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Items: 1 to 20 of 136

1.

A role for Rac in Tiam1-induced membrane ruffling and invasion.

Michiels F, Habets GG, Stam JC, van der Kammen RA, Collard JG.

Nature. 1995 May 25;375(6529):338-40.

PMID:
7753201
2.

Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling.

Stam JC, Michiels F, van der Kammen RA, Moolenaar WH, Collard JG.

EMBO J. 1998 Jul 15;17(14):4066-74.

3.

Oncogenic activity of Tiam1 and Rac1 in NIH3T3 cells.

van Leeuwen FN, van der Kammen RA, Habets GG, Collard JG.

Oncogene. 1995 Dec 7;11(11):2215-21.

PMID:
8570171
4.

Lfc and Lsc oncoproteins represent two new guanine nucleotide exchange factors for the Rho GTP-binding protein.

Glaven JA, Whitehead IP, Nomanbhoy T, Kay R, Cerione RA.

J Biol Chem. 1996 Nov 1;271(44):27374-81.

5.

Mechanisms of guanine nucleotide exchange and Rac-mediated signaling revealed by a dominant negative trio mutant.

Debreceni B, Gao Y, Guo F, Zhu K, Jia B, Zheng Y.

J Biol Chem. 2004 Jan 30;279(5):3777-86. Epub 2003 Nov 3.

6.

Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation.

Michiels F, Stam JC, Hordijk PL, van der Kammen RA, Ruuls-Van Stalle L, Feltkamp CA, Collard JG.

J Cell Biol. 1997 Apr 21;137(2):387-98.

7.

Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression.

Engers R, Springer E, Michiels F, Collard JG, Gabbert HE.

J Biol Chem. 2001 Nov 9;276(45):41889-97. Epub 2001 Sep 10.

8.

Rho-like GTPases: their role in cell adhesion and invasion.

Michiels F, Collard JG.

Biochem Soc Symp. 1999;65:125-46. Review.

PMID:
10320937
9.
10.

Direct involvement of the small GTP-binding protein Rho in lbc oncogene function.

Zheng Y, Olson MF, Hall A, Cerione RA, Toksoz D.

J Biol Chem. 1995 Apr 21;270(16):9031-4.

11.

[Role of the multifunctional Trio protein in the control of the Rac1 and RhoA gtpase signaling pathways].

Bellanger JM, Zugasti O, Lazaro JB, Diriong S, Lamb N, Sardet C, Debant A.

C R Seances Soc Biol Fil. 1998;192(2):367-74. French.

PMID:
9759378
12.

Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation.

Qiu RG, Abo A, McCormick F, Symons M.

Mol Cell Biol. 1997 Jun;17(6):3449-58.

13.

The guanine nucleotide exchange factor Tiam1: a Janus-faced molecule in cellular signaling.

Boissier P, Huynh-Do U.

Cell Signal. 2014 Mar;26(3):483-91. doi: 10.1016/j.cellsig.2013.11.034. Epub 2013 Dec 2. Review.

PMID:
24308970
14.

Identification of the stef gene that encodes a novel guanine nucleotide exchange factor specific for Rac1.

Hoshino M, Sone M, Fukata M, Kuroda S, Kaibuchi K, Nabeshima Y, Hama C.

J Biol Chem. 1999 Jun 18;274(25):17837-44.

15.

The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.

Leeuwen FN, Kain HE, Kammen RA, Michiels F, Kranenburg OW, Collard JG.

J Cell Biol. 1997 Nov 3;139(3):797-807.

16.

The nucleotide exchange rates of rho and rac small GTP-binding proteins are enhanced to different extents by their regulatory protein Smg GDS.

Sasaki T, Kato M, Nishiyama T, Takai Y.

Biochem Biophys Res Commun. 1993 Aug 16;194(3):1188-93.

PMID:
8352776
17.

DEF6, a novel PH-DH-like domain protein, is an upstream activator of the Rho GTPases Rac1, Cdc42, and RhoA.

Mavrakis KJ, McKinlay KJ, Jones P, Sablitzky F.

Exp Cell Res. 2004 Apr 1;294(2):335-44.

PMID:
15023524
18.

The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor.

Zheng Y, Fischer DJ, Santos MF, Tigyi G, Pasteris NG, Gorski JL, Xu Y.

J Biol Chem. 1996 Dec 27;271(52):33169-72.

19.

Targeting of Tiam1 to the plasma membrane requires the cooperative function of the N-terminal pleckstrin homology domain and an adjacent protein interaction domain.

Stam JC, Sander EE, Michiels F, van Leeuwen FN, Kain HE, van der Kammen RA, Collard JG.

J Biol Chem. 1997 Nov 7;272(45):28447-54.

20.

Rac-1 dependent stimulation of the JNK/SAPK signaling pathway by Vav.

Crespo P, Bustelo XR, Aaronson DS, Coso OA, Lopez-Barahona M, Barbacid M, Gutkind JS.

Oncogene. 1996 Aug 1;13(3):455-60.

PMID:
8760286
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