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Results: 1 to 20 of 268

1.

Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux.

Cameron AM, Steiner JP, Roskams AJ, Ali SM, Ronnett GV, Snyder SH.

Cell. 1995 Nov 3;83(3):463-72.

PMID:
8521476
[PubMed - indexed for MEDLINE]
Free Article
2.

Immunophilin FK506 binding protein associated with inositol 1,4,5-trisphosphate receptor modulates calcium flux.

Cameron AM, Steiner JP, Sabatini DM, Kaplin AI, Walensky LD, Snyder SH.

Proc Natl Acad Sci U S A. 1995 Feb 28;92(5):1784-8.

PMID:
7533300
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

A novel FK506 binding protein can mediate the immunosuppressive effects of FK506 and is associated with the cardiac ryanodine receptor.

Lam E, Martin MM, Timerman AP, Sabers C, Fleischer S, Lukas T, Abraham RT, O'Keefe SJ, O'Neill EA, Wiederrecht GJ.

J Biol Chem. 1995 Nov 3;270(44):26511-22.

PMID:
7592869
[PubMed - indexed for MEDLINE]
Free Article
4.

FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domain.

Cameron AM, Nucifora FC Jr, Fung ET, Livingston DJ, Aldape RA, Ross CA, Snyder SH.

J Biol Chem. 1997 Oct 31;272(44):27582-8.

PMID:
9346894
[PubMed - indexed for MEDLINE]
Free Article
5.

In smooth muscle, FK506-binding protein modulates IP3 receptor-evoked Ca2+ release by mTOR and calcineurin.

MacMillan D, Currie S, Bradley KN, Muir TC, McCarron JG.

J Cell Sci. 2005 Dec 1;118(Pt 23):5443-51. Epub 2005 Nov 8.

PMID:
16278292
[PubMed - indexed for MEDLINE]
Free Article
6.

FK506-binding protein (FKBP12) regulates ryanodine receptor-evoked Ca2+ release in colonic but not aortic smooth muscle.

MacMillan D, Currie S, McCarron JG.

Cell Calcium. 2008 Jun;43(6):539-49. Epub 2007 Oct 24.

PMID:
17950843
[PubMed - indexed for MEDLINE]
7.

The immunophilin FK506-binding protein modulates Ca2+ release channel closure in rat heart.

Xiao RP, Valdivia HH, Bogdanov K, Valdivia C, Lakatta EG, Cheng H.

J Physiol. 1997 Apr 15;500 ( Pt 2):343-54.

PMID:
9147322
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein.

Brillantes AB, Ondrias K, Scott A, Kobrinsky E, Ondriasov√° E, Moschella MC, Jayaraman T, Landers M, Ehrlich BE, Marks AR.

Cell. 1994 May 20;77(4):513-23.

PMID:
7514503
[PubMed - indexed for MEDLINE]
9.

Calcineurin regulates ryanodine receptor/Ca(2+)-release channels in rat heart.

Bandyopadhyay A, Shin DW, Ahn JO, Kim DH.

Biochem J. 2000 Nov 15;352 Pt 1:61-70.

PMID:
11062058
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells.

Fruman DA, Bierer BE, Benes JE, Burakoff SJ, Austen KF, Katz HR.

J Immunol. 1995 Feb 15;154(4):1846-51.

PMID:
7530743
[PubMed - indexed for MEDLINE]
11.

FK506 and the role of immunophilins in nerve regeneration.

Gold BG.

Mol Neurobiol. 1997 Dec;15(3):285-306. Review.

PMID:
9457703
[PubMed - indexed for MEDLINE]
12.

FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells.

Fruman DA, Wood MA, Gjertson CK, Katz HR, Burakoff SJ, Bierer BE.

Eur J Immunol. 1995 Feb;25(2):563-71.

PMID:
7533090
[PubMed - indexed for MEDLINE]
13.

Identification of a physical interaction between calcineurin and nuclear factor of activated T cells (NFATp).

Wesselborg S, Fruman DA, Sagoo JK, Bierer BE, Burakoff SJ.

J Biol Chem. 1996 Jan 19;271(3):1274-7.

PMID:
8576111
[PubMed - indexed for MEDLINE]
Free Article
14.

Roles of peptidyl-prolyl cis-trans isomerase and calcineurin in the mechanisms of antimalarial action of cyclosporin A, FK506, and rapamycin.

Bell A, Wernli B, Franklin RM.

Biochem Pharmacol. 1994 Aug 3;48(3):495-503.

PMID:
7520696
[PubMed - indexed for MEDLINE]
15.

FK506 binding protein mutational analysis. Defining the surface residue contributions to stability of the calcineurin co-complex.

Futer O, DeCenzo MT, Aldape RA, Livingston DJ.

J Biol Chem. 1995 Aug 11;270(32):18935-40.

PMID:
7642551
[PubMed - indexed for MEDLINE]
Free Article
16.

Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands.

Cardenas ME, Hemenway C, Muir RS, Ye R, Fiorentino D, Heitman J.

EMBO J. 1994 Dec 15;13(24):5944-57.

PMID:
7529175
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Neural roles of immunophilins and their ligands.

Sabatini DM, Lai MM, Snyder SH.

Mol Neurobiol. 1997 Oct;15(2):223-39. Review.

PMID:
9396011
[PubMed - indexed for MEDLINE]
18.

Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex.

Kissinger CR, Parge HE, Knighton DR, Lewis CT, Pelletier LA, Tempczyk A, Kalish VJ, Tucker KD, Showalter RE, Moomaw EW, et al.

Nature. 1995 Dec 7;378(6557):641-4.

PMID:
8524402
[PubMed - indexed for MEDLINE]
19.

Molecular mechanisms of immunosuppression by cyclosporine, FK506, and rapamycin.

Cardenas ME, Zhu D, Heitman J.

Curr Opin Nephrol Hypertens. 1995 Nov;4(6):472-7. Review.

PMID:
8591053
[PubMed - indexed for MEDLINE]
20.

Calcineurin controls inositol 1,4,5-trisphosphate type 1 receptor expression in neurons.

Genazzani AA, Carafoli E, Guerini D.

Proc Natl Acad Sci U S A. 1999 May 11;96(10):5797-801.

PMID:
10318964
[PubMed - indexed for MEDLINE]
Free PMC Article

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