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Receptor-binding, tyrosine phosphorylation and chromosome localization of the mouse SH2-containing phosphotyrosine phosphatase Syp.

Feng GS, Shen R, Heng HH, Tsui LC, Kazlauskas A, Pawson T.

Oncogene. 1994 Jun;9(6):1545-50.


SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases.

Feng GS, Hui CC, Pawson T.

Science. 1993 Mar 12;259(5101):1607-11.


Identification of a putative Syp substrate, the PDGF beta receptor.

Klinghoffer RA, Kazlauskas A.

J Biol Chem. 1995 Sep 22;270(38):22208-17.


The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp.

Kuhné MR, Pawson T, Lienhard GE, Feng GS.

J Biol Chem. 1993 Jun 5;268(16):11479-81.


A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase.

Li W, Nishimura R, Kashishian A, Batzer AG, Kim WJ, Cooper JA, Schlessinger J.

Mol Cell Biol. 1994 Jan;14(1):509-17.


Tyrosine phosphatase SHP-2 is involved in regulation of platelet-derived growth factor-induced migration.

Qi JH, Ito N, Claesson-Welsh L.

J Biol Chem. 1999 May 14;274(20):14455-63.


Localization of the insulin-like growth factor I receptor binding sites for the SH2 domain proteins p85, Syp, and GTPase activating protein.

Seely BL, Reichart DR, Staubs PA, Jhun BH, Hsu D, Maegawa H, Milarski KL, Saltiel AR, Olefsky JM.

J Biol Chem. 1995 Aug 11;270(32):19151-7.


Involvement of SH2-containing phosphotyrosine phosphatase Syp in erythropoietin receptor signal transduction pathways.

Tauchi T, Feng GS, Shen R, Hoatlin M, Bagby GC Jr, Kabat D, Lu L, Broxmeyer HE.

J Biol Chem. 1995 Mar 10;270(10):5631-5.


SH2-containing phosphotyrosine phosphatase Syp is a target of p210bcr-abl tyrosine kinase.

Tauchi T, Feng GS, Shen R, Song HY, Donner D, Pawson T, Broxmeyer HE.

J Biol Chem. 1994 May 27;269(21):15381-7.


The ubiquitously expressed Syp phosphatase interacts with c-kit and Grb2 in hematopoietic cells.

Tauchi T, Feng GS, Marshall MS, Shen R, Mantel C, Pawson T, Broxmeyer HE.

J Biol Chem. 1994 Oct 7;269(40):25206-11.


Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor.

Nishimura R, Li W, Kashishian A, Mondino A, Zhou M, Cooper J, Schlessinger J.

Mol Cell Biol. 1993 Nov;13(11):6889-96.


Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras.

Bennett AM, Tang TL, Sugimoto S, Walsh CT, Neel BG.

Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7335-9.


Localization and down-regulating role of the protein tyrosine phosphatase PTP2C in membrane ruffles of PDGF-stimulated cells.

Cossette LJ, Hoglinger O, Mou L, Shen SH.

Exp Cell Res. 1996 Mar 15;223(2):459-66.


Both SH2 domains are involved in interaction of SHP-1 with the epidermal growth factor receptor but cannot confer receptor-directed activity to SHP-1/SHP-2 chimera.

Tenev T, Keilhack H, Tomic S, Stoyanov B, Stein-Gerlach M, Lammers R, Krivtsov AV, Ullrich A, Böhmer FD.

J Biol Chem. 1997 Feb 28;272(9):5966-73.


SHP-2 binds to Tyr763 and Tyr1009 in the PDGF beta-receptor and mediates PDGF-induced activation of the Ras/MAP kinase pathway and chemotaxis.

Rönnstrand L, Arvidsson AK, Kallin A, Rorsman C, Hellman U, Engström U, Wernstedt C, Heldin CH.

Oncogene. 1999 Jun 24;18(25):3696-702.


Localization of the insulin receptor binding sites for the SH2 domain proteins p85, Syp, and GAP.

Staubs PA, Reichart DR, Saltiel AR, Milarski KL, Maegawa H, Berhanu P, Olefsky JM, Seely BL.

J Biol Chem. 1994 Nov 4;269(44):27186-92.

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