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Results: 1 to 20 of 160

1.

Human UGT2B7 catalyzes morphine glucuronidation.

Coffman BL, Rios GR, King CD, Tephly TR.

Drug Metab Dispos. 1997 Jan;25(1):1-4.

PMID:
9010622
[PubMed - indexed for MEDLINE]
Free Article
2.

Epirubicin glucuronidation is catalyzed by human UDP-glucuronosyltransferase 2B7.

Innocenti F, Iyer L, Ramírez J, Green MD, Ratain MJ.

Drug Metab Dispos. 2001 May;29(5):686-92.

PMID:
11302935
[PubMed - indexed for MEDLINE]
Free Article
3.

The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268).

Coffman BL, King CD, Rios GR, Tephly TR.

Drug Metab Dispos. 1998 Jan;26(1):73-7.

PMID:
9443856
[PubMed - indexed for MEDLINE]
Free Article
4.

Modulation of UDP-glucuronosyltransferase function by cytochrome P450: evidence for the alteration of UGT2B7-catalyzed glucuronidation of morphine by CYP3A4.

Takeda S, Ishii Y, Iwanaga M, Mackenzie PI, Nagata K, Yamazoe Y, Oguri K, Yamada H.

Mol Pharmacol. 2005 Mar;67(3):665-72. Epub 2004 Dec 20.

PMID:
15611481
[PubMed - indexed for MEDLINE]
Free Article
5.

Evaluation of 3'-azido-3'-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2 polymorphism.

Court MH, Krishnaswamy S, Hao Q, Duan SX, Patten CJ, Von Moltke LL, Greenblatt DJ.

Drug Metab Dispos. 2003 Sep;31(9):1125-33.

PMID:
12920168
[PubMed - indexed for MEDLINE]
Free Article
6.

Regioselective glucuronidation of denopamine: marked species differences and identification of human udp-glucuronosyltransferase isoform.

Kaji H, Kume T.

Drug Metab Dispos. 2005 Mar;33(3):403-12. Epub 2004 Dec 17.

PMID:
15608137
[PubMed - indexed for MEDLINE]
Free Article
7.

Characterization of rat and human UDP-glucuronosyltransferases responsible for the in vitro glucuronidation of diclofenac.

King C, Tang W, Ngui J, Tephly T, Braun M.

Toxicol Sci. 2001 May;61(1):49-53.

PMID:
11294973
[PubMed - indexed for MEDLINE]
Free Article
8.

The glucuronidation of morphine by dog liver microsomes: identification of morphine-6-O-glucuronide.

King C, Finley B, Franklin R.

Drug Metab Dispos. 2000 Jun;28(6):661-3.

PMID:
10820138
[PubMed - indexed for MEDLINE]
Free Article
9.

Isoform selectivity and kinetics of morphine 3- and 6-glucuronidation by human udp-glucuronosyltransferases: evidence for atypical glucuronidation kinetics by UGT2B7.

Stone AN, Mackenzie PI, Galetin A, Houston JB, Miners JO.

Drug Metab Dispos. 2003 Sep;31(9):1086-9. Erratum in: Drug Metab Dispos. 2003 Dec;31(12):1541.

PMID:
12920162
[PubMed - indexed for MEDLINE]
Free Article
10.

Identification of human UGT2B7 as the major isoform involved in the O-glucuronidation of chloramphenicol.

Chen M, LeDuc B, Kerr S, Howe D, Williams DA.

Drug Metab Dispos. 2010 Mar;38(3):368-75. doi: 10.1124/dmd.109.029900. Epub 2009 Dec 11.

PMID:
20008037
[PubMed - indexed for MEDLINE]
Free Article
11.

Glucuronidation of 1'-hydroxyestragole (1'-HE) by human UDP-glucuronosyltransferases UGT2B7 and UGT1A9.

Iyer LV, Ho MN, Shinn WM, Bradford WW, Tanga MJ, Nath SS, Green CE.

Toxicol Sci. 2003 May;73(1):36-43. Epub 2003 Mar 25.

PMID:
12657745
[PubMed - indexed for MEDLINE]
Free Article
12.

The UDP-glucuronosyltransferase 2B7 isozyme is responsible for gemfibrozil glucuronidation in the human liver.

Mano Y, Usui T, Kamimura H.

Drug Metab Dispos. 2007 Nov;35(11):2040-4. Epub 2007 Aug 1.

PMID:
17670842
[PubMed - indexed for MEDLINE]
Free Article
13.

Inhibition of UDP-glucuronosyltransferase 2b7-catalyzed morphine glucuronidation by ketoconazole: dual mechanisms involving a novel noncompetitive mode.

Takeda S, Kitajima Y, Ishii Y, Nishimura Y, Mackenzie PI, Oguri K, Yamada H.

Drug Metab Dispos. 2006 Aug;34(8):1277-82. Epub 2006 May 5.

PMID:
16679387
[PubMed - indexed for MEDLINE]
Free Article
14.

Cloning and characterisation of the first drug-metabolising canine UDP-glucuronosyltransferase of the 2B subfamily.

Soars MG, Fettes M, O'Sullivan AC, Riley RJ, Ethell BT, Burchell B.

Biochem Pharmacol. 2003 Apr 15;65(8):1251-9.

PMID:
12694866
[PubMed - indexed for MEDLINE]
15.

Purification of a phenobarbital-inducible UDP-glucuronosyltransferase isoform from dog liver which catalyzes morphine and testosterone glucuronidation.

Oguri K, Kurogi A, Yamabe K, Tanaka M, Yoshisue K, Ishii Y, Yoshimura H.

Arch Biochem Biophys. 1996 Jan 15;325(2):159-66.

PMID:
8561493
[PubMed - indexed for MEDLINE]
16.

Predominant contribution of UDP-glucuronosyltransferase 2B7 in the glucuronidation of racemic flurbiprofen in the human liver.

Mano Y, Usui T, Kamimura H.

Drug Metab Dispos. 2007 Jul;35(7):1182-7. Epub 2007 Apr 19.

PMID:
17446261
[PubMed - indexed for MEDLINE]
Free Article
17.
18.

3'-azido-3'-deoxythimidine (AZT) is glucuronidated by human UDP-glucuronosyltransferase 2B7 (UGT2B7).

Barbier O, Turgeon D, Girard C, Green MD, Tephly TR, Hum DW, Bélanger A.

Drug Metab Dispos. 2000 May;28(5):497-502.

PMID:
10772627
[PubMed - indexed for MEDLINE]
Free Article
19.
20.

Morphine glucuronidation and glucosidation represent complementary metabolic pathways that are both catalyzed by UDP-glucuronosyltransferase 2B7: kinetic, inhibition, and molecular modeling studies.

Chau N, Elliot DJ, Lewis BC, Burns K, Johnston MR, Mackenzie PI, Miners JO.

J Pharmacol Exp Ther. 2014 Apr;349(1):126-37. doi: 10.1124/jpet.113.212258. Epub 2014 Jan 23.

PMID:
24459244
[PubMed - indexed for MEDLINE]

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