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Results: 1 to 20 of 235

1.

Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function.

Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS.

Nature. 1997 Oct 9;389(6651):610-4.

PMID:
9335502
[PubMed - indexed for MEDLINE]
3.

Amelioration of insulin resistance in diabetic ob/ob mice by a new type of orally active insulin-mimetic vanadyl complex: bis(1-oxy-2-pyridinethiolato)oxovanadium(IV) with VO(S(2)O(2)) coordination mode.

Takeshita S, Kawamura I, Yasuno T, Kimura C, Yamamoto T, Seki J, Tamura A, Sakurai H, Goto T.

J Inorg Biochem. 2001 Jun;85(2-3):179-86.

PMID:
11410238
[PubMed - indexed for MEDLINE]
4.

Obesity and diabetes in TNF-alpha receptor- deficient mice.

Schreyer SA, Chua SC Jr, LeBoeuf RC.

J Clin Invest. 1998 Jul 15;102(2):402-11.

PMID:
9664082
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein.

Hotamisligil GS, Johnson RS, Distel RJ, Ellis R, Papaioannou VE, Spiegelman BM.

Science. 1996 Nov 22;274(5291):1377-9.

PMID:
8910278
[PubMed - indexed for MEDLINE]
7.

Mechanisms of TNF-alpha-induced insulin resistance.

Hotamisligil GS.

Exp Clin Endocrinol Diabetes. 1999;107(2):119-25. Review.

PMID:
10320052
[PubMed - indexed for MEDLINE]
8.

Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha.

Hotamisligil GS, Budavari A, Murray D, Spiegelman BM.

J Clin Invest. 1994 Oct;94(4):1543-9.

PMID:
7523453
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Expression pattern of tumour necrosis factor receptors in subcutaneous and omental human adipose tissue: role of obesity and non-insulin-dependent diabetes mellitus.

Hube F, Birgel M, Lee YM, Hauner H.

Eur J Clin Invest. 1999 Aug;29(8):672-8.

PMID:
10457150
[PubMed - indexed for MEDLINE]
10.

Insulin resistance induced by tumor necrosis factor-alpha in myocytes and brown adipocytes.

Lorenzo M, Fernández-Veledo S, Vila-Bedmar R, Garcia-Guerra L, De Alvaro C, Nieto-Vazquez I.

J Anim Sci. 2008 Apr;86(14 Suppl):E94-104. Epub 2007 Oct 16. Review.

PMID:
17940160
[PubMed - indexed for MEDLINE]
Free Article
11.

Insulin resistance associated to obesity: the link TNF-alpha.

Nieto-Vazquez I, Fernández-Veledo S, Krämer DK, Vila-Bedmar R, Garcia-Guerra L, Lorenzo M.

Arch Physiol Biochem. 2008 Jul;114(3):183-94. doi: 10.1080/13813450802181047 . Review. Erratum in: Arch Physiol Biochem. 2009 May;115(2):117.

PMID:
18629684
[PubMed - indexed for MEDLINE]
12.

Inhibition of insulin receptor signaling by TNF: potential role in obesity and non-insulin-dependent diabetes mellitus.

Skolnik EY, Marcusohn J.

Cytokine Growth Factor Rev. 1996 Aug;7(2):161-73. Review.

PMID:
8899294
[PubMed - indexed for MEDLINE]
13.
14.

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.

Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM.

J Clin Invest. 1995 May;95(5):2409-15.

PMID:
7738205
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Mechanism of amelioration of insulin resistance by beta3-adrenoceptor agonist AJ-9677 in the KK-Ay/Ta diabetic obese mouse model.

Kato H, Ohue M, Kato K, Nomura A, Toyosawa K, Furutani Y, Kimura S, Kadowaki T.

Diabetes. 2001 Jan;50(1):113-22.

PMID:
11147775
[PubMed - indexed for MEDLINE]
Free Article
16.

A defect in the activity of Delta6 and Delta5 desaturases may be a factor predisposing to the development of insulin resistance syndrome.

Das UN.

Prostaglandins Leukot Essent Fatty Acids. 2005 May;72(5):343-50. Review.

PMID:
15850715
[PubMed - indexed for MEDLINE]
17.

Targeted disruption of the tumor necrosis factor-alpha gene: metabolic consequences in obese and nonobese mice.

Ventre J, Doebber T, Wu M, MacNaul K, Stevens K, Pasparakis M, Kollias G, Moller DE.

Diabetes. 1997 Sep;46(9):1526-31.

PMID:
9287059
[PubMed - indexed for MEDLINE]
18.

SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice.

Emanuelli B, Peraldi P, Filloux C, Chavey C, Freidinger K, Hilton DJ, Hotamisligil GS, Van Obberghen E.

J Biol Chem. 2001 Dec 21;276(51):47944-9. Epub 2001 Oct 16.

PMID:
11604392
[PubMed - indexed for MEDLINE]
Free Article
19.

Functional analysis of tumor necrosis factor (TNF) receptors in TNF-alpha-mediated insulin resistance in genetic obesity.

Uysal KT, Wiesbrock SM, Hotamisligil GS.

Endocrinology. 1998 Dec;139(12):4832-8.

PMID:
9832419
[PubMed - indexed for MEDLINE]
20.

Tumor necrosis factor-alpha-induced insulin resistance in adipocytes.

Qi C, Pekala PH.

Proc Soc Exp Biol Med. 2000 Feb;223(2):128-35. Review.

PMID:
10654615
[PubMed - indexed for MEDLINE]

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