaldt L, Gaensler KM.

Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14886-90.

4.

A recombinant human hemoglobin with anti-sickling properties greater than fetal hemoglobin.

Levasseur DN, Ryan TM, Reilly MP, McCune SL, Asakura T, Townes TM.

J Biol Chem. 2004 Jun 25;279(26):27518-24. Epub 2004 Apr 14.

5.

Mouse models of sickle cell disease.

Beuzard Y.

Transfus Clin Biol. 2008 Feb-Mar;15(1-2):7-11. doi: 10.1016/j.tracli.2008.04.001. Epub 2008 May 27.

PMID:
18502677
6.

A second generation transgenic mouse model expressing both hemoglobin S (HbS) and HbS-Antilles results in increased phenotypic severity.

Fabry ME, Sengupta A, Suzuka SM, Costantini F, Rubin EM, Hofrichter J, Christoph G, Manci E, Culberson D, Factor SM, Nagel RL.

Blood. 1995 Sep 15;86(6):2419-28.

7.

Magnetic resonance evidence of hypoxia in a homozygous alpha-knockout of a transgenic mouse model for sickle cell disease.

Fabry ME, Kennan RP, Paszty C, Costantini F, Rubin EM, Gore JC, Nagel RL.

J Clin Invest. 1996 Dec 1;98(11):2450-5.

8.

Second generation knockout sickle mice: the effect of HbF.

Fabry ME, Suzuka SM, Weinberg RS, Lawrence C, Factor SM, Gilman JG, Costantini F, Nagel RL.

Blood. 2001 Jan 15;97(2):410-8.

9.

Human sickle hemoglobin in transgenic mice.

Ryan TM, Townes TM, Reilly MP, Asakura T, Palmiter RD, Brinster RL, Behringer RR.

Science. 1990 Feb 2;247(4942):566-8.

PMID:
2154033
10.

Transgenic mouse models of sickle cell disease.

Beuzard Y.

Curr Opin Hematol. 1996 Mar;3(2):150-5. Review.

PMID:
9372066
11.

Short survival of phosphatidylserine-exposing red blood cells in murine sickle cell anemia.

de Jong K, Emerson RK, Butler J, Bastacky J, Mohandas N, Kuypers FA.

Blood. 2001 Sep 1;98(5):1577-84.

12.

Effect of fetal hemoglobin on microvascular regulation in sickle transgenic-knockout mice.

Kaul DK, Liu XD, Chang HY, Nagel RL, Fabry ME.

J Clin Invest. 2004 Oct;114(8):1136-45.

13.

A transgenic mouse model of sickle cell disorder.

Greaves DR, Fraser P, Vidal MA, Hedges MJ, Ropers D, Luzzatto L, Grosveld F.

Nature. 1990 Jan 11;343(6254):183-5.

PMID:
2296310
14.

Towards a transgenic mouse model of sickle cell disease: hemoglobin SAD.

Trudel M, Saadane N, Garel MC, Bardakdjian-Michau J, Blouquit Y, Guerquin-Kern JL, Rouyer-Fessard P, Vidaud D, Pachnis A, Roméo PH, et al.

EMBO J. 1991 Nov;10(11):3157-65.

15.

Pathophysiology of a sickle cell trait mouse model: human alpha(beta)(S) transgenes with one mouse beta-globin allele.

Noguchi CT, Gladwin M, Diwan B, Merciris P, Smith R, Yu X, Buzard G, Fitzhugh A, Keefer LK, Schechter AN, Mohandas N.

Blood Cells Mol Dis. 2001 Nov-Dec;27(6):971-7.

PMID:
11831863
16.
17.
18.

Introduction and expression of the human Bs-globin gene in transgenic mice.

Rubin EM, Lu RH, Cooper S, Mohandas N, Kan YW.

Am J Hum Genet. 1988 Apr;42(4):585-91.

19.

Anti-beta s-ribozyme reduces beta s mRNA levels in transgenic mice: potential application to the gene therapy of sickle cell anemia.

Alami R, Gilman JG, Feng YQ, Marmorato A, Rochlin I, Suzuka SM, Fabry ME, Nagel RL, Bouhassira EE.

Blood Cells Mol Dis. 1999 Apr;25(2):110-9.

PMID:
10389593
20.
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