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Items: 1 to 20 of 185

1.

A major role for CYP2A6 in nicotine C-oxidation by human liver microsomes.

Messina ES, Tyndale RF, Sellers EM.

J Pharmacol Exp Ther. 1997 Sep;282(3):1608-14.

2.

Role of human cytochrome P4502A6 in C-oxidation of nicotine.

Nakajima M, Yamamoto T, Nunoya K, Yokoi T, Nagashima K, Inoue K, Funae Y, Shimada N, Kamataki T, Kuroiwa Y.

Drug Metab Dispos. 1996 Nov;24(11):1212-7.

PMID:
8937855
3.

Roles of CYP2A6 and CYP2B6 in nicotine C-oxidation by human liver microsomes.

Yamazaki H, Inoue K, Hashimoto M, Shimada T.

Arch Toxicol. 1999 Mar;73(2):65-70.

PMID:
10350185
4.

Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes.

Nakajima M, Yamamoto T, Nunoya K, Yokoi T, Nagashima K, Inoue K, Funae Y, Shimada N, Kamataki T, Kuroiwa Y.

J Pharmacol Exp Ther. 1996 May;277(2):1010-5.

PMID:
8627511
5.

Evaluation of methoxsalen, tranylcypromine, and tryptamine as specific and selective CYP2A6 inhibitors in vitro.

Zhang W, Kilicarslan T, Tyndale RF, Sellers EM.

Drug Metab Dispos. 2001 Jun;29(6):897-902.

6.

CYP2A6 AND CYP2B6 are involved in nornicotine formation from nicotine in humans: interindividual differences in these contributions.

Yamanaka H, Nakajima M, Fukami T, Sakai H, Nakamura A, Katoh M, Takamiya M, Aoki Y, Yokoi T.

Drug Metab Dispos. 2005 Dec;33(12):1811-8. Epub 2005 Aug 31.

7.
8.

Variable contribution of cytochromes P450 2D6, 2C9 and 3A4 to the 4-hydroxylation of tamoxifen by human liver microsomes.

Crewe HK, Ellis SW, Lennard MS, Tucker GT.

Biochem Pharmacol. 1997 Jan 24;53(2):171-8.

PMID:
9037249
9.

Multiple human cytochromes contribute to biotransformation of dextromethorphan in-vitro: role of CYP2C9, CYP2C19, CYP2D6, and CYP3A.

von Moltke LL, Greenblatt DJ, Grassi JM, Granda BW, Venkatakrishnan K, Schmider J, Harmatz JS, Shader RI.

J Pharm Pharmacol. 1998 Sep;50(9):997-1004.

PMID:
9811160
10.

Halofantrine metabolism in microsomes in man: major role of CYP 3A4 and CYP 3A5.

Baune B, Flinois JP, Furlan V, Gimenez F, Taburet AM, Becquemont L, Farinotti R.

J Pharm Pharmacol. 1999 Apr;51(4):419-26.

PMID:
10385214
11.

Inhibition of coumarin 7-hydroxylase activity in human liver microsomes.

Draper AJ, Madan A, Parkinson A.

Arch Biochem Biophys. 1997 May 1;341(1):47-61.

PMID:
9143352
12.

Inhibitory effects of neurotransmitters and steroids on human CYP2A6.

Higashi E, Nakajima M, Katoh M, Tokudome S, Yokoi T.

Drug Metab Dispos. 2007 Apr;35(4):508-14. Epub 2007 Jan 19.

13.
14.

Methadone N-demethylation in human liver microsomes: lack of stereoselectivity and involvement of CYP3A4.

Foster DJ, Somogyi AA, Bochner F.

Br J Clin Pharmacol. 1999 Apr;47(4):403-12.

15.

Human cytochrome P450 isozymes in metabolism and health effects of gasoline ethers.

Hong JY, Wang YY, Mohr SN, Bondoc FY, Deng C.

Res Rep Health Eff Inst. 2001 May;(102):7-27; discussion 95-109.

PMID:
11504148
16.

Nicotine 5'-oxidation and methyl oxidation by P450 2A enzymes.

Murphy SE, Raulinaitis V, Brown KM.

Drug Metab Dispos. 2005 Aug;33(8):1166-73. Epub 2005 Apr 28.

18.

Relationship between interindividual differences in nicotine metabolism and CYP2A6 genetic polymorphism in humans.

Nakajima M, Kwon JT, Tanaka N, Zenta T, Yamamoto Y, Yamamoto H, Yamazaki H, Yamamoto T, Kuroiwa Y, Yokoi T.

Clin Pharmacol Ther. 2001 Jan;69(1):72-8.

PMID:
11180041
19.

(+)-cis-3,5-dimethyl-2-(3-pyridyl) thiazolidin-4-one hydrochloride (SM-12502) as a novel substrate for cytochrome P450 2A6 in human liver microsomes.

Nunoya K, Yokoi Y, Kimura K, Kodama T, Funayama M, Inoue K, Nagashima K, Funae Y, Shimada N, Green C, Kamataki T.

J Pharmacol Exp Ther. 1996 May;277(2):768-74.

PMID:
8627557
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