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Items: 1 to 20 of 103

1.

A cell cycle regulator potentially involved in genesis of many tumor types.

Kamb A, Gruis NA, Weaver-Feldhaus J, Liu Q, Harshman K, Tavtigian SV, Stockert E, Day RS 3rd, Johnson BE, Skolnick MH.

Science. 1994 Apr 15;264(5157):436-40.

PMID:
8153634
2.

MTS1/p16/CDKN2 lesions in primary glioblastoma multiforme.

Moulton T, Samara G, Chung WY, Yuan L, Desai R, Sisti M, Bruce J, Tycko B.

Am J Pathol. 1995 Mar;146(3):613-9.

3.

Homozygous deletion of the MTS1/p16 and MTS2/p15 genes and amplification of the CDK4 gene in glioma.

Sonoda Y, Yoshimoto T, Sekiya T.

Oncogene. 1995 Nov 16;11(10):2145-9.

PMID:
7478535
4.

The multiple tumor suppressor 1/cyclin-dependent kinase inhibitor 2 gene in human central nervous system primitive neuroectodermal tumor.

Raffel C, Ueki K, Harsh GR 4th, Louis DN.

Neurosurgery. 1995 May;36(5):971-4; discussion 974-5.

PMID:
7791990
5.

New tumor suppressor may rival p53.

Marx J.

Science. 1994 Apr 15;264(5157):344-5. No abstract available.

PMID:
8153613
6.

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers.

Nobori T, Miura K, Wu DJ, Lois A, Takabayashi K, Carson DA.

Nature. 1994 Apr 21;368(6473):753-6.

PMID:
8152487
7.

Somatic mutations of the MTS (multiple tumor suppressor) 1/CDK4l (cyclin-dependent kinase-4 inhibitor) gene in human primary non-small cell lung carcinomas.

Hayashi N, Sugimoto Y, Tsuchiya E, Ogawa M, Nakamura Y.

Biochem Biophys Res Commun. 1994 Aug 15;202(3):1426-30.

PMID:
8060323
8.

Homozygous deletions but no sequence mutations in coding regions of p15 or p16 in human primary bladder tumors.

Packenham JP, Taylor JA, Anna CH, White CM, Devereux TR.

Mol Carcinog. 1995 Nov;14(3):147-51.

PMID:
7576106
9.

Loss of the cyclin-dependent kinase 4-inhibitor (p16; MTS1) gene is frequent in and highly specific to lymphoid tumors in primary human hematopoietic malignancies.

Ogawa S, Hangaishi A, Miyawaki S, Hirosawa S, Miura Y, Takeyama K, Kamada N, Ohtake S, Uike N, Shimazaki C, et al.

Blood. 1995 Aug 15;86(4):1548-56.

10.

CDKN2 (MTS1) tumor suppressor gene mutations in human tumor cell lines.

Liu Q, Neuhausen S, McClure M, Frye C, Weaver-Feldhaus J, Gruis NA, Eddington K, Allalunis-Turner MJ, Skolnick MH, Fujimura FK, et al.

Oncogene. 1995 Mar 16;10(6):1061-7. Erratum in: Oncogene. 1995 Dec 7;11(11):2455.

PMID:
7700630
11.

Rarity of somatic and germline mutations of the cyclin-dependent kinase 4 inhibitor gene, CDK4I, in melanoma.

Ohta M, Nagai H, Shimizu M, Rasio D, Berd D, Mastrangelo M, Singh AD, Shields JA, Shields CL, Croce CM, et al.

Cancer Res. 1994 Oct 15;54(20):5269-72.

12.

Prevalence of germ-line mutations in p16, p19ARF, and CDK4 in familial melanoma: analysis of a clinic-based population.

FitzGerald MG, Harkin DP, Silva-Arrieta S, MacDonald DJ, Lucchina LC, Unsal H, O'Neill E, Koh J, Finkelstein DM, Isselbacher KJ, Sober AJ, Haber DA.

Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8541-5.

13.

High frequency deletion of the tumour suppressor gene P16INK4a (MTS1) in human thyroid cancer cell lines.

Jones CJ, Shaw JJ, Wyllie FS, Gaillard N, Schlumberger M, Wynford-Thomas D.

Mol Cell Endocrinol. 1996 Jan 15;116(1):115-9.

PMID:
8822272
14.
15.

Homozygous deletions of the p15 (MTS2) and p16 (CDKN2/MTS1) genes in adult T-cell leukemia.

Hatta Y, Hirama T, Miller CW, Yamada Y, Tomonaga M, Koeffler HP.

Blood. 1995 May 15;85(10):2699-704.

16.

Genetic evidence in melanoma and bladder cancers that p16 and p53 function in separate pathways of tumor suppression.

Gruis NA, Weaver-Feldhaus J, Liu Q, Frye C, Eeles R, Orlow I, Lacombe L, Ponce-Castaneda V, Lianes P, Latres E, et al.

Am J Pathol. 1995 May;146(5):1199-206.

17.

Analysis of a family of cyclin-dependent kinase inhibitors: p15/MTS2/INK4B, p16/MTS1/INK4A, and p18 genes in acute lymphoblastic leukemia of childhood.

Takeuchi S, Bartram CR, Seriu T, Miller CW, Tobler A, Janssen JW, Reiter A, Ludwig WD, Zimmermann M, Schwaller J, et al.

Blood. 1995 Jul 15;86(2):755-60.

18.

Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma.

Caldas C, Hahn SA, da Costa LT, Redston MS, Schutte M, Seymour AB, Weinstein CL, Hruban RH, Yeo CJ, Kern SE.

Nat Genet. 1994 Sep;8(1):27-32. Erratum in: Nat Genet 1994 Dec;8(4):410.

PMID:
7726912
19.

Homozygous loss of the cyclin-dependent kinase 4-inhibitor (p16) gene in human leukemias.

Ogawa S, Hirano N, Sato N, Takahashi T, Hangaishi A, Tanaka K, Kurokawa M, Tanaka T, Mitani K, Yazaki Y, et al.

Blood. 1994 Oct 15;84(8):2431-5.

20.

MTS1/CDKN2 gene mutations are rare in primary human astrocytomas with allelic loss of chromosome 9p.

Ueki K, Rubio MP, Ramesh V, Correa KM, Rutter JL, von Deimling A, Buckler AJ, Gusella JF, Louis DN.

Hum Mol Genet. 1994 Oct;3(10):1841-5.

PMID:
7849711
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