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Results: 1 to 20 of 111

Similar articles for PubMed (Select 7997262)

1.

Crystal structure of the tyrosine kinase domain of the human insulin receptor.

Hubbard SR, Wei L, Ellis L, Hendrickson WA.

Nature. 1994 Dec 22-29;372(6508):746-54.

PMID:
7997262
3.

Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism.

Mohammadi M, Schlessinger J, Hubbard SR.

Cell. 1996 Aug 23;86(4):577-87.

4.

Identification of an autoinhibitory domain in the insulin receptor tyrosine kinase.

Filipek A, Soderling TR.

Mol Cell Biochem. 1993 Mar 24;120(2):103-10.

PMID:
8487750
5.

Structural determinants of substrate selection by the human insulin-receptor protein-tyrosine kinase.

Keane NE, Chavanieu A, Quirk PG, Evans JS, Levine BA, Calas B, Wei L, Ellis L.

Eur J Biochem. 1994 Dec 1;226(2):525-36.

6.

Crystallographic and solution studies of an activation loop mutant of the insulin receptor tyrosine kinase: insights into kinase mechanism.

Till JH, Ablooglu AJ, Frankel M, Bishop SM, Kohanski RA, Hubbard SR.

J Biol Chem. 2001 Mar 30;276(13):10049-55. Epub 2000 Dec 21.

7.

Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket.

Villa F, Deak M, Bloomberg GB, Alessi DR, van Aalten DM.

J Biol Chem. 2005 Mar 4;280(9):8180-7. Epub 2004 Dec 20.

8.

Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region.

Wybenga-Groot LE, Baskin B, Ong SH, Tong J, Pawson T, Sicheri F.

Cell. 2001 Sep 21;106(6):745-57.

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12.

Biochemical and structural characterization of a novel class of inhibitors of the type 1 insulin-like growth factor and insulin receptor kinases.

Bell IM, Stirdivant SM, Ahern J, Culberson JC, Darke PL, Dinsmore CJ, Drakas RA, Gallicchio SN, Graham SL, Heimbrook DC, Hall DL, Hua J, Kett NR, Kim AS, Kornienko M, Kuo LC, Munshi SK, Quigley AG, Reid JC, Trotter BW, Waxman LH, Williams TM, Zartman CB.

Biochemistry. 2005 Jul 12;44(27):9430-40.

PMID:
15996097
13.

In vitro phosphorylation of insulin receptor substrate 1 by protein kinase C-zeta: functional analysis and identification of novel phosphorylation sites.

Sommerfeld MR, Metzger S, Stosik M, Tennagels N, Eckel J.

Biochemistry. 2004 May 18;43(19):5888-901.

PMID:
15134463
14.
15.

Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor.

Hu J, Liu J, Ghirlando R, Saltiel AR, Hubbard SR.

Mol Cell. 2003 Dec;12(6):1379-89.

PMID:
14690593
16.

Crystal structure of the kinase domain of human vascular endothelial growth factor receptor 2: a key enzyme in angiogenesis.

McTigue MA, Wickersham JA, Pinko C, Showalter RE, Parast CV, Tempczyk-Russell A, Gehring MR, Mroczkowski B, Kan CC, Villafranca JE, Appelt K.

Structure. 1999 Mar 15;7(3):319-30.

PMID:
10368301
17.

Crystal structure of bisphosphorylated IGF-1 receptor kinase: insight into domain movements upon kinase activation.

Pautsch A, Zoephel A, Ahorn H, Spevak W, Hauptmann R, Nar H.

Structure. 2001 Oct;9(10):955-65.

PMID:
11591350
18.

Identification of major tyrosine phosphorylation sites in the human insulin receptor substrate Gab-1 by insulin receptor kinase in vitro.

Lehr S, Kotzka J, Herkner A, Sikmann A, Meyer HE, Krone W, Müller-Wieland D.

Biochemistry. 2000 Sep 5;39(35):10898-907.

PMID:
10978177
19.

Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2.

Wu J, Tseng YD, Xu CF, Neubert TA, White MF, Hubbard SR.

Nat Struct Mol Biol. 2008 Mar;15(3):251-8. doi: 10.1038/nsmb.1388. Epub 2008 Feb 17.

PMID:
18278056
20.

Structural characterisation of substrate binding to the human insulin receptor tyrosine kinase domain.

Gao Y, Keane N, Levine BA, Alejos R, Ellis L.

Biochem Soc Trans. 1992 Aug;20(3):269S. No abstract available.

PMID:
1330772
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