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Results: 1 to 20 of 250

1.

Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways.

Lowin B, Hahne M, Mattmann C, Tschopp J.

Nature. 1994 Aug 25;370(6491):650-2.

PMID:
7520535
[PubMed - indexed for MEDLINE]
2.

Concanamycin A, a powerful tool for characterization and estimation of contribution of perforin- and Fas-based lytic pathways in cell-mediated cytotoxicity.

Kataoka T, Shinohara N, Takayama H, Takaku K, Kondo S, Yonehara S, Nagai K.

J Immunol. 1996 May 15;156(10):3678-86.

PMID:
8621902
[PubMed - indexed for MEDLINE]
3.

Tumor-specific CTL kill murine renal cancer cells using both perforin and Fas ligand-mediated lysis in vitro, but cause tumor regression in vivo in the absence of perforin.

Seki N, Brooks AD, Carter CR, Back TC, Parsoneault EM, Smyth MJ, Wiltrout RH, Sayers TJ.

J Immunol. 2002 Apr 1;168(7):3484-92.

PMID:
11907109
[PubMed - indexed for MEDLINE]
Free Article
4.

Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity.

Kägi D, Vignaux F, Ledermann B, Bürki K, Depraetere V, Nagata S, Hengartner H, Golstein P.

Science. 1994 Jul 22;265(5171):528-30.

PMID:
7518614
[PubMed - indexed for MEDLINE]
5.

Comparison of Fas(Apo-1/CD95)- and perforin-mediated cytotoxicity in primary T lymphocytes.

Lowin B, Mattman C, Hahne M, Tschopp J.

Int Immunol. 1996 Jan;8(1):57-63.

PMID:
8671589
[PubMed - indexed for MEDLINE]
Free Article
6.

Bcl-2 protects against Fas-based but not perforin-based T cell-mediated cytolysis.

Lee RK, Spielman J, Podack ER.

Int Immunol. 1996 Jul;8(7):991-1000.

PMID:
8757944
[PubMed - indexed for MEDLINE]
Free Article
7.

MRL/lpr CD4- CD8- and CD8+ T cells, respectively, mediate Fas-dependent and perforin cytotoxic pathways.

Benihoud K, Bonardelle D, Bobé P, Kiger N.

Eur J Immunol. 1997 Feb;27(2):415-20.

PMID:
9045912
[PubMed - indexed for MEDLINE]
8.

Altered peptide ligands trigger perforin- rather than Fas-dependent cell lysis.

Bachmann MF, Ohteki T, Faienza KM, Zakarian A, Kägi D, Speiser DE, Ohashi PS.

J Immunol. 1997 Nov 1;159(9):4165-70.

PMID:
9379009
[PubMed - indexed for MEDLINE]
9.

IL-4 diminishes perforin-mediated and increases Fas ligand-mediated cytotoxicity In vivo.

Aung S, Graham BS.

J Immunol. 2000 Apr 1;164(7):3487-93.

PMID:
10725701
[PubMed - indexed for MEDLINE]
Free Article
10.

Essential roles of perforin in antigen-specific cytotoxicity mediated by human CD4+ T lymphocytes: analysis using the combination of hereditary perforin-deficient effector cells and Fas-deficient target cells.

Yanai F, Ishii E, Kojima K, Hasegawa A, Azuma T, Hirose S, Suga N, Mitsudome A, Zaitsu M, Ishida Y, Shirakata Y, Sayama K, Hashimoto K, Yasukawa M.

J Immunol. 2003 Feb 15;170(4):2205-13.

PMID:
12574394
[PubMed - indexed for MEDLINE]
Free Article
11.

Fas- and perforin-independent mechanism of cytotoxic T lymphocyte.

Kajino K, Kajino Y, Greene MI.

Immunol Res. 1998;17(1-2):89-93. Review.

PMID:
9479571
[PubMed - indexed for MEDLINE]
12.

IL-1 beta convertase (ICE) does not play a requisite role in apoptosis induced in T lymphoblasts by Fas-dependent or Fas-independent CTL effector mechanisms.

Smith DJ, McGuire MJ, Tocci MJ, Thiele DL.

J Immunol. 1997 Jan 1;158(1):163-70.

PMID:
8977187
[PubMed - indexed for MEDLINE]
13.

Comparing the relative role of perforin/granzyme versus Fas/Fas ligand cytotoxic pathways in CD8+ T cell-mediated insulin-dependent diabetes mellitus.

Kreuwel HT, Morgan DJ, Krahl T, Ko A, Sarvetnick N, Sherman LA.

J Immunol. 1999 Oct 15;163(8):4335-41.

PMID:
10510373
[PubMed - indexed for MEDLINE]
Free Article
14.

The CTL's kiss of death.

Berke G.

Cell. 1995 Apr 7;81(1):9-12. Review.

PMID:
7536631
[PubMed - indexed for MEDLINE]
Free Article
15.

Veto activity of activated bone marrow does not require perforin and Fas ligand.

Chrobak P, Gress RE.

Cell Immunol. 2001 Mar 15;208(2):80-7.

PMID:
11333140
[PubMed - indexed for MEDLINE]
16.

Differential contribution of Fas- and perforin-mediated mechanisms to the cell-mediated cytotoxic activity of naive and in vivo-primed intestinal intraepithelial lymphocytes.

Corazza N, Müller S, Brunner T, Kägi D, Mueller C.

J Immunol. 2000 Jan 1;164(1):398-403.

PMID:
10605035
[PubMed - indexed for MEDLINE]
Free Article
17.

Comparison of Fas- versus perforin-mediated pathways of cytotoxicity in TCR- and Thy-1-activated murine T cells.

Kojima H, Toda M, Sitkovsky MV.

Int Immunol. 2000 Mar;12(3):365-74.

PMID:
10700471
[PubMed - indexed for MEDLINE]
Free Article
18.

Regulation of Fas(Apo-1/CD95)- and perforin-mediated lytic pathways of primary cytotoxic T lymphocytes by the protooncogene bcl-2.

Schröter M, Lowin B, Borner C, Tschopp J.

Eur J Immunol. 1995 Dec;25(12):3509-13.

PMID:
8566045
[PubMed - indexed for MEDLINE]
19.

Identification of a population of CD4+ CTL that utilizes a perforin- rather than a Fas ligand-dependent cytotoxic mechanism.

Williams NS, Engelhard VH.

J Immunol. 1996 Jan 1;156(1):153-9.

PMID:
8598456
[PubMed - indexed for MEDLINE]
20.

Virally infected hepatocytes are resistant to perforin-dependent CTL effector mechanisms.

Kafrouni MI, Brown GR, Thiele DL.

J Immunol. 2001 Aug 1;167(3):1566-74.

PMID:
11466378
[PubMed - indexed for MEDLINE]
Free Article
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