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Similar articles for PubMed (Select 8248258)


The human beta globin locus introduced by YAC transfer exhibits a specific and reproducible pattern of developmental regulation in transgenic mice.

Porcu S, Kitamura M, Witkowska E, Zhang Z, Mutero A, Lin C, Chang J, Gaensler KM.

Blood. 1997 Dec 1;90(11):4602-9.


Synergistic regulation of human beta-globin gene switching by locus control region elements HS3 and HS4.

Bungert J, Davé U, Lim KC, Lieuw KH, Shavit JA, Liu Q, Engel JD.

Genes Dev. 1995 Dec 15;9(24):3083-96.


Proper developmental control of human globin genes reproduced by transgenic mice containing a 160-kb BAC carrying the human beta-globin locus.

Huang Y, Liu DP, Wu L, Li TC, Wu M, Feng DX, Liang CC.

Blood Cells Mol Dis. 2000 Dec;26(6):598-610.


Sequences in the (A)gamma-delta intergenic region are not required for stage-specific regulation of the human beta-globin gene locus.

Gaensler KM, Zhang Z, Lin C, Yang S, Hardt K, Flebbe-Rehwaldt L.

Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3374-9. Epub 2003 Mar 10.


Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human beta-globin locus display proper developmental control of human globin genes.

Peterson KR, Clegg CH, Huxley C, Josephson BM, Haugen HS, Furukawa T, Stamatoyannopoulos G.

Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7593-7.


Developmental specificity of the interaction between the locus control region and embryonic or fetal globin genes in transgenic mice with an HS3 core deletion.

Navas PA, Peterson KR, Li Q, Skarpidi E, Rohde A, Shaw SE, Clegg CH, Asano H, Stamatoyannopoulos G.

Mol Cell Biol. 1998 Jul;18(7):4188-96.


Correct function of the locus control region may require passage through a nonerythroid cellular environment.

Vassilopoulos G, Navas PA, Skarpidi E, Peterson KR, Lowrey CH, Papayannopoulou T, Stamatoyannopoulos G.

Blood. 1999 Jan 15;93(2):703-12.


Use of yeast artificial chromosomes (YACs) for studying control of gene expression: correct regulation of the genes of a human beta-globin locus YAC following transfer to mouse erythroleukemia cell lines.

Peterson KR, Zitnik G, Huxley C, Lowrey CH, Gnirke A, Leppig KA, Papayannopoulou T, Stamatoyannopoulos G.

Proc Natl Acad Sci U S A. 1993 Dec 1;90(23):11207-11. Erratum in: Proc Natl Acad Sci U S A 1994 Mar 1;91(5):1979.


A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice.

Ryan TM, Behringer RR, Martin NC, Townes TM, Palmiter RD, Brinster RL.

Genes Dev. 1989 Mar;3(3):314-23.


beta-YAC transgenic mice for studying LCR function.

Peterson KR, Navas PA, Stamatoyannopoulos G.

Ann N Y Acad Sci. 1998 Jun 30;850:28-37. Review.


Transgenic analysis of a 100-kb human beta-globin cluster-containing DNA fragment propagated as a bacterial artificial chromosome.

Kaufman RM, Pham CT, Ley TJ.

Blood. 1999 Nov 1;94(9):3178-84. Erratum in: Blood 2000 Feb 1;95(3):744.


Developmental regulation of a complete 70-kb human beta-globin locus in transgenic mice.

Strouboulis J, Dillon N, Grosveld F.

Genes Dev. 1992 Oct;6(10):1857-64.

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